>>29440129
The setting is Magic, the Gathering, set on the plane of Mirrodin in the Scars of Mirrodin block.
M:tG's setting revolves around countless different planes that powerful travelling wizards called Planeswalkers travel between.
One of these places is Mirrodin, a world where life has melded with metal and machinery. Copper forests, mercury oceans, that sort of thing. Otherwise everything is mundane.
The latest villain is the rebirth of an ancient faction called Phyrexia, artificial monstrosities dedicated to transforming all of existence into a single, efficient organism, corrupting and assimilating everything in their path.
In its current incarnation, Phyrexia is split up into five factions according to the five types of mana in the setting. Red for industry, fire and freedom, Green for evolution, nature and instinct, Blue for science, water and scheming, Black for corruption, death and ambition and White for order, life and discipline.
The character in the OP image is called Elesh Norn, the Praetor (leader) of the white aspect of Phyrexia, known as the Machine Orthodoxy.
To find out more about her and her faction, read here:
>http://www.wizards.com/magic/magazine/article.aspx?x=mtg/daily/stf/137