/sci/ - Science & Math

op watch this they have a whole section on irreducible complexity

http://www.youtube.com/watch?v=Ohd5uqzlwsU

>implying you will watch any of this

>>3984540
glial cells have typically been thought of as the "support cells" of the brain, only aiding neurons, but they make up 90% of the human brain.

research proposal for my PhD written in the style of an NIH grant


>>3984544
I'm not EK

>>3984529
The US gov't hasn't banned all use of hESC though. Some dickhead researchers who use adult stem cells tried to get an injunction and get it banned but it was overturned/denied. And hESC for now are the gold standard when it comes to this research. We aren't totally sure EXACTLY how identical to hESC cells are to the iPS.

There were 3 papers published last year calling this into question

http://www.nature.com/nature/journal/v471/n7336/full/471046a.html

>>3984514
>>3984514
No I didn't obtain any tissues. We have skin samples from patients and the embryonic stem cells we use are the ones that were isolated by the government a long time ago.

and I'm trying to coax them into glial cells which you could classify as neuronal, but they aren't neurons. That's a bit of a simplification, but I'm doing other stuff also

>>3984492
That is the Yamanaka paper. Reprogramming differentiated cells back to stem like states. Ever heard of iPS cells? That's this paper.

Also I'm using mice and human embryonic stem cells.

>>3984475
that isn't what I do, but
>implying you don't want glowing pets

>>3984474
the title of my project is "Differentiation of Human Pluripotent Cells and Fibroblasts to Region Specified Glial Progenitors"

>>3984452
>implying

do what you love. If the whole world was physicists and mathematicians it would suck.

besides regenerative medicine is much cooler

>>3984445
>implying this isn't the greatest time to be a biologist

finally run Crysis on maxed settings

>>3984410

probably http://www.cell.com/abstract/S0092-8674(06)00976-7

Ask someone who should be writing a proposal but is procrastinating anything.

Maybe it's because foreign films suck ass

I'm in grad school now. No one cares about grades as long as they stay above a B average

>>2979195
Feels good. At least when the Chinese overlords take over there will be a better chance they won't put me in a forced labor camp.

>>2979200
>What's the most interesting piece of information you've learned in your studies?
That some people don't consider embryonic stem cells to actually be stem cells because it is a very transient cell type that doesn't exist in the adult organism or even in the developing organism for very long.

>What is it about genetics that fascinates you?
That every cell in the body has the exact same set of genes, but can form so many different cell types

>What is the average salary of a geneticist (not a professor)?
no idea

>What future studies do you want to collaborate on?
Hopefully some transplantation experiments with stem cells and other regenerative medicine type things

>>2979108
I'm not sure yet, possibly in academia but i wouldn't discount going into industry; and I might want to be a professor but it depends on how the job market is looking whether or not there are still a lot of baby boomers holding tenured positions.

>>2979113
I don't know if it's really wrong or right. I mean obviously they went extinct for a reason, but it might be helpful if we could study the physiology of these past animals to better understand evolution

bump

>>2978952
Most schools I actually interviewed at require grad students to teach or TA at least 1 class and some even make it so you can get a teaching license or teaching degree along side really easily.

>>2978961
I've never had to do what you're talking about. Usually we want to fix the mouse' tissue so we use the heart to pump a fixative through the body.

>>2978971
PhD and it's 5-6 years average with people finishing faster (3years) or slower (10 years). Most schools I interviewed at had similar numbers.

>>2978972
On the surface to do things like make sure the child has no developmental diseases no. But things in like GATTACA where they go to the doctor and he tells them something like for an extra $X amount we can do this for a Y% chance that your child will be a prodigy might be edging unethical. We don't really understand intelligence and things like that enough to mess with the DNA of embryos

>>2978901
Because my school gives everyone a free copy of MS office 2010.
>>2978906
I suppose I don't really have a favorite. I've never played assassin's creed but I dno't think anything like you describe is possible. Although there is a thought, with some evidence, that things that happen to your grandparents can affect your development through epigenetics

>>2978921
Cell culture and mice. I don't know if I'll use either, but memorizing what you're going to say is usually a bad idea because you'll sound over practiced. I usually just put a few talking points and a picture on the slide and then elaborate off of them.

>>2978928
Not a Canadian University.

>>2978871
like this
http://www.youtube.com/watch?v=d8aVlO9MquM
>>2978875
There may be an underlying genetic basis but the concept of race itself is a social construct developed relatively recently. There is most likely an epigenetic component also
>>2978878
I don't pay to go to school. The school pays my tuition and gives me a stipend. So all things considered it feels pretty good.
>>2978885
There is no requirement at my school for me to TA unless my PI would need me to. I get 25K a year before taxes.

>>2978854
Genetics (PhD)
>>2978856
because I didn't want a real job and wanted to learn more science

>>2838810
okay, and what is it that you don't understand?

>>2838774
wait, people still do Northern blots??

>>2838732
I majored in molecular genetics and I forget my GPA exactly. I think it was around a 3.6ish. A more important thing is your test scores and lab experience.

If your interested in genetics but also medicine I would look into an MD/PhD program and then think about possibly specializing in Medical Genetics. Apparently it is a very in demand field and once you get to that level will be in very high demand.

>>2838744
This is a very long and complicated answer I don't really have the room to type out that involves large cell migrations and morphogen gradients.

>>2838438
A field you might really want to look in to is high throughput DNA sequencing specifially RNAseq. My lab is just starting to get into this a lot with 3 different people in my lab doing various projects with it. There are tons of papers being published in nature, cell, and science every month with these kinds of projects. It's kind of the flavor of things right now, it will be for a while and it seems to be very powerful tool so knowing how to work with computers, program, and analyze these data sets would be very attractive to future graduate programs.

Things are only going to get better once we get single cell sequencing which I think will happen withing 5-10 years