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2023-11: Warosu is now out of extended maintenance.

/sci/ - Science & Math


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9862084 No.9862084 [Reply] [Original]

I asked this question on >>>/g/ but realized it was the wrong place to ask. Will people alive today be able to completely change their appearance or race, along with other genetics with Crispr. A lot of people are doubtful but remember the state of computer technology in the 70s.

>> No.9862094

A lot of human gene editing research done nowadays is on fetuses. Changing the DNA in every cell in your body is a monumental undertaking.

>> No.9862105

>>9862094
yeah but computers in the early 70s were nothing compared to those in the late 90s. A lot happened fast.

>> No.9862132

>>9862105
People also thought we would have fusion and bases on Mars by now, in the 1970s.

>> No.9862143

>>9862084
Race is a social construct, so no.

>Irony of ironies; when genetic engineering really makes it possible to turn someone "genetically white", this is what white supremacists will claim.

>> No.9862169

>>9862132

Technology based off of computers have increased quite rapidly and will likely continue to do so. Although genetic engineering isn't around the corner with artificial intelligence and quantum computing, adult genetic modification is a lot closer than a lot of people think

>>9862084

You will be able to change your appearance, if that's what your asking, but racial divisions have a lot to do with culture so don't expect to be accepted by the community

>> No.9862311

>>9862084
You've finished growing. Changing some building plans won't matter if the building is finished. Your bones etc are done, they won't automatically twist and rearrange themselves to different phenotypes

>> No.9862640

>>9862311
>Your bones etc are done, they won't automatically twist and rearrange themselves to different phenotypes
why not though?

>> No.9862651

Can you change a piece of rye bread into a piece of chocolate cake using chemistry? What you want is much harder.

>> No.9863176

>>9862169
Nope, not happening in vivo

>> No.9863181

>>9862640
Cause you're done growing, son.

>> No.9863210

>>9863181
Do you know what CRISPR is?

>> No.9863236

>>9862311
Your skin cells can easily change pigmentation. This happens without genetic modification in some adults anyways as they get older.

>> No.9863285

>>9862084
race is a social construct, so no. However, CRISPR as it is right now is not enough to enable people to change appearances. For purposes of this discussion embryos do not count as people. First off one needs a way of getting CRISPR and other means of manipulating DNA into cells, then we need a way to prevent the immune system from destroying the modified cells. Really we need gene therapy that works. Until we're regularly treating people with gene therapy for medical purposes, we can't even consider using gene therapy for cosmetic purposes. Of course getting gene therapy to work is only part of this. The next is figuring out what genes to insert. For say skin color this might be comparatively simple , but things that involve changes in structure we have no idea how to do. Growing cat ears would be an example of a structural change. As far as I can tell, we are nowhere close to doing this. We cannot get cell cultures to form desired shapes from genes at all. Growing cat ears is similar to regrowing a limb, but with the added difficulty in that we have to make a completely new structure.

We are not sure if it's possible to make adult humans fully regenerate limbs at all. In addition, there is the possibility that making structural changes to the body might A. be unique to the structural transformation being performed and B. be impossible just through changing genes. The one uses to go from no cat ears to cat ears might differ from person to person. Now one of the prerequisites for accomplishing structural change is that you are able to change what cells are doing in different places. For example, how do we get the genes for growing cat ears to only express themselves on the head? How do we get a gene to express itself only in a desired location? Sure we could only modify genes on the head, but this limits the practicality of these procedures.

>> No.9863304

>>9863285
I suppose one could do something like a tattoo gun that injects the gene therapy only in certain places or light modulated virus particles, but this might be less practical than growing say cat ears and grafting them on. It is probably going to be much harder to do genetic engineering to make a person grow rather than a culture of cells in a vat. That being said, the techniques necessary to do structural transformation, would also be useful to grow organs. So this will probably happen after we can do such things.

So to summarize, we can't predict if or when this will occur, but changing appearance via genes will happen after:
we can get cell cultures to form desired 3d shapes just using gene modification
formation of desired 3d shapes in animal models
Gene therapy has been in regular use and has a similar risk to current cosmetic surgeries
Regeneration of limbs is common place
growth of moderately complicated organs in the lab

>> No.9863306

>>9863210
I don't think you understand.

>> No.9863385

>>9862143
Youtube is a social construct. Therefore it does not exist.

>> No.9863471

>>9863385
You don't actually know what social construct means, do you?

>> No.9863476

>>9862311
A building doesn't usually swap out 99% of it's material like a human body does.

>> No.9863494
File: 137 KB, 400x189, 500x1000px-LL-55626d72_melanotan20overdone2.png [View same] [iqdb] [saucenao] [google]
9863494

>>9863476
Analogy doesn't work. Your bones grow for a while then they "seal themselves in". Humans aren't like butterflies that can cocoon and melt down and completely regrow into a different form, we're already finished. Maybe your pigmentation changes but your bones can't regrow themselves into a different shape. You'll be like this kid here at most, negro (or asian or other race) on the surface but your facial proportions and phenotypes and your height and width and other design hallmarks won't change.

Sorry to burst ur bubble kiddo, at least you might get babies that don't even have your original dna tho

>> No.9863499

>>9862311
You couldn't genetically engineer yourself to just make your body start growing again?

>> No.9863500

>>9863499
Man all you people are brainlets

>> No.9863530

>>9863285
>>9862094
>>9863176
>>9863494
>Until we're regularly treating people with gene therapy for medical purposes, we can't even consider using gene therapy for cosmetic purposes.
We're already doing it with grown animals. We've changed the eye color and the number of cones/rods in *adult* chimpanzees. It's called a retrovirus.

You don't have to worry about cell rejection as you aren't changing the factors that cause it. White blood cells do not run around sampling the DNA of every cell in the body, they just react to foreign antigens.

So, to answer OP, yes, you will one day be able to make some genetic cosmetic changes, though it'll take time and repeated doses for those changes to kick in, and of course, you'll lack certain developmental changes, such as bone structure. (And, as others have pointed out, of course, culture.)

You'd probably end up looking more than a tad weird, and would have to resort to plastic surgery to complete the effect, but you can indeed make genetic changes to adult cells en mass, even if you can't reproduce some factors that are result of long term growth cycles.

>> No.9863764

>>9863530
Why not bones through?

>> No.9864673

>>9862132
We are not far from that, honestly. We are sending people there in 2 years, not every prediction is 100% accurate

>> No.9864931

>>9863500
Thanks for the response, it was very informative. Hopefully genetic engineering will advance to the point that I can cure my brainlet status.

>> No.9865270

>>9864931
Only the lettiest of brainlets would think genetic engineering will fix their intelligence

>> No.9865273

>>9862105
computers are basically rocks compared to human biology - expecting an exponential radiative improvement in gene editing because it happened in transistors is stupid

>> No.9865311

>>9862084
With extensive treatment over the course of several years, maybe in theory.

First and foremost you have to remember you're editing many of the genes associated with the physical features of your body. Second you have to remember that you're not only identifying them, but it's also a treatment that would have to last long enough for your cells to redevelop. In essence, the time it takes for your body to regenerate itself in its entirety (roughly 7 years from what I have heard).

So... ignoring the dump trucks of money you'd need to throw at it, you'd be undergoing gene therapy for several years and would probably have it fucked up.

>> No.9866183

>>9862311
after braces and no retainers, my teeth attempt to move back to the way they were

>> No.9866224

>>9866183
Teeth move very easily, hardly an argument for the restucturing of other more permanent features of the body. Your femur won't grow two inches when you're 50. And if you give yourself wolf dna your teeth won't grow and become wolfs teeth. And your cheekbone won't bulge outwards to make you look more black, youll remain mostly as you are.

>> No.9866231

>>9862105
Computers are not human bodies, dumbass

>> No.9866920

>>9862143

um sweetie, society is a racial construct.

>> No.9866928

>>9862084
>>9866231
This, I've seen """""biohackers'""""' inject themselves with some cancer inducing shit to get big muscles stating in his own words in the future he wants to upload genes like they're apps as if that's anywhere near how the human body works. Current transhumanism isn't scienctific it's scientism worship by fucktards who replace divine big Others with technological ones. That being said, I think changing an organism from an embryonic stage is much more plausible and hopefully, sex slave cat girls come out of it by the time on my death bed.

>> No.9866942
File: 434 KB, 1606x1220, Genetic Data #2 - Chiao and Blizinsky 2009.png [View same] [iqdb] [saucenao] [google]
9866942

>>9866920
>>9862143

Although, in all seriousness, this is a very grimy tactic used by the left.

When the average normie hears "race is a social construct", they think "oh, that must mean that races are genetically the same except for the genes that determine skin colour, hair texture, height, etc.", when that is not what that means.

If you're going to say, "race is a social construct", you have an obligation to clarify that this does not mean genetic sameness, otherwise you are equivocating what these terms entail.

>INb4 "the onus is on them to know what 'social construct'" means, you know damn well what you're doing

>> No.9867023

>>9863499
You'd have to change an absolute laundry list of developmental proteins and probably wait about 20 years (my ballpark guess, don't quote) post-therapy for a human body to readjust, but it is probably possible. Lots of osteoclast/blast gene sets remodeled and such. The real question would by WHY you would spend those burning dumptrucks of grant money on a useless project like changing the human body. Evolution did all of the heavy lifting for us. No need to reinvent the wheel.

>> No.9867027
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9867027

>>9864673
>We are sending people there in 2 years

>> No.9867032

>>9862143
Oh hey Tumblr, enjoy that single digit IQ of yours, xir.

>>9862084
Yeah that's not fucking happening

>> No.9867034

>>9866942
Is that image supposed to be compelling evidence of something? I think any neutral interpretation of it is that the gene has no effect

>> No.9867079
File: 188 KB, 1404x662, Genetic Data.png [View same] [iqdb] [saucenao] [google]
9867079

>>9867034
>>9867034

Well, you're wrong. What, do you think a correlation is invalid if r^2 equals anything less than exactly one?

The real world is messy, and most models are multivariate, and cannot be explained by just one variable, but that is not to say that that variable is not important, or the most important of all variables associated.

>> No.9867086

>>9867079

btw, source is Way and Lieberman
http://www.scn.ucla.edu/pdf/Way(2010)SCAN.pdf

>> No.9868351

Wait a second, wouldn't better biotech (which crispr is a part of) allow you to do plastic surgery on steroids? For instance, strong cheekbones looks good. If you wanted weak cheekbones you could probably do bone shaving like the koreans do, but making them bigger is another problem entirely. But if you were able to grow, implant and fuse bone parts easily, then you could actually add instead of subtract onto the skull, which would open up a lot for plastic surgery.