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/sci/ - Science & Math

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6319439 No.6319439 [Reply] [Original]

Why aren't you guys discussing the most significant advancement in the medical field since Penicillin? Scientists have found that it's possible to turn Mouse cells into stem cells by giving them an acid bath, if this also works with human cells we could have much cheaper, completely ethical source of stem cells.

http://www.bbc.co.uk/news/health-25917270

http://www.nytimes.com/2014/01/30/business/study-says-new-method-could-be-a-quicker-source-of-stem-cells.html?_r=0

>> No.6319442

>>6319439
I have a question? Couldn't you also clone people "ethically" now as well if it works?

>> No.6319451

>>6319439
Holy shit

>> No.6319456

>>6319439
Because iPS stem cells have been available for years. The only thing remarkable about this research is the fact that ANYONE is still working on the cloning method of producing stem cells.

>> No.6319463

>>6319456
Yeah but these have all the properties of embryonic stem cells, iirc the others are still limited in their uses

>> No.6320848

lol fuck ethical concerns... like god cares if we can clone or not

>> No.6322310

>>6319456
iPS stem cells use known oncogenes to induce pluripotentcy. Not only do they have to genetically engineer the oncogenes into the cells in the first place, they have to get them out afterwards. The whole process is expensive and yield is horrible. In other words, iPS stem cells can give you cancer.

Being able to produce nearly-totipotent cells by dunking somatic cells into acid bypasses all the hassle with genetic engineering and would bring stem cell treatments into the mainstream decades ahead of schedule.

>> No.6322326

>I work with stem cells
> My lab partly runs a iPS core facility
>I have made ips cells
>>6319463
You didn't read the article I'm guessing.
They specifically state they don't divide/expand like normal ES cells. They didn't show it with adult mouse cells/it didn't work. Didn't show it in humans and it can be more difficult than you think translating these types of things across species.

>>6322310
You can replace the oncogene c-myc with glis1 and make iPS cells.
Additionally you can use mRNA transfected into the cells or proteins and get iPS cells. There are even methods being developed to use antibodies to replace factors for reprogramming.


It is a very interesting paper though

>> No.6322337

>>6320848
God might not, but the people with all the money do

>> No.6322347 [DELETED] 
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6322347

>>6319439
there are like 4 threads about this already

did you even catalog?

>> No.6322368

>>6319439
because there are so many fuckin consenting humans who want to be bathed in acid

holy shit do you even think

>> No.6322378

>>6319439
Any stock market tips? Which companies are going to start selling people body parts made from their own stem cells?

>> No.6322485

>>6322368
pH 5.7 is about as acidic as milk. Did you take high school chemistry?