Emphasis on germ cell and prenatal endocannabinoid system micro-RNA in rise of the modern mind

[Anonymous No.5205736]

Over the course of human phylogenetics, a hierarchy was formed. This hierarchy entailed the successive alterations of the number of sections of DNA within different types of cells, known as copy number variations. Emigrants from the equator to outside of the tropics found new plants and faced less humidity and thus less infections. Some of the strains and species contributed to the composition of germ cell micro-RNA passed on during procreation, altering such things as stress response and reward systems. Eventually, biomarkers now corroborated with prosperity emerged. This was mostly from the pairing of individuals thriving from previous changes, thus starting a ball rolling exponentially anew relative to the equatorial peoples. The human phylogenetic hierarchy was created, resulting in both stark differences in technology, and of social atmospheres toward civilizations with and without technology. Nutritional neuroscience was altered from environmental availabilities. The resulting animal husbandry, including that of the human animal, became suddenly more relevant and important, sparking a debate between the apathy and empathy toward the genetic drifts.

On a related and important note, the silk road opened Europe to Cannabis, and Cannabis has been shown to improve brain power by getting neuronal mitochondria high. Neuronal mitochondria use cannabinoids as units for resting, decreasing their respiration and the release of reactive oxygen species used during human information processing. This enables the neuroprotection to act as an adaptogen for learning. Judging by the innate pharmacology of the phytochemicals in Cannabis, if it reduces brain power, that person was genetically impoverished to begin with or had no access to literature.

Modulation of Excitatory Synaptic Transmission by Δ9-Tetrahydrocannabinol Switches from Agonist to Antagonist Depending on Firing Rate
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684930/

[Anonymous No.5205745]

Have anything interesting on the benzodiazepide receptor that lacks an endogenous compound?

[Anonymous No.5205757]

>>5205736
>Cannabis has been shown to improve brain power by getting neuronal mitochondria high.
[citation needed]

[Anonymous No.5205760]

Do cannabinoids reduce brain power? http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388600/

I tried to include it several times but it was too long.

[Anonymous No.5205773]

Can you objectively attribute a single invention to cannabinoid receptor activation? And don't give me any nomenclature bullshit about endocannabinoids.

[Anonymous No.5205778]

THC suppresses macrophage natural killer cells and T-lymphocytes and reduces resistance to viral and bacterial infections (Zhang et al., 1999). THC augments the immune inhibitory cytokines IL-10 and TGF-beta and down-regulates IFN-gamma (Zhu et al.). This has been the first clear demonstration that THC promotes tumor growth and supports the epidemiological evidence of an increased risk of cancer among marijuana smokers.

Delta-9-tetrahydrocannabinol (THC) has been shown to decrease Th1 responses (cell mediated immunity) while increasing Th2 responses (humoral immunity), both in vitro and in vivo. THC increases the detection of IL-4 and IL-10, cytokines associated with Th2 responses, and decreases IFN-gamma, IL-15 and IL-12, cytokines associated with Th1 responses. THC suppresses IL-12, IL-15 and IL-6 and increases IL-1 alpha, IL-1 beta, and TNF-alpha in stimulated cultures. IL-12 and IL-15 are known to induce IFN-gamma production from T cells and NK cells and to be involved in the induction of a Th1 response, while IL-1 is considered a growth factor for Th2 cells. (Newton C, Klein T, Friedman H., 1998).

[Anonymous No.5205779]

>>5205760
That shows the exact opposite of the claim that they 'improve' brain power, doesn't it?

[Anonymous No.5205781]

Marijuana has undisputed negative effects on cognitive functioning, including memory, learning and motor coordination. These negative effects persist long after the period of acute intoxication, averaging approximately 30 days of residual cognitive impairment (Bolla et al., 2002; NIDA, 2005; Pope et al., 2001). This means that individuals are apt to wrongly believe they are capable of performing critical tasks, such as driving a car, operating heavy machinery, caring for children or solving work-related intellectual problems, when in fact they may be performing in the mildly to moderately impaired range of functioning.

[Anonymous No.5205786]

>>5205779

Apparently cannabinoid receptor activation makes you smarter if you're smart and stupider if you're stupid. :/

[Anonymous No.5205787]

>>5205773
Just as individual genes don't corroborate with macroscopic analyses, single receptors don't either. Perhaps you may be interested that songbirds rely on endocannabinoid receptor activation to generate new songs. I would be inclined to believe the hippie generation was inadvertently harmonizing with the same dynamic.

[Anonymous No.5205795]

>>5205787

Let me rephrase it. Do any inventions or historical achievements corroborate with the ingestion of phytocannabinoids?

[Anonymous No.5205812]

Historians have not historically recorded their standards of living around the time of the advent of their inventions. If the principle of neuroprotection can be attributed to decreased neural tissue damage from information processing, it would only be a logical extrapolation to presume inventors did not have deprived neuronal mitochondria. The French Renaissance was likely from related to the phytochemicals popular at the time. Some individuals clearly didn't require additional neuroprotection to provide their inventions, for example, Da Vinci. But it's quite possible that he was descended from individuals who had previously acquired CNVs related to phytocannabinoid influence over the endocannabinoid system.

[Anonymous No.5205824]

>>5205786
What? How did you arrive at that conclusion?

[Anonymous No.5205855]

Subjective variation of in vivo voltage gated calcium channel voltages, altering CB1 receptor conformational capacity, is predominantly a function of environmental access and/or demand for information processing. High levels of reading of complex literature has a more pronounced reduction of schizophrenic symptoms both in cannabis-naive and cannabis using patients, than low levels of reading of simple literature. Receptor lateralization plays a role in the chances an individual will be able to read well enough to alter their neural firing rates, and therefore VGCCs, and switch the conformational property of THC to antagonist, where it acts as an adaptogen for learning.

Reading Impairments in Schizophrenia Relate to Individual Differences in Phonological Processing and Oculomotor Control: Evidence From a Gaze-Contingent Moving Window Paradigm. http://www.ncbi.nlm.nih.gov/pubmed/22506755

The origin of brain asymmetry and its psychotic reversal. http://www.ncbi.nlm.nih.gov/pubmed/12615502

[Anonymous No.5205870]

>>5205855
Here's a tip. Let's say you want to direct your post to someone, then you click on the number of their post to automatically include a referral number.

[Max Plank !Hwop/gspA. No.5205876]

>>5205773

one time i made a bong out of a pumpkin

[Anonymous No.5205890]

>>ITT somebody has yet to use the word 'corroborate' correctly

I'm sorry, I just can't take you seriously when your method of approach is rhetorics.

[Anonymous No.5206012]

>>5205890
I'm not sure what this is a reply to, but because this is all unrehearsed on short notice, I expect to accidently misuse words. In any case, I'm positive that my postulate will be taken seriously.

[Anonymous No.5206015]

>>5205736
>TL;DR:: Weed activates your dormant midichlorians

[Anonymous No.5206052]

>>5206015
Emission of Mitochondrial Biophotons and their Effect on Electrical Activity of Membrane via Microtubules http://arxiv.org/abs/1012.3371

Light-induced replication of nanobacteria: a preliminary report. http://www.ncbi.nlm.nih.gov/pubmed/12470452

The midichlorian overlords are overpopulating their slaves!

[Anonymous No.5206264]

Comparative histology of pineal calcification. http://www.ncbi.nlm.nih.gov/pubmed/9690142

The rat pineal gland comprises an endocannabinoid system. http://www.ncbi.nlm.nih.gov/pubmed/18554250

Pineal cross-transplantation (old-to-young and vice versa) as evidence for an endogenous "aging clock". http://www.ncbi.nlm.nih.gov/pubmed/8010614

Link between the early calcium deposition in placenta and nanobacterial-like infection. http://www.ncbi.nlm.nih.gov/pubmed/17954977

[Anonymous No.5206270]

Pineal melatonin level disruption in humans due to electromagnetic fields and ICNIRP limits. http://www.ncbi.nlm.nih.gov/pubmed/23051584

[valjean !!4SOyPF0IuOv No.5206285]

All of the papers I've read say that THC doesn't affect intelligence but does affect memory retention and cognition speed. I'll find some sources in a few minutes, so hold your horses before calling [citation needed]

[valjean !!4SOyPF0IuOv No.5206287]

>>5206285
It affects them negatively, I might add.

[Anonymous No.5207463]

>>5206287
reiterating the dogma doesn't discredit the specifics of my postulate.