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/sci/ - Science & Math


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4186428 No.4186428 [Reply] [Original]

Life extension thread

I'll start off by dumping images of the full text of this study (which does not have open access):

Vitamin D and mortality in older men and women
Clinical Endocrinology, Volume 71, Number 5, November 2009 , pp. 666-672(7)

>> No.4186441

>>4186428
This ought to be interesting.

>> No.4186460
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>> No.4186592
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>that feel when you'll have a 120th birthday

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>> No.4186687
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Come on, /sci/. There have got to be some people knowledgeable about this.

>> No.4186748

>>4186687
Not on /sci/.
Here, we mostly have arguments between naive singularity hopefuls and cynical "brain is complicated we'll all die after oil runs out" pessimists.
I'm sure life extension is possible within the laws of physics, but I'm not confident enough to bet on having access to it.
I expect to live to around 80 years old, so I'm going to seek cookies and soapy tit-wanks between now and then.

Enjoy your qualia while it lasts.
http://en.wikipedia.org/wiki/Qualia

>> No.4186769

I know lobsters can potentially live forever through some means. And there lies the total sum of my expertise on the subject.

>> No.4186772

I just went to the doctor and got told I have a vitamin D deficiency. The doctor told me the same thing the last time I did a blood test, 3-4 years ago.
Nice..

>> No.4187390
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4187390

I intend to have body parts replaced with cybernetics when they wear out. We already replace hips, knees, elbows etc with quite crude prosthetics and in 50 years time, when I'll be needing them, I expect them to have advanced to the point where they are superior to organic ones.

The only really irreplaceable thing in the body is the brain. So long as I don't have a degenerative brain disorder later on, it follows that eventually most or all of the organic body will be replaced with artificial parts, simply as a matter of iteration. Blood can be replaced with artificial blood cells that are currently being developed. Realistically I expect artificial blood to be available around 2025. Some say sooner, some later but the 20's promise to be a decade full of advances.

I'm being optimistic but i don't think i'm being unrealistic. Demand will drive innovation and invention. Right now we stand on the cusp of being able to make clinical immorality a genuine prospect, that said I doubt the majority of the world will benefit from such things as they will only be available to well off upper-middle class people.

Some say we will never achieve effective immorality or mind uploading or endless life extension. To them, I would point them in the direction of 'The fable of the Dragon Tyrant' story.

>> No.4187445
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Durk Pearson and Sandy Shaw literally wrote the book on Life Extension (1982) and pioneered a lot of work with peptides for that purpose.

>> No.4187456

>>4187390
The brain naturally degenerates at 60 years on forward. Sorry to burst your bubble.

>> No.4187458
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4187458

The proteins mTOR and sirtuins are being looked at for their properties in life extension. Some compounds such as resveratrol, which is found in red wine and thought to be very beneficial, work at those molecular targets. Caloric restriction also increases life rate, and is thought to be involved in the mTOR pathway.

The concept of Hormesis as a whole is relevant to life extension. Hormesis is a nonlinear toxicological model where low doses of toxins prove to be very beneficial rather than toxic. Factors such as low dose radiation could then be helpful in life extension. Pic related.