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/sci/ - Science & Math


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4014305 No.4014305 [Reply] [Original]

Immortality thread go.

Are you anxious that you may be a member of the last generation without life extension?

>> No.4014311

Enough that I'm working on it. Fuck if I'm going down without trying.

>> No.4014312
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4014312

50% of americans die from cancer or heart disease
still can't cure acne or common cold

>immortality thread
>mfw

>> No.4014315

>>4014305
No. Immortality is not natural, there's a reason nature will want you dead within so many years.

Living forever? How boring. What's there to look forward to, what motivates you to get started on something if you've got infinite time to do it?

To me the ideal of infinite life does not sound that great, and mark my words, were I ever offered it I would refuse it.

>> No.4014317
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4014317

Ageless and no set lifespan are NOT IMMORTALITY

You're still going to die with a hammer to the brain. Or the HDD, in the case of transhumans.

>> No.4014319

>>4014312
>mfw DRACO

eat shit common cold.

>> No.4014322

>>4014312
reggie's boi faic. intredasting

>> No.4014323
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4014323

>>4014317

Immortality means you CANNOT DIE
You are IM-MORTAL

Mortality, the possibility of death, is not a concept in existence for you.

>> No.4014324

>>4014315
I suppose the Black Plague meant that nature wanted humanity wiped out all those years ago to? Fuck you and fuck off, it's "natural" for the human to progress in all ways possible... even if it means reaching some sort of immortality.

>> No.4014329

>>4014315
>>4014317
Luddites gonna ludd.

>> No.4014333

>>4014324
Why yes, population control has been a constant in all of earth's history. The natural way of things is always that if there's too much of one animal there's always something that kills them off eventually; look it up.

It's some kind of universal order of things.

So what the fuck happens when nobody dies and the population keeps growing, how will everyone on earth be fed? There will be some breaking point down the line.

Resources will be needed.

>> No.4014338 [DELETED] 

>>4014333
SPACE, NIGGER. DO YOU SPEAK IT? We are FAR FAR AWAY from being too big for our britches in this place.

>> No.4014340

>>4014338
And do you think that given the way and order of things right now (profit-driven economic models) anyone will ever invest in something like that?

>> No.4014342 [DELETED] 

Niggas doesn't know about quantum immortality

>> No.4014343

You're already immortal as long as you're a good person and you live in the hearts and minds of those who love you.

>> No.4014344

>>4014340
You're right. Fuck it. Pack it up guys, no reason to research this.

>> No.4014347
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4014347

>>4014329

Not a Luddite. Just want mortals to stop confusing agelessness with immortality.

Death waits for everything. The atoms you are made of are not infinite.

>> No.4014350
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4014350

Lets do this, or not die trying.... wait.

>> No.4014353

>>4014323
are you intentionally ignoring the fact that we're using the term immortality to as shorthand for "practically endless life due to improvements in technology but will nonetheless not prevent a bullet from killing you"? because otherwise your post is worthless

>> No.4014357

I don't think there's any real path to immortality anyway.

Motherfucker, if I cut your head off and stick dynamite in the holes and blow you to bits I think I can pretty much guarantee you're not gonna live.

Which begs the question; if you have a clone made of you right now and you die and the clone takes your place would you live on as the clone?

>> No.4014361

>>4014347
>Death waits for everything. The atoms you are made of are not infinite.

Bitches don't know about my nanotech

>> No.4014362

yes. i think about this all the time. it sucks, but it could be worse.

i don't see how anyone can say that longevity is bad. there's so much shit to do, and find out and experience. 100 years isnt enough. i realy wish i could live forever. it takes like 10 years to get good at anything too. imagine if we had 1000 years to work at something. we'd be able to do anything.

>> No.4014365

>>4014362
do you really think you can stay focused on improving something for 1000 years?

>> No.4014366

>>4014361
Pretty sure <span class="math"> you [/spoiler] don't know bout your nanotech with that brilliant statement.

>> No.4014368
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4014368

>>4014361

The atoms your nanobots will be made with are not infinite.

>> No.4014370 [DELETED] 
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4014370

Niggas youre all ignoreing >>4014342
this is true immortality right here

>> No.4014374

>>4014343
This is the only man in this thread who makes sense

>> No.4014378

>>4014368
This thread is about LIFE EXTENSION in case you haven't figured this out you nitpicking faggot.

>> No.4014379

>that feel when "immortality" will only allow ugly rich people to spend more of their lifetime screwing everyone over

>> No.4014382

>>4014315
>what motivates you to get started on something if you've got infinite time to do it?

What motivates you to do something if you'll be dead soon anyways?

>> No.4014383

also this >>4014379

What, do you dumb assholes think they're gonna give it away, whatever it is?
Do you think you'll ever have enough money to get it?

>> No.4014385
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4014385

>>4014378

It's not nitpicking when you're using a word that directly does not apply!

>> No.4014387

>>4014382
exactly.

>What motivates you to do something if you'll be dead soon anyways?

The knowledge that you will make a difference and people will remember you for it after you die.

And that, my friend, is true immortality.

>> No.4014390

>>4014379

>that feel when "literacy" will only allow ugly rich people to spend more of their lifetime reading
>that feel when "plumbing" will only allow ugly rich people to spend more of their lifetime shitting
>that feel when "electricity" will only allow ugly rich people to spend more of their lifetime staying up late
>that feel when "computers" will only allow ugly rich people to spend more of their lifetime looking at porn


hmm.

>> No.4014393

Billionaires are dying right on schedule (largely in their 80s and 90s), surrounded by technical affluence.

Conclusion: Life extension is BUNK. If the billionaires don't bother investing in that, then NOBODY's going to get it.

>> No.4014395

>>4014390
You know all of those things took a long time before they were accessible to us regular folk.

>> No.4014398

>>4014387
probably responding to a troll, but:

>The knowledge that you will make a difference and people will remember you for it
but that also motivates you even if you're immortal

>after you die.
why is this important? I'd prefer to be famous and loved when I'm alive rather than when I'm dead

>> No.4014399

>>4014387
>The knowledge that you will make a difference and people will remember you for it after you die.

Statistically no on both accounts.

Also ignoring that neither of those things improve my quality of life.

>> No.4014400
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4014400

>>4014393
Protip: Billionaires are not always trendsetting scientifically-minded entrepreneurs.

http://www.theage.com.au/technology/sci-tech/drugs-may-let-us-live-to-150-20111016-1lrm5.html

http://www.hplusmagazine.com/articles/forever-young/manhattan-beach-project-end-aging-2029

http://www.ted.com/themes/might_you_live_a_great_deal_longer.html

http://nextbigfuture.com/2011/07/sierra-sciences-working-towards.html

http://www.sens.org/sens-research/research-themes

http://video.google.com/videoplay?docid=-3329065877451441972#

http://www.nature.com/news/2010/101128/full/news.2010.635.html

http://www.guardian.co.uk/science/2010/nov/28/scientists-reverse-ageing-mice-humans

http://www.physorg.com/news/2011-06-biologists-yeast-cells-reverse-aging.html

http://www.physorg.com/news/2011-06-dna-reverse-premature-aging.html

>> No.4014401

I'm 22 now.
Hopefully by 50, my healthplan will allow me to start halting the aging process. Before then, proper upkeep of the body will keep me going strong. If I can keep myself unusually 'young' by the time I'm 80, clone organ and tissue replacement as well as gene therapy could give me another 30 years, long enough to benefit from the next advancement and add a few more years.
I just wanna live long enough to keep going. Who'd wanna stop?

>> No.4014403

I mean, really, folks. What the FUCK makes you retards think that you're gonna have life extension, if the fucking billionaires of your time are dropping dead before their century mark? Are YOU going to have something that billionaires won't have?

/sci/ : Clubhouse for Delusional Miltons

>> No.4014404

>>4014395

Of them, only literacy was actually oppressed, by greedy taxmakers (read: the church).

>> No.4014408

>>4014393
you don't think that maybe some of them are like people on this thread, who think dying at 80 is natural and appropriate? You don't think there's some people like Steve Jobs, who for all his wealth chose homeopathy over conventional cancer treatments?

>> No.4014409

>>4014395
The length of time those things took to reach us has decreased in the order he listed.

Literacy and plumbing have both varied wildly in who has them over the years.

Electricity only took around a hundred years and computers have only taken around 40 years.

>> No.4014412

>>4014404

They may not have been actively kept out of the hands of poorer people, but when the technology was first getting around a vast majority of people couldn't afford any of those things.

Hell my mom lived in a house without toilets when she was a kid, plumbing being a requirement for a home is somewhat recent.

>> No.4014413

>>4014403
Progress and wealth are not accurately connected.

>> No.4014420
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4014420

>>4014305
Anti-ageing technology or not, I'm a blond male. We're perceived as being younger than we really are. At 50, most think we're in our 30's, so long as we aren't balding and are in reasonably good shape.

I'm on my 2nd degree (master's) at 25. I'd like to live a good, long time. However, if it isn't possible, I look forward to a perfectly reasonable 100 years. I also look forward to at least 30 more years of looking good and feeling great.

By the way, anti-senescence technology aside, there are some keys to feeling young:
>Keep an active lifestyle. Dance (a formal dance style like tango, salsa, waltz, swing, etc.) and take liberties with ladies, practice a sport or two (fencing is great for your ass, finswimming is similarly good for your core), keep an exciting hobby (hunting works, so does flying if you have or want a license, and scuba diving is ideal) and travel often.

I know a 74 year old PhD chemical engineer. The guy dates women less than half his age, is still in shockingly good shape, is a tango instructor, takes annual hunting vacations to South Africa and Mozambique, is a licensed private pilot, and is a master diver. No anti-senescence technology for him, but he seems to work well enough without it.

>> No.4014427

>>4014400
> Protip: Billionaires are not always trendsetting scientifically-minded entrepreneurs.

Protip: Billionaires are PEOPLE, and people always have a huge motivation to NOT FUCKING DIE.

And yet they're dying, and right on schedule. So that tells you everything you need to know about "life extension". By the end of this century, you're gonna read about life extension by the light of candles in racy scifi novels (since the fucking oil will be gone, hence most technology).

You /sci/ tards are totally stuck on stupid about futurism, and so much so that you can't even admit what's going on NOW.

>> No.4014428

>>4014412
The point is that the technology is expected to reach a point where it's affordable to everyone - not initially, but over time. The people working those technologies consider it a moral imperative to make it so.

>> No.4014433

>>4014427
Totally agree.

You spent your entire life amassing an amazing fortune but you're not going to take any of it with you when you die.

I assume you would do anything within your power to try to live and enjoy your success as long as possible.

>> No.4014437

>>4014427
>the fucking oil will be gone
Oh it's this west-hating faggot again.

>> No.4014445

>DURR HURR BILLIONARES ARE DYING NOW LOLOL
Yeah. Future life extension. Those guys are 80, we're in our 20's. This isn't a hard concept to grasp.

>> No.4014453
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4014453

>>4014433
This is why I plan to have a pyramid constructed in my honor.

I want my pets to be cared for by my descendants until they die, then they'll be taxidermied and placed in the pyramid. I also want a microbrewery, as per ancient Egyptian tradition. ~90 meters tall with 4 obelisks with hieroglyphics depicting my life's achievements at every point of the pyramid.

>Leave money to an endowment foundation.
>Foundation will host an annual festival in your memory until the money runs out.
>Survivors will speak, recounting your life until there are no more first-hand witnesses. Then, you use historians or personnel designated by the foundation to honor your memory.
>Fuck it, you're dead. Might as well leave behind a legacy that includes one hell of a party.

Also, I'd like to donate a ton of money to my fraternity with the caveat that the nearest 5 chapters must attend my annual memorial celebration.

>> No.4014462

>>4014427
You could make the same argument about, say, cancer 100 years ago.

Also, as mentioned before, see billionaire Steve Jobs opting for homeopathy.

>> No.4014473

>>4014453
>yfw you can do all that even if you're living.

>> No.4014474

>>4014462
> You could make the same argument about, say, cancer 100 years ago.

I didn't realize cancer has been defeated in the West. Link?

I guess all those people that I hear dying from cancer AT ALL FUCKING AGES is just a big joke that's being played on me. All those people are still alive and have only moved away or something!

Here's what happens to we middle class when we get cancer:

1. Half of the time, we die from it. In the first half of the time, it might take a couple of years, but we DO die from it.
2. In the other half of the time, the cancer goes into a light remission. 8-10 years might pass, but largely it comes back and then it pretty much kills us then.

So all that "investment" against cancer didn't seem to do DICK. If you're the middle class, and they diagnose you for cancer, you'd better have your will written up since you're not going to be around for long after that.

So we're back to the REALITY of it all: Life extension is a bunch of snake oil, and it's even worse than that, since you can't even find this particular brand of snake oil for sale on any shelf. Life extension is a non-starter. There are no products or services of "life extension". And the billionaires keep dropping dead, having lived full but totally telomere-dictated lifespans. They live very well, BUT THEY STILL DIE.

>> No.4014482

ITT: Guys jerking it and one guy who forgot about making synthetic oil and refuses to admit the possibility that we might be better at generating electricity in 90 years than we are today.

>> No.4014487

>>4014445
> Yeah. Future life extension. Those guys are 80, we're in our 20's. This isn't a hard concept to grasp.

What's hard for you futurism autists to grasp, is that you ALREADY LIVE IN THE FUCKING FUTURE. And it sucks. It's boring and warlike and economically depressed, and full of time-wasting consumer technology. In short, it's like a William Gibson novel, without any of the interesting parts. Or useful parts.

There's no INCREMENTALISM to life extension. Nobody's getting "lifex" treatments. Why not? BECAUSE IT'S NOT REALLY BEING DEVELOPED, you stupid fucking asshole! And you're not going to spend your own life pursuing that EITHER, since like the rest of your violent-simian brethren, you're only going to be chasing MONEY for the majority of your life, not actual HUMAN ADVANCEMENT.

>> No.4014493

>>4014487
>you ALREADY LIVE IN THE FUCKING FUTURE
I'm convinced you do not know what the word 'future' means.

>> No.4014495

>>4014482
> ITT: Guys jerking it and one guy who forgot about making synthetic oil and refuses to admit the possibility that we might be better at generating electricity in 90 years than we are today.

Synthetic oil isn't economic like natural petroleum. Thanks for revealing clearly that you don't understand economics and as such, are not qualified to speak on the topic of petroleum whatsoever.

>> No.4014504

>There's no INCREMENTALISM to life extension
So what, it'd just all of a sudden happen? Yeah, science does that.
Of course it will be incremental, just as it has been for the past 200 years. An advancement in nanotech here, a new drug to stop telomeres from breaking down without causing cancer there, it will all start adding up...just as current drugs make humans healthier than we were 100 years ago.
>lrn2progress

>> No.4014505

>>4014487
>Violent simian
Still up to your old antics, eh?

>> No.4014506

>>4014493
> I'm convinced you do not know what the word 'future' means.

And it's apparent that you intend to keep dreaming of a future that never arrives. The future has already arrived for things like fusion, which has proven IMPOSSIBLE for Humans to sustain for power production. So we already live in the future, insofar as fusion is concerned. The future already arrived for that.

And the future is already here for life extension, and clearly it's a non-starter, since the people with the MOST resources and BEST motivations for life extension, are doing nothing about it. And yet you retards with your coming lives of economic suffering, are somehow planning on some magic event occurring that gets you the precise thing that should exist today, but DOES NOT.

The Western media fills your heads full of nonsense.

>> No.4014507

>>4014495
>it's expensive to do it today
>therefore, it will always be expensive to do it
That's why we all pay $15,000 on a printer, right?

>> No.4014511

>>4014506
Cite a single source. For any claim.

>> No.4014512

>>4014504
> Of course it will be incremental, just as it has been for the past 200 years.

There is no incrementalism to life extension. PERIOD. What you're poorly referring to is better diet (which isn't life extension) and better routine medical care (which isn't life extension). So you believe you're talking about life extension, but you're not. And it only too 1.5 seconds to figure that out, so you must be one of the best educated morons EVER.

>> No.4014515

>>4014495

Except the economics of the future will be markedly different from that of today. Global population is slowing in increase. We just passed the 7 billionth people mark and for the first time it's projected to take longer to add the next billion than it was the last. Since you're talking about a hypothetical future with really badly picked axioms, I'm as qualified as you are to talk about it.

>> No.4014517

>>4014512
>better diet
>better care
>this extends life
>this is life extension
>holy balls I'm talking to a monkey

>> No.4014518

>>4014474
you are under the illusion that technology goes from being unable to deal with any disease to curing everyone.
I'm claiming that if I had cancer, I'd rather be in 2011 than 1811.

and the billionaires argument has been addressed. they're not going invest in something that is still 40~ years away.

>> No.4014522

>>4014315
>implying anyone wants to live FOREVER

oh shit no. i'd be perfectly content with my own FTL exploration vessel and about a billion year lifespan. that'll give me plenty of time to toodle around, see the sights, live the life, settle down some some crazy sentient alien monstrosity you gain feelings for. ect.

80 or 100 years is way too fucking short, but anything more than a billion years is probably too long

>> No.4014532
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4014532

>violent simian

>> No.4014533

>>4014522
actually this seems like a potential sci fi plot point

has there ever been a work of fiction which deals with a person in this kind of scenario, but becomes an amnesiac for whatever reason and doesn't realize he's essentially an interstellar sandals wearing tourist?

>> No.4014535

>>4014505
oh. is this the guy who's life revolves around peak oil?

>> No.4014536

>>4014515
> Except the economics of the future will be markedly different from that of today.

No, they will be worse, since you 20th-Cen retards were raised on CHEAP OIL. We no longer have that, and nothing replaces it.

Don't even bother responding if you 'think' you can argue around that.

>>4014517
> >this is life extension

No, life extension is the means of countering the natural aging process, like cellular degradation and senescence. Any fool can life a better lifestyle and attain his ideal maximum age. THE KEY IS THAT MAXIMUM AGE. Life extension is what's supposed to address that.

And, that monkey you're thinking about? IT'S YOURSELF.

>> No.4014538

>>4014518
> you are under the illusion that technology goes from being unable to deal with any disease to curing everyone.

You retards talk about life extension as if it could actually extend life past the natural limit. That's where you fail. Eating right and exercising and seeking early medical care are what's fulfilling the natural limit. But you TALK like you're going to break that limit. You are doing nothing of the sort. And the efforts so far are doing nothing of the sort either.

Go in for your telomere-correction treatments and come out to tell me that I'm full of shit. Oh wait, nobody's doing that, so your ability tell tell me that I'm full of shit is JUST ABOUT ZERO.

>> No.4014539
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4014539

>>4014536

>> No.4014542

>>4014538
>it is impossible because i say it is
i mean, it's probably not going to drop next tuesday, but eventually life extension techniques will make it into the private sector

>> No.4014543

>>4014535
If it walks like a fish, talks like a fish, and speaks in CAPITAL LETTERS and Proper Nouns, it's probably him.

>> No.4014544

>>4014533
Wowbagger, the Infinitely Prolonged, but that's not quite the same.

>> No.4014546

>>4014536
>people start living to 70
>"70 is the natural limit!"
>people start living to 80
>"80 is the natural limit!"
>people now comfortably living to 90's
>"that's the natural limit!"
Life is being extended. Has been for a few decades. New tech will increase the rate. Oil is meaningless, a transitional sludge we'll have forgotten about in a century or two. Violent Simian, you have some serious projection issues you should work out, not to mention extreme pessimism. You should take some xannax to level yourself out. Chill and watch some TED talks from people much smarter than either of us on why the next 50 years will be fun to live through.

>> No.4014552

>>4014538
>Go in for your telomere-correction treatments and come out to tell me that I'm full of shit

We're back to that whole "you don't understand the word 'future' " thing again? It's not ready today. The work is being done so it will be ready in the future, which may I remind you, is the word for time that hasn't come yet.
Some assbag like you probably talked about how all of Europe would collapse without whale oil in the 1700's.

>> No.4014572

>>4014552
> The work is being done so it will be ready in the future, which may I remind you, is the word for time that hasn't come yet.

That's vaporware. I've heard you futurists out for decades, and you've got no ammo, but you sure like to wave your guns around a lot as if that makes up the difference.

The 20th-Cen made the most delusional people to have ever existed. There's no excuse for people like y'all to be so delusional while being do highly educated. 95% of you don't even know about the Great Depression that the West is in right now. 90% of Liberals actually believe (as they sit a home unemployed) that Obama "avoided a depression".

In other words, if you people were just stupid, we could chalk that up as such, and move on, simply moving you retards aside. But you KNOW you're wrong, and yet you continue to DEFEND being that wrong. As if defending being wrong makes it somehow RIGHT.

Looking at the sorry state of physics today, where the math fucks have won and lots and lots of physicists believe in stuff merely because their academic superiors demand that they do, it's easy to see why you fuckers believe that "majority rules" with physical facts.

>> No.4014578

>>4014572
a decent bit of futurists were correct, if you did some poking around

the really "popular" ones were like flying cars and such, because they weren't really based on any current science at the time and looked good at disney expos. and oddly enough, if you think about it, a good deal of the predictions in those videos are pretty much possible right now.

>> No.4014580

How to live longer NOW:

Diet: keto / paleo

Physical: low impact cardio daily

Mental: video games, logic puzzles

Social: surround yourself with people who genuinely care about you

THAT'S ALL FOLKS

>> No.4014582

>>4014572

I can tell you're a moron because you used 'Liberal' as an insult. In my experience, anyone who uses 'liberal' or 'conservative' as an insult is a moron, there are no exceptions.

>> No.4014583

>>4014580
indeed, this'll easily put you into your 90s barring any cancer or heart troubles (unlikely with the right diet and low stress and lots of exercise)

>> No.4014585

>>4014546

>I've heard you futurists out for decades, and you've got no ammo
>futurists say in the 70s that the silicon chip may one day affect our daily lives, that fax machines will be household appliances and that robots will do factory work

Futurists rarely get everything right, but I don't think a popular group of predictions for the future have ever been universally wrong, either.

>> No.4014586

The first person to live to the age of 150 has already been born. Also I'm going to make as much money as possible so when the technological singulatiry occurs in 2045 I'll be able to buy any life extending treatment and then immortality when it's available.

>> No.4014589

>>4014586
that's what i'm doing, i have my "extender fund", which diverts some percentage of my paycheck into a bank account that cannot be accessed until, say, 2030.

i calculate that if my income is consistent until that point, i'll have a good 750,000 to spend

>> No.4014593
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4014593

>>4014572
You are all kinds of crazy I don't even know where to begin. I mean, nobody can be this wrong about everything without really trying hard at it. Let me sum it up like this:

Over a dozen links to technology demonstrations and talks of current work being done have been posted in support of the idea that progress will continue.

You have cited nothing.

We'll wait.

>> No.4014595
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4014595

>>4014589
I have an 'extender fund', too. But mine is just for a specific part of my body, if you catch my drift.

>> No.4014597
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4014597

Everyone please remember that captain Violent Simian does not listen to you.

>> No.4014613
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4014613

>>4014597
just like everyone else

>> No.4014617

>>4014586
>money
>post-singularity

>>4014589
I hope you're signed up to some kind of cryonics program too.

>> No.4014626

>>4014617
>cryonics
hell no, it's a waste of money at this point mostly because those companies will probably fold soon enough, and they need to keep their occupants frozen long enough for, like, individual cellular surgery technology to become available. no sir.

i'm waiting until they fully flesh out that technique of using supercooled glucose, which puts the body into deep freeze but keeps all cell walls intact. the canadian wood frog does this to freeze in the winter then thaw in the spring

>> No.4014627

>>4014333
>IF NOBODY DIED THEN EVERYONE WOULD DIE!

>> No.4014631

>>4014580
CALORIC RESTRICTION!
How to live longer and feel like shit doing it.

>> No.4014633

this thread in this vid:
http://www.youtube.com/watch?v=sO7HWoE79Pk

>> No.4014655
File: 81 KB, 360x328, just_saiyan_RE_The_Off_topic_topic_post_2_Return_of_Confusion-s360x328-164470.jpg [View same] [iqdb] [saucenao] [google]
4014655

I dunno if we'll have the technology to extend our lives indefinitely, but I think technological 'immortality' is the most elegant solution to interstellar travel. A twenty year voyage to a nearby star wouldn't seem so bad to someone who has been alive for over a thousand years.

>> No.4014700

>>4014655
no one is seriously saying that we're going to make some sort of immortality pill. the idea is, is that human life expectancy is beginning to increase by more than a year every year. Which means that by the time you're so old you risk dieing of X, X has a cure.
A great recent example is organ failure. You can make brand new organs by seeding cellular "scaffolding" with your stem cells that has been derived from a healthy organ (doesn't even have to be human) or even printed out. Heart starts to go out on you? get a brand new one. it'll be 70 years before it gives out again. With that out of the way it's up to the other myriad age related diseases to kill you.

>> No.4014702

>>4014700
organ printing isn't really up to snuff yet. we're sitll a decade away from printing a full heart

>> No.4014708

>>4014702
Only a decade away for that kind of stuff still makes me moist.

>> No.4014711

>>4014572

That's because Obama did end a recession (or at least his Presidency correlated with an end in negative GDP growth). There is no real way of classifying a depression, but a recession is considered to be two consecutive quarters of negative GDP growth, and US GDP growth is positive at the moment. Sure, unemployment is high (although it has been decreasing lately), and the real rate of inflation reported is dubious due to changes in the way CPI is measured - but the USA is DEFINITELY NOT in a recession or a depression - you'd have to be a fucking idiot to think that it is.

>> No.4014712

>>4014708
well, a decade if we don't hit any snags and the only real obstacle is developing better and more reliable techniques to print the tissues correctly.

if the problem can be reduced to the point that it's just a parallel to developing better processors as opposed to, say, getting fusion working, a decade will be about right

>> No.4014715
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4014715

>>4014712
>SCIENCE PREVAILS

>> No.4014875

Why do these threads always deteriorate into off-topic shitposting? Is it completely impossible to discuss, say, which mechanism is most likely responsible for mitochondrial dysfunction?

>> No.4014976

>>4014875

Hi. I actually keep in touch with Aubrey de Grey and Ray Kurzweil (If you e-mail them with coherent questions and stuff, they'll get back to you. Also, I work as an undergrad in a lab that works on aging, so that helps too).

Mitochondrial disfunction is a result of damage to mtDNA which encodes 13 mitochondrial proteins. Evolution has taken care of part of the problem of mtDNA damage by transferring most of the genes which encode mitochondrial proteins back to the nucleus, which is protected from reactive oxygen species which damage the DNA. Those proteins encoded in the nucleus travel through the TIM/TOM complex of the mitochondria, and become part of the oxidative phosphorylation cascade (And other parts).

mitoSENS calls for moving those last 13 proteins in the mitochondria back to the nucleus by using gene therapy. However, those last 13 proteins are very hydrophobic and would be difficult to transport from the cytoplasm and through to the TIM/TOM complex. Therefore, it would be best to modify the 13 proteins in such a way that would allow them to be encoded by the nDNA and then transported to the mitochondria, which would involve making them less hydrophobic or somehow changing their structure.

>> No.4015003

>>It's not natural
Good point. Do you have anywhere to go with it? Nature does not want us to live longer than a century. It tries to kill us off. Who cares about what someone that wants us to die. If nature says we should be living in the trees running from lions, we defy nature. if it has decided we are temporary, defy nature.

>life will get boring forever
This argument could be used for any age. 100 years can be boring if you are that type of person. Some people get bored at 20. Do you want to die today? Will you tomorrow? Why limit yourself from deciding tomarrow, or the next day. Life is a series of days, ask a child if 70 years is a long time, then ask a 70 year old. Most elderly that want death do so because of health and limits.

Consider the following: if the average person lives to 70, and the first two decades or so are school, people must be careful how they spend their time. Want to get two doctorates? have fun wasting nearly two decades of the five you have left.
Live 200 years, and 1/10 of your life seems less drastic than 1/3.5.

>> No.4015008

>>4014976
I'm actually pretty familiar with the literature in this field - Survival of the Slowest is a relatively controversial mechanism due to the fact that mitochondria engage in periodic fusion and fission, sharing their contents and attempting to nullify the detrimental effects of accumulated oxidative damage.

SoS states that certain types of mutations - those that tend to fully knock out oxphos - propagate throughout the cell due to what basically amounts to survival of the fittest. Mitochondrial fusion would allow for the continuation of oxphos, however, even if that particular mitochondrion's DNA is in shambles. That would SEEM like a decisive point against the SoS hypothesis, but the literature also indicates that mitochondria with a low membrane potential ('slow' mitochondria would have a low membrane potential due to the lack of a proton gradient) do not engage in fusion very effectively or often.

Do you have any thoughts on this issue? I realize that allotopic expression would probably be a solution regardless of the specific mechanism, but it's still important to consider.

I'm also curious about what de Grey would say about POLG mutations, given that he indicates that the only pertinent nDNA mutations are those that cause cancer. Incompetent mtDNA replication due to defective polymerase gamma wouldn't necessarily matter too much if the proteins are being imported, but could lead to malformed proteins being constructed simultaneously (in the mitochondria) and erroneously incorporated into complexes I and IV.

>> No.4015010

>>4015008
(Not following anything.)
This thread is the best thread on /sci/ right now.

>> No.4015032

>>4015008

Hi, thanks for the response. First of all, I'd say that the mechanism is somewhat irrelevant given the fact that mitochondrial takeover has been confirmed in low concentrations in the tissues of the elderly. However, if you'd like a mechanism, this is what Aubrey has to say:
Here's what Aubrey has to say about that.

"Right. A lot of people make this mistake. There are quite a few issues that relate to exactly WHY clonal expansion happens in spite of the points you make. One big one is that fusion may well be a lot less frequent in vivo than in the cell culture model systems that have been studied, because it may be promoted by oxidative stress. Another is that fusion uses the proton gradient: thus, if, just by luck, a single mitochondrion happens to avoid fusion for a short while, it and its descendents may then avoid fusion forever. But as Michael notes, really this is all secondary, because the fact of clonal expansion of mutant mtDNA is very easy to confirm using laser microdissection and such like, and has been well established since years before I came along. All I provided was a proposed mechanism."

>> No.4015038

>>4015032
Thanks. I've read Ending Aging but didn't see that particular topic addressed in there. It seemed as though the lack of a proton gradient would indeed interfere with fusion but I hadn't seen the question addressed directly with regards to clonal expansion. The more you know!

>> No.4015253

Dzugan is a company that does life-extension stuff.

You go in and get a lot of blood drawn, and they compare what you have with the norm for 20 year old people. Then they give you supplements to make up the difference, and check your blood levels every so often.

My parents do it, and they've been more active and happy ever since.

>> No.4015423

>>4015253
> My parents do it, and they've been more active and happy ever since.

That just means they are indulging in taking better care of themselves. They are STILL FUCKING AGING. And their bodies are set at limit for aging.

In now way, shape or form have you established ANTI-AGING. You must either STOP the aging process with anti-aging, or UNDO the aging process with anti-aging.

None of you fuckers posting today will live beyond a total of 100 years. Life extension is not being seriously worked on, PERIOD. Nobody dares to perform Human experiments that allow our cellular death mechanisms to be stopped or reversed. And if anyone was daring to do it, they have NO FUCKING RESULTS for us, since the billionaires are still dying right on schedule.

>> No.4015488

>>4015423

Hahaha, you sound just like one of the genome project naysayers. You'll be eating your words relatively soon.

While you're busy being completely convinced of what the future will hold, I'll be busy creating it. Cya motherfucker :)

>> No.4015499
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4015499

>ITT: People thinking 'immortality' refers to actual immortality.

Yes of course you can die of a hammer to the HDD you inane fucks.

>> No.4015512

>>4015499

Or to the brain if you're still a flesher.

>> No.4015514

>>4015499
Agelessness? Agelessness.

>> No.4015520
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4015520

>>4015512

>2011
>Still using a brain to implement your neural state vector

>> No.4015524

>>4015514

Negligible Senescence or Arbitrary Lifespan.

Or Agelessness.

>> No.4015531

>>4014533

Was working on it, then I realised I have A.D.D and got distracted by something else.

>> No.4015532

Yes except the true immortals will be wearing exoskeltal systems made of carbon fiber hammers will do barely anything.

>> No.4015539

>>4015499
>the only furry image i can get a boner for.jpg
i have no idea what it is
but that image is hot as fuck

>> No.4015543
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4015543

>>4015539

She's a clouded leopard bartender.

I've adapted her to be a character in my WIP about transhumanism.

>> No.4015550

Immortality would suck balls big time. There's only so much life a person can take. Unless some fundamental change to our basic psychology occurs.

>> No.4015563
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4015563

>>4015550

>Unless some fundamental change to our basic psychology occurs.

>implying it won't

Unless, you don't want to or something.

>> No.4015564

>>4015550
immortality becomes much less boring when you're given an FLT vessel and a ticket to ride anywhere in the universe

bonus points if you wear a cheap Hawaiian shirt and sandals with socks everywhere, so you can TRULY represent human culture abroad

>> No.4015569

How is death by bullet/hammer different from death by cancer or death by flu?

It looks like "immortality" as we have defined it would consist of improving medicine to the point where disease is not a problem. But then again, wouldn't a bullet wound just consist of some pierced organs, broken bones, and severed blood vessels, all of which medicine of the future could deal with? And by then, we will have little doctor nanobots in our blood vessels working 24/7 to keep our bodies in check, so the only way to kill somebody would be to completely vaporize them.

Where is the line being drawn? When does the influence of medicine stop in our definition of immortality?

>> No.4015598

to everyone stating that extended life means that you would never be productive, i have a question:

are you saying that the whole basis of your productive life is BECAUSE you're going to die? because that it an absolutely ridiculous form of motivation; in fact, i think you should top yourselves right now. And for those that are agruing against the principle of extended life, please consider the following:

- if (insert your favoured reputable scientist) had lived, how much further do you think we would have advanced with that persons drive and intellect?
- there is a physical restriction on how much knowledge we can impart on ourselves prior to death, and when we do die, that knowledge is lost unless documented. And if documented, that knowledge an inefficient and potentially labourous process of having learn and fully understand something new.

And finally, on to the over-population propositions. This is very valid point but our populous growth is staggering anyways, and would need to be maintained as it is.Therefore, this shouldnt be the decisive factor contributing to your views on biological immortality.

>> No.4015615

I'm just going to be that guy that actually responds to the OP.

Yes I am afraid of death and actually get kind of pissed off when I think of how shitty my life is going to look for future generations.

>worked himself to death in 40 hour working week
>couldn't afford to travel the world
>laughingwhores.jpg

>> No.4015655

If we cared to, we could easily make huge improvements to our life-spans within 50 years. And this would likely lead to ever more development that could make us, effectively, immortal. This generation could be ageless, to use a more appropriate term. But we won't, because nobody wants to fund anti-aging research, and the fucktarded religious douchebags want us all to die so we can go meet their imaginary gods.

Fuck that shit, I'm gonna do my best to advance relevant fields of research to reach agelessness. There's too much to do for me to die so soon.

>> No.4016826

>>4015423
>And if anyone was daring to do it, they have NO FUCKING RESULTS for us, since the billionaires are still dying right on schedule.

That's not how aging works. There isn't one single type of dysfunction that causes the body to fall apart...it's a cluster of problems that all occur at roughly the same time. Until we've fixed them all, we won't be able to observe a significant increase in life expectancy.

Significant progress is being made in at least one such area. A new (passive) vaccine has already demonstrated tremendous promise in remedying the problems associated with Alzheimer's disease without the detrimental side effects of the first (active) vaccine. Ending Alzheimer's will be the death knell of amyloidosis in general given the similarity among the mechanisms.

>> No.4016842

I don't plan on dying.

>> No.4016851

>>4015655
> If we cared to, we could easily make huge improvements to our life-spans within 50 years
"IF"

If the billionaires don't give a fuck about tackling anti-aging, then what fucking chance do YOU have?

>> No.4016860

>>4016851
http://en.wikipedia.org/wiki/Peter_Thiel

>> No.4017158

>>4016826
> Until we've fixed them all, we won't be able to observe a significant increase in life expectancy.

Oh, whatever. Pull the other leg. Stop pretending that it can't be addressed. There's no such thing as "too hard" with BIOLOGY.

We're just CHOOSING to not create real anti-aging.

>> No.4017256

Bump

>> No.4017326

>Are you anxious that you may be a member of the last generation without life extension?

That generation dies out at least three thousand years ago, right before alchemists did what you think hasn't been done yet,

>> No.4018117

analingus

>> No.4018127

>>4017158
If we did anything harder, it would be a hard science, and we all know that's not true.

>> No.4018265

>>4018127

It really makes me wonder sometimes that we want to AVOID changing the Human condition at our biological level. We talk a mean game about it all, but nobody really steps up and makes it happen.

And then there are all those laws against Human experimentation.

>> No.4018451

>>4018265
The main problem is that the FDA jams up anybody who wants to work on therapies designed specifically to extend life, and treatments that aren't approved by the FDA cannot be implemented clinically.

As a result, facilities like the Apollo Bramwell Hospital are springing up in foreign countries to get around the draconian restrictions that have been imposed upon cutting-edge care in this country.

>> No.4018457

>>4018265
Working on that PhD now, fgt. Not my problem if you aren't walking up to the plate.

>> No.4018467

>can't cure acne
>expecting biological immortality soon

Nope.jpg

Better start dealing with your mortality

>> No.4018479

>>4018467
What's the matter punk, Accutane too good for you?

>> No.4018483

>>4018467
Bigger fish to fry, my good man.