/sci/ - Science & Math

[Anonymous No.3222201]

What's your favourite Protein?

Haemoglobin for me.
Just look at that sexy fellow.

[Anonymous No.3222209]

why can't we take pictures of proteins but we can of atoms

[Anonymous No.3222215]

>>3222209
that was taken with Atomic Force Microscopy. google it... i'm pretty sure that whatever you are measuring with AFM needs to be flat. proteins != flat

[Anonymous No.3222217]

>>3222209

[Anonymous No.3222222]

>>3222215
atoms aren't flat, and objectsat that level(protein size) look more like surfaces which are locally flat.

[Anonymous No.3222226]

>>3222209
Easy, that's because.... errr....

Well fuck me.

[Anonymous No.3222237]

Was tempted to go for foxp3, BCR or ABL. Any kinase kinase kinase is always good too. But it's going to have to be ubiquitin.

[Anonymous No.3222239]

>>3222209
1) too soft, the point will squish the shape into oblivion
2) cant be electrically charged.

[Anonymous No.3222240]

>>3222209
They're a bit more complex, and therefore I would think they are a bit harder to make out aswell.

[Anonymous No.3222253]

I always wondered if our knowledge in chemistry is far enough to not sometimes produce any unsuspected reactions.

I mean, we can't really observe the exact molecule interactions in a micro scale. I mean, are the calculations exact or just approximates?

[Anonymous No.3222254]

it'll probably look something like this , a complicated but locally flat surface

[Anonymous No.3222264]

>>3222254
I wonder if there is somebody here that'd call that picture arousing.

[Anonymous No.3222277]

>>3222264
checking in

[Anonymous No.3222283]

>>3222264
any mathematician would get a boner from looking at it

[Anonymous No.3222290]

pick one

[Anonymous No.3222304]

>>3222290
I always hated Ras and Raf. Maybe I'm autistic.

[Samefag !SHjzCSZsqE No.3222324]

>>3222290
>Study biology
>Learn about Ras and its mutated derivatives H-Ras, N-Ras, K-Ras and others
>mfw there are still biologists who believe in intelligent design

Studying biology does not remove the possibility of a designer. It does, however, remove the possibility of an intelligent one.

[Anonymous No.3222341]

>>3222324
An intelligent one who is deliberately not making perfect organisms.

This is the argument of the only creationist biologist I have ever seen: God is doing a deliberately bad job because he loves us.

[Anonymous No.3222347]

>>3222304
It's rather me being autistic for liking it
It's sadistical but oh-so-statisfying

[Anonymous No.3222359]

obviously god uses a recursive random greedy divide-and-conquer algorithm

[Anonymous No.3222358]

>>3222324
what's up with them... i'm interested

[Anonymous No.3222361]

ATP synthase up in this bitch.

[Anonymous No.3222417]

>>3222361
You got my mechanical engineering in my protein!
And my protein in your mechanical engineering!

[Anonymous No.3222448]

Don't mind me, just being the most phallic protein ever

I even look like a country or a Starship

[Anonymous No.3222497]

Phosphofructokinase is kind of naughty.

[Samefag !SHjzCSZsqE No.3222535]

>>3222358
Ras is a protein involved in cell cycle control. Look at the image...a very large number of arrows (pathways) point to that protein. It's highly important for cell cycle cessation, cell-cell contact, growth signalling, etc.

A single point mutation in Ras - which amino acid is what differentiates H-Ras, K-Ras, etc - is often sufficient to throw the whole cell out of balance and lead to cancer.

This is the case in very few other pathways. Redundancies and checks and balances are commonplace. To see such a weak link in such a critical intersection between pathways is, in my eyes, either evidence of no designer or an incompetent one.

[Anonymous No.3222600]

>>3222535
I don't know much about Biochemistry, but I didn't know we had such important proteins without any double-checks

Can we say how often cancer cells are created by a Ras-mutation? In the sense of'X % of all cases

[Anonymous No.3222618]

>>3222347
...naaah. I don't dislike it for what it does - I was the guy whose shortlist included BCR and ABL. I love death by constitutively active RTK-mediated immortality as much as the next guy, just something about Ras pissed me off.

My favourite protein is ubiquitin, one of the girls from my lectures drew a huge card with a picture of ubiquitin on it for my 21st birthday, and a load of lecture friends signed it. I love macabre proteins.

I just hate Ras and Raf.

[Anonymous No.3222657]

>>3222600
There are a number of dominant oncogenes, and also a bunch of recessive tumour suppressors. It'd be hard to give numbers on how important the MAPK pathway is in terms of all cancers, but it certainly kills a lot of people.

(not the previous ras guy, i'm the guy who hates ras&raf - fuck them)

[Samefag !SHjzCSZsqE No.3222756]

>>3222600
Depends on the type of cancer, but in many types the occurrence of some kind of Ras mutation is between 33-45%.

[Anonymous No.3222837]

>>3222756
>>3222657

Thanks!

[Anonymous No.3222893]

>>3222535
H-ras crystallographer here. Please don't tell me you think that the Ras isoforms are defined by what point mutations lead to a constitutively active protein.
Q61 and G12 say sup.

[Anonymous No.3223427]

Pics of DNA Polymerase beta that I took with Insight II a while back.

[Anonymous No.3223434]

>>3223427

electrostatic potential contours of DNA pol B.

[Anonymous No.3223440]

>>3223427
>>3223434

...and more electrostatic potentials in CHARM and UHBD

[Anonymous No.3223453]

The glucose galactose binding protein,
because I am obliged to care about it for 40 hours a week until august.

Also on the off chance,
GULOSE IS A BITCH ASS SUGAR.
You know who you are.