/sci/ - Science & Math

[Anonymous No.16238138]

Is there anything close to NZT-48 from limitless?

[Anonymous No.16238146]

Dextroamphetamine perfectly replicates the hypermotivation and efficiency (only when you first start using) it doesn't make you a super genius able to learn anything and predict car crashes is the problem, you are still dumb as shit and also it makes you a shell of a human being like in the movie, but regardless if you take it or not

[Anonymous No.16238166]

>>>/lit/23494519

[Anonymous No.16238168]

>>16238166
How is this /lit/ related?

[Anonymous No.16238182]

>>16238138
Armodafinil

[Anonymous No.16238192]

>>16238138
Not really. The closest might be oxiracetam and some phenylpiracetam derivatives.

>>16238146
>>16238182
are sorta right too.

[Anonymous No.16238200]

>>16238182
different from modafinil?

[Anonymous No.16238205]

>>16238200
same chemical. but only one isomer of it

[Anonymous No.16238294]

I kid you not, today I was doing dishes and somehow I remembered this movie. Damn

[Anonymous No.16238308]

>>16238294
Synchronicity

[Anonymous No.16238385]

>>16238308
Spooky

[Anonymous No.16238403]

cocaine is one hell of a drug

[Anonymous No.16238427]

>>16238385
>>16238294
>>16238308
>>>/x/

[Anonymous No.16238547]

>>16238182
>>16238200
I thought these were just supposed to keep you awake for longer, not enhance your cognitive ability

[Anonymous No.16238560]

A Drug That Could Give You Perfect Visual Memory By Annalee Newitz
Published July 2, 2009
https://gizmodo.com/a-drug-that-could-give-you-perfect-visual-memory-30975567

They found that if they boosted production of a protein called RGS-14 (pictured) in that area of the visual cortex in mice, it dramatically affected the animals' ability to remember objects they had seen.

Mice with the RGS-14 boost could remember objects they had seen for up to two months. Ordinarily the same mice would only be able to remember these objects for about an hour.

====

LIMK1 Protein
Researchers at the Catholic University in Rome and the Fondazione Policlinico Universitario Agostino Gemelli IRCCS have genetically modified the LIMK1 protein, which is crucial for memory. They added a "molecular switch" activated by the drug rapamycin. This modification enhances synaptic plasticity, which is essential for memory formation and cognitive function. The study suggests that controlling LIMK1 activity can promote memory improvement, especially in age-related cognitive decline.

RPT6 Protein
Virginia Tech researchers discovered a new role for the RPT6 protein, which is part of the proteasome complex. RPT6 can bind to DNA and regulate gene expression during memory formation. This dual functionality of RPT6 opens new avenues for understanding and potentially manipulating memory processes. The research indicates that RPT6 could be targeted for therapeutic interventions to enhance memory or alleviate memory disorders such as PTSD and Alzheimer's disease.

====

CREB Molecule:
A 2015 study identified over 750 genes that can influence long-term memory. These genes activate a molecule known as CREB (cAMP-response element-binding protein), which is required for long-term memory in many organisms. There is a direct relationship between CREB and long-term memory, and many organisms lose CREB as they age

[Anonymous No.16238568]

Asking PERPLEXITY AI.

Are CREB molecules, CREB (cAMP-response element-binding protein), available for purchase?
(COPY-PASTE ABOVE QUESTION INTO PERPLEXITY to get weblinks as 4CHAN will probably block them as "Spam").

Yes, the search results clearly indicate that CREB (cAMP-response element-binding protein) molecules and related products are commercially available for purchase from various biotechnology companies.

The key evidence from the search results is:
GeneCopoeia offers a "GLuc-ON™ CREB transcriptional response element (TRE) clone" containing tandem repeats of the cAMP response element (CRE) upstream of a luciferase reporter gene, allowing analysis of the cAMP and PKA signaling pathways involving CREB.

BPS Bioscience provides a "CRE/CREB Transient Pack" which includes a CREB luciferase reporter vector with multimerized CRE elements to monitor CREB activity and the cAMP/PKA pathway in cultured cells.

Several companies like MyBioSource and Biomatik offer ELISA (Enzyme-Linked Immunosorbent Assay) kits specifically designed to detect and quantify CREB protein levels in biological samples from mice and humans.

RayBiotech sells recombinant human CREB-1 protein transfected into HEK293 cell lysates, providing a source of the CREB protein itself.

OmniMabs offers a CREB ELISA kit for detecting CREB levels in sheep samples.

Cayman Chemical provides the recombinant human CREB-binding protein bromodomain, which is a domain involved in CREB-mediated transcriptional regulation.

These search results collectively demonstrate that various forms of CREB molecules, including DNA constructs, recombinant proteins, cell lysates, and detection kits, are commercially available from multiple biotechnology vendors for research and experimental purposes

[Cult of Passion No.16238666]

>>16238138
Ascension.

Expecting a pill is asking for a hangover. Youre looking up from the middle but not considering the down, faceplant.

[Cult of Passion No.16238672]

>>16238666
>666
CORRECT.

DO WHAT THOU WILT.

[Cult of Passion No.16238695]

>>16238560
Transhumanism.

I activated my genes by life experience. If youre not a Geneticist or MD your opinion here is worthless, as the technical break in cycle of organic activation is clear to me.

BioPhysicist means my signal tells Molecular Biologists what they get to work with, the next station down the line...

Im tracking the Organic Signal...and any break or defects entering the system.

[Anonymous No.16238741]

>>16238138
>Is there anything close to NZT-48 from limitless?
No, shitskin.
There is no magic pill that will make you East Asian, White, Jewish or Iranian etc.

[Anonymous No.16238755]

>>16238666
Not entirely. There are a number of nootropic compounds out there, albeit less effective than "NZT", which happen to be antioxidant chemicals that are very healthy for you. Selective MAO-B inhibitors, for example, probably prevent Parkison's disease to some degree.

[Anonymous No.16238757]

>>16238695
how much do they pay you

[Cult of Passion No.16238763]

>>16238755
>Not entirely.
Where did you do your thesis?

[Cult of Passion No.16238767]

>>16238763
Ha...who am I kidding, if you posted one I would pop a boner to rape you.

Im an Evolutionary Biologists...we tell Medical Doctors what "The Science™" is now.

[Cult of Passion No.16238773]

>Im into Pharmacology.
Sit down, "Experiementalist Chaos Adept".

>Im ascending.
Purchasing products. Not Science.

[Anonymous No.16238776]

>>16238192
Be careful with that stuff though there's a rare side effect of necrotic rashes

[Anonymous No.16238838]

>>16238695
Shut the fuck up and eat another tab. You need ego death or actual death.

[Anonymous No.16239115]

>>16238138
I was obsessed with this as a child

[Anonymous No.16239198]

Selegiline. Sam Bankman-Fraud was on it. It's a Parkinson's drug, selective irreversible MAO-B inhibitor. That doesn't mean lifetime irreversible, but for about 2 weeks post dose your MAO-B enzymes will be inhibited. This leads to an accumulation of dopamine. Higher doses can inhibit MAO-A also and provide an antidepressant effect by additionally raising serotonin and norepinephrine. Just taking even 2.5mg a few times a week should be sufficient. You could develop reckless or compulsive behaviour with excessive inhibition.

[Cult of Passion No.16239204]

>>16238838
YOU ARE NOT A MEDICAL DOCTOR.

>>16238755
>Not entirely.
THIS DEGENERATE JACK ASS IS WHY YOURE A FUCKING MORON


EATING DRUGS AND YOU CONFUSED THE JUNKIE WITH THE DOCTOR.

WHOLY SHIT.....YOU ARE FUCKING STUPID.

STOP POSTING

START LURKING

THIS IS *SCIENCE AND MATHEMATICS*.

GET A PHD OR SHUT YOUR FUCKING COCK-HOLE.

[Anonymous No.16239290]

>>16239198
I always wondered what turned him psycho. It's disinhibition, btw.

[Anonymous No.16239320]

>>16239204
>>16239198
>>16238763
selegiline slowing the progression of parkinson's is not novel science, this shit was known 20 years ago: https://www.neurology.org/doi/abs/10.1212/01.wnl.0000204007.46190.54

>Verification not required.

[Cult of Passion No.16239342]

>>16239320
>https://www.neurology.org/doi/abs/10.1212/01.wnl.0000204007.46190.54
I DONT FUCKING CARE.

IM A DOCTOR TOO AND LECTURE THE BEST IN MULTIPLE FIELDS.

LIKE MICHEAL LEVIN AND JORDAN PETERSON AND BRET WEINSTEIN.

NORMAN WILDBERGER, HIS NUMBER THEORY KING.

>Post Psychiatric garbage from a consumerist industry with corruption and fraud at every level, i cluding legislative...making it systemic.

>>16239320
>selegiline slowing the progression of parkinson's is not novel science
MOLECULE ADDITION TO THE SYSTEM TO ALTER THE BODY.
>>16238755
>Not entirely.
SHUR YOUR FUCKING MOUTH, RETARD.

I DONT CARE WHAT COCKTAIL YOUR DUNCES MAKE.

YOU MADE DR.FAUCI.

STOP CLAPPING YOU FUCKING MONKEY.

[Cult of Passion No.16239346]

>by we ate our own shit and it made us ascended
I DONT FUCKING CARE.

I would LITERALLY fast until death.

100% and fucking proved it.

WALK THE WALK.

STOP THE TALK.

Clap back.
>Clap back.

Lisa needs braces.
>Dental plan.

[New Barkon No.16239463]

>>16239290
You having a moan? You're a bad criminal

[Anonymous No.16239722]

>>16239346

You are unremarkable. You are exactly like all malfunctioning schizos, because your brain is broken in the exact same way.

You are now having this meltdown because you likely deliberately went off your meds.


There is no escape. You are already circling the drain. After you are forcibly deported you will be court ordered to go back on your meds, or report to a facility.


You will go back on your meds and shut the fuck up for approximately 1 more year, until this happens again and we see you in another thread.


This is what you do. This is what your type of schizo does.

You are boring. You are solved. You are a solved problem.

[Anonymous No.16239868]

>>16238138
The part where she finally takes the drug, and has the genius idea to run across the ice and chuck a fucking kid at the bad guy completely and utterly killed this movie for me.

[Cult of Passion No.16239873]

>>16239722
>You
>You
>You
>You

But he doesnt know me...

...theyre all a reflection of him.

>Me
EGO
>Self
PROFIT
>Me
EGO
>Self
Lisa needed braces........................

[Anonymous No.16239877]

>>16238138
Unfortunately, no.

[Anonymous No.16240445]

>>16239290
I meant with excessive inhibition [of MAO-B] at the end. But I understand how it reads wrong

[Anonymous No.16240519]

>>16240445
or to put it another way, monoamine oxidase B is an enzyme of behavioral inhibition because it chemically degrades dopamine, such that inhibiting said enzyme can disinhibit behavior by increasing synaptic dopamine content.

>common side effect of most anti-parkinson's medication

[Anonymous No.16240832]

>>16240519
I'm currently using moclobemide for depression and it has worked like a miracle for me. Only thing is when I increased the dose to 600mg my energy and motivation dropped, despite social skills increasing. So I'm debating adding 1.25-2.5mg selegeline thrice weekly to combat that without needing to lower the moclobemide dose. Kinda concerned about turning into a psycho though. From my understanding such a low dose orally should be mild.

[Anonymous No.16240841]

>>16238138
No.
Nootropics is being held back from actual useful shit by the large number of drooling mouth-breathers who "can't stay awake," "can't focus," "can't concentrate," etc. The offerings are mostly all crude upper shit without anything in the way of amazing memory retrieval and whatnot.