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/sci/ - Science & Math


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15448888 No.15448888 [Reply] [Original]

so why haven't we beat cancer yet

>> No.15448894

>>15448888
Nice get,

Cancer means its working ( the vax)

>> No.15448895

>>15448888
Qrd on this eceleb on whom there are 2 threads on the first page

>> No.15448901 [DELETED] 

>>15448895
absolute redditard.
had a twin brother who died a few years back /lit/ hates him

>> No.15448906 [DELETED] 

>>15448888
I'll bump for interest at the latest, but the last excuse I heard is that there's a lot of different kinds of cancer, and each needs a separate solution. Apparently we have kinda cured a few kinds of cancer, though you gotta catch em before they metastasize.

I do know we spend on cancer research several times over what we spend on the space program, in this country, and a few times over that world wide. We've been doing that since the 70's and yet we seem to have barely scratched the surface after generations. Thus I suspect there's a lot of grift going on, but maybe someone around here is in the field and can provide more detail as to what the latest problems and developments are, anecdotally, at least.

Father died of six different kinds of cancer at once a few years back, with no apparent radiation exposure. They made him a case study because of it.

>> No.15448916

>>15448895
he hosts the crash course youtube series which is a series of education videos that helps students to cram. his brother John Green is a YA author and initially more famous than him but now Hank is more well known

>> No.15448973

>>15448888
It's called water fasting for 28 days straight and the jws don't want you to know this

>> No.15448997

>>15448888
https://www.youtube.com/watch?v=x6a4hMyiwBo

>> No.15449005

>>15448888
>its real
wonderful get and glad we havent cured cancer yet
fuck this FAGGOT

>> No.15449018

>>15448888
desu dont get why people hate on him lol hes pretty cool person

also rip

>> No.15449020 [DELETED] 

>>15449005
>>15449018
>>15448895
>>15448901
Seems we're promoting this guy's social media platform, rather than talking about cancer research, go fig.

>> No.15449021

>>15448888
cancer is subjective, you can beat it for billions of years until last scientist dies

>> No.15449038

>>15448901
holy crud the other one died already? Lmao. I remember hating them both from day one.

>> No.15449059

>>15449021
I've read on /x/ that our thoughts create reality. Sadhguru says everything is karma / your doing. Kastrup, Spira and Tolle say consciousness is fundamental. McGilchrist argues that our left hemisphere has become too dominant in perceiving the world. Leo Gura shares the absolute truth that we are God of our sollipsistic creation. How can we use this knowledge to cure cancer since materialism is clearly lacking understanding of what reality is?

>> No.15449060 [DELETED] 

>>15448973
should you build up to it with a 4 day or go in straight?

>> No.15449082

>>15449020
Instead of more research on chemotherapy, more funding should go to either activating p52 only in cancer cells or gene correction. Neither of which are going to happen because its not profitable lt, so our conversation is pointless.

>> No.15449090

I think the term "cancer" is actually pretty bad nomeclature. Cancer isn't a disease, it's a massive class of diseases. Curing cancer isn't possible, you may be able to cure A cancer

>> No.15449093

>>15449059
cancer is label. rename it and it's defeated!

>> No.15449098

>>15449082
>p52
*p53

>> No.15449100
File: 848 KB, 1387x2048, the fountain.jpg [View same] [iqdb] [saucenao] [google]
15449100

Watching The Fountain is probably a bad idea. Maybe his brother John can watch it.

https://youtu.be/GXkc4RzcBbQ

>> No.15449126 [DELETED] 

>>15449082
They tried something along those lines on my father. It was over $3000 per cc. So it's very profitable, as I'm fairly certain there's no element nor compound on the planet worth that much.

I don't know that there is much in the way of research still being done on chemotherapy, as while it can be improved slightly, particularly in the area of reducing side effects, it's kind of a done science, with limited reliability that isn't likely to be increased much with different drug cocktails.

Immuno-response therapy seems to be the big thing now.

>> No.15449141
File: 551 KB, 1348x1690, Potential_risk_of_cationic_lipid_in_the_Pfizer-BioNTech_vaccine.pdf.png [View same] [iqdb] [saucenao] [google]
15449141

>>15448888
wow, who could have predicted it. Oh yeah, lots of people did, including this guy
https://www.bitchute.com/video/Sn3waTaNsZ7p/
here is this very cancer kek shilling for the vax
https://www.youtube.com/watch?v=IxCHv7T_mao

>> No.15449142

>>15449126
>Immuno-response therapy seems to be the big thing now
If that's true then Thymosin alpha 1 would be selling like Nikes, yet only a niche group of people are ever prescript the compound.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747025/#sec-21title

>> No.15449156 [DELETED] 

>>15449141
We have enough threads shilling this guy's Youtube channel, and I'm sorry, people under 40 die of cancer all the fucking time. It can't be the vax, every time, especially given that the population is up to 90% vaxxed up in a lot of places.

>>15449142
I don't see any information there suggesting it isn't, though it only seems to have 9% efficacy against certain types of cancers. Of those cancers we have cured, the treatments are almost all immuno-therapy based, though often still not covered by insurance.

>> No.15449243

>>15449141
Its depressing how few vaxx posts there are in his comments. Hopefully /pol/ piles in there and writes some comedy gold. I mean, antivaxxers are tards but its funny when they harass people.

>> No.15449289 [DELETED] 

>>15449243
So this is all part of a cancel culture campaign? I see. How cancerous, unironically.

NPA.

>> No.15449374

>>15448888
Because the funding that could go to cancer research is going to Shaniqua's children/AIDS research/public schools for their drag queen story hour programs

>> No.15449385

>>15449374
Its the same optimistic retardation. Trying to defeat cancer is the same as funding liberal money sinks. We can chip away at the human condition here and there, but the ultimate problem is with the game itself, and there will never be a breakthrough to solve that.

>> No.15449476

>>15448906
I’d be happy to answer some questions. I am running an early cancer drug discovery lab at a large pharma company.

To get the discussion started: We have made great progress in some cancers, essentially making them a curable disease, but that depends heavily on detecting them relatively early. So cancer diagnostics and affordable health care are crucial.

Many cancers are still hard to treat, because (1) it is not easy to reliably target only the cancer cells and not the healthy rest of the patient and (2) each patient produces billions of new cancer cells a day, each of which can mutate to evade your therapy. Ultimately there are infinite sub-types of cancers and each cancer in each patient is dynamically responding to the treatment.

Since it is impossible to develop truly personalized cancer therapy with current technologies, we are left with developing the best possible therapies that help the largest possible pool of patients with the best possible efficacy while still making a profitable product. Within these constraints some cancers are within reach, while others are too hard.

For example, certain cancers are too rare to even find a proper population to study the safety of a specific drug in it. So these patient get the next best thing that works in a related cancer with a learger patient population, but that of course leads to less reliable outcomes.

>> No.15449534

>>15449476
no you don't. body degrading from malnutrition, poisoning and inactive life will rot and die, no matter what you faggots do.

>> No.15449560

>>15449385
>the ultimate problem is with the game itself
Wrong. Thousands of years of conditioning has led to the mistaken belief that what we observe today is human nature.

>> No.15449580

>>15449476
>with current technologies
is this a situation where AI can actually help drug discovery and potential outcomes? i'm guessing the bottleneck is adapting treatment to mutations in cell types

>> No.15449639

>>15449580
AI and ML already have great impact in our daily work to predict protein folding, drug binding, or create virtual compounds and virtual drug screens.

It is reasonably easy to foresee a future where the technology exists to diagnose cancerous cells very early and prevent the disease from forming altogether or to prime the immune system to more aggressively attack the cancer cells.

To truly “cure all cancer” a lot of different breakthroughs will have to come together though, only some of which are in the realm of pharmacology:
(1) the ability to test people easily and reliably to detect pre-symptomatic cancer in billions of people many times over their lives;
(2) the data analytics to predict the risk and proper treatment with near certainty, as you don’t want to treat millions of false positives;
(3) a highly modular set of treatment options combining immunology, biologicals and traditional small molecule therapeutics to tailor (near) personal treatment regimes;
(4) advances in public health science and epidemiology to revamp how safety studies, clinical trials and approvals would be done, if every treatment is a one-off special mix;
(5) a willingness of the people to engage in receiving treatment for a disease they have no symptoms from yet;
(6) a socio-economic system that can both, afford the medical treatment and has solid plans on how to productively use the increased population lifespan.

>> No.15449692

The biggest issue is, that it is extremely difficult to recapitulate the complex tumor micro environment and tumor heterogeneity found in each of the patients in any laboratory setting. By using immortalized cell lines, complex 3D cell culture models, tissue sections, and more and more elaborate animal models, we try to get as close as possible to the real thing, but as clinical trial failure rates show, we are only right in very few cases of all attempts. If AI can one day help us bridge the in vitro to in vivo to in the clinic knowledge gaps, that would be a huge success and a massive step forward.

>> No.15449743

>>15449126
The cost billed by the medical system to the patient is hard to translate into the money the Pharma company invested into a mL of compound that has a limited target patient population and strong competition.

Of course, the raw materials in that treatment do not constitute the $3000. That price is determined by factors such as the cost of development, the complexity and length of the clinical approval process, the cost of production, the cost of shipping and logistics, the total patient population available for the length of patent protection, the cost of advertising, the reimbursement laws, the competitive landscape etc etc.

So let’s say as Pharma company spent $1B on developing a new drug and bring it to the market. Let’s say by then there are 7 more years on the patent. But competition may come with a new, better drug in 5 years. Let’s simply say it can treat 100.000 patients per year, that is 500-700.000 sales. So it would have to make $1500-2000 per dose just to break even on the R&D cost. Now it also has to make the drug, distribute it, deal with regulators, do marketing and - after all - make a profit.

You can see how doses can run in thousands and sometimes tens or hundreds of thousands of dollars per dose. Especially for rarer cancers or complex formulations.

>> No.15449763
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15449763

>>15448888
>Cancer cells eat mainly glucose and glutamine
Just stop eating bro, it will cuck the cancer enough for your body to fight it

>> No.15449768 [DELETED] 

>>15448901
>had a twin brother who died a few years back
I might have confused this part with some other youtuber

>> No.15449775

>>15449082
Much, much research and R&D money has been spent on p53 and KRAS as cancer therapy targets, but only recently the first breakthrough therapies have become available. Look here for a good overview.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852246/

Gene editing is still in its infancy and a hallmark of many cancer cells is hyper-mutability. So any editing is likely going to be “unedited” quickly by the cancer if done alone, so a difficult strategy.

>> No.15449783

>>15449775
>Gene editing
Is cancer even genetic? It's probably more enveriomental than genetic considering it keeps going up with time

>> No.15449795

>>15449783
it's both but some cancers have more genetic components than others

>> No.15449801

>>15448906
Many groundbreaking therapies against cancer have been developed in the past decades. Considering the 100s of millions of lives saved, the cost compared to the space program seems small and is probably in range of the saved productivity and taxes these survivors provided. See for example https://amp.cnn.com/cnn/2023/01/12/health/us-cancer-deaths-decline-wellness/index.html
Of course, not all gains are drug discoveries, but the lifestyle changes or HPV vaccines go back to funded cancer research.

>> No.15449831

>>15449783
Ultimately, every cancer cell harbors one or -often- many mutations that together enable it to multiply uncontrollably. That is the hallmark of cancer. Thus cancer always has a “genetic” cause that in theory could be treated by editing the mutations back into the unmutated state. But as i said, that is unlikely to work.

In addition, also what the other poster said, there are genetic predispositions to developing cancer that may run in a family. For example, let’s assume a certain mutation in proteins that normally ensure high fidelity in copying DNA can lead to sloppy copying. That in itself may not a problem, but would make it much more likely to get cancer later.

Truly environmental factors also exist, like smoking, asbestos, radiation …

>> No.15450165

>>15448888
>why haven't we beat cancer yet
Wrong model. It's a body reaction to poison. Prove is easy, all scientists show it are ignored, but can't refuted

The pharma shills over here trick you in theire muuh dna voodoo to hide that. Sure nothing is 100% in med but this is an main thing.

>> No.15450187

>>15448901
I know he hates my chud guts but I wish him well and a return to health so he can continue making breathless basedence videos.

>> No.15450190

We have an erroneous view of the body and the cell. We look at it mechanistically, and perhaps this is why our treatments don’t work; we are not machines, and there are so many variables that come into play that a molecular approach to sickness won’t work.

>> No.15450520

>>15450190
>molecular approach
>doesn't work
so... you got an alternative or are you not going to elaborate

>> No.15450567

get the fucking vaccine chud youre killing grandma

>> No.15450574
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15450574

>>15449059
>we are God of our sollipsistic creation
Jesus is God.

>> No.15450575

>>15448906
Do you have any ideas or theories about why your father might have been afflicted by so many cancers at once?

>> No.15450584

>>15450575
He liked taking dicks up his ass and deepthroating them. Most of the cancers were in his ass and throat. The last one was in his stomach which was probably from swallowing too much semen.

>> No.15450600

cancer is a symtomp of aging
better question is why haven't we beat aging yet?
all the biofaggotry shills that cost tens of billions of dollar didnt' do nuffin to stop aging.

>> No.15450604

>>15450600
Sometimes it take a few billion to realize something is impossible. ex: fusion, and we still haven't realized it yet.

>> No.15450809

>>15450520
Yeah, how about we check on people’s lifestyles and try to see if there’s something there instead of just treating them like cars that need an oil change. If we have been at it for so long and we understand that most diseases are multi factorial, and most diseases cannot be reduced to a nucleotide substitution, we would should maybe take a human (not lab rat) approach to health and consider that disease is part of life, and that things don’t necessarily need to be dealt with immediately, or with extreme methods. The fact that no fucking doctor asks you what the fuck your life looks like when you get a chronic illness is telling that their whole mindset on disease, or people for that matter, is clearly lacking in understanding.

To think clearly about it, we had fucking mice commit cannibalism in a cage for time to time, we interbreed mice (between brothers/sisters), and before doing so the brothers would tear each other apart for a few weeks — then we go ahead and assess immunological function after getting their spleens and smushing them in a plastic tube and assume our findings are relevant because we got a small p value. It is truly a reflection of how out of touch we are.

>> No.15450838

>>15448888
Why did this guy also pop up in my YouTube recommendations? Never watched a single one of his videos, and have never heard of his name before. I don't know what he does, but I don't think he has anything to do with Japanese video games or Japanese music, so not sure why he's being recommended to me.

>> No.15450866

>>15449018
due to piss poor moderation this board has become an anti science schizo board and these are the types of people to wish cancer on others for disagreeing with them.
also it's lymphoma which is one of the most treatable cancers so hopefully he can through it.

>> No.15450900

>>15448997
>>15448888
it feels like all youtubers are getting cancer. or maybe that's just my recommended.

>> No.15450905

gerson therapy, people. gerson therapy. https://youtu.be/s7nQ2fOm7IM

>> No.15450940

>>15448888
Jews don't want "we" to beat it.

Geerd Hamer discovered the cause decades and yet "we" are still as blind regarding the cause of cancer as "we" were decades ago.

>> No.15451041 [DELETED] 

>>15450575
No idea really. We joked about him having pissed off Putin having secretly been a spy and gotten a polonium dose or something, but again, no evidence of radiation. He was living on a thin diet of mostly granola bars, which couldn't have been healthy, but I doubt it'd make you break into multiple cancers.

>> No.15451047 [DELETED] 

>>15450838
The cancel culture campaign is probably wide spread enough to affect the algorithm. I mean, if it made it /sci/ of all places, it's gotta be everywhere.

>> No.15451102

>>15450940
da joooooooooos!

>> No.15451130

I'm paranoid about this shit, bros. Quit smoking years ago and haven't consumed any sugar or artificial food for almost the same amount of time. I have to quit drinking as well, that s a lot harder.

>> No.15451659

>>15448888
How many jabs did science boy take?

>> No.15451703

>>15450600
Not really. More the other way around. Aging is a necessary mechanism to prevent cancer. By making all but selected few tissues with limited lifespan ensures that we are not developing into a cancerous blob by age 5. And after our reproductive age, nature doesn’t care much anymore how “well” you do.

>> No.15451730

>>15450809
I would recommend you look for a more compassionate primary care doctor. And please talk you the animal welfare committee at your animal testing site, as these are reportable protocol violations. Otherwise inbreeding in mice is quite common even in the wild.

See “Population structure and inbreeding in wild house mice (Mus musculus) at different geographic scales”

>> No.15451879

his rape persona finally manifested.

>> No.15451900

>>15449476
what kind of information and techniques would you need in order to make personalized cancer therapy?

>> No.15451937

>>15448888
What the fuck for real what the fuck he's a dad and bas a wife and family oh fuck no..... This is like seeing a friend go wtf

>> No.15451941

>>15448916
How TF is hank more well known now I've been out of the loop

>> No.15451947

>>15451941
hank hosts an education series with hundreds of videos in it that is popular with school kids. he got funding from the dept of education so he can produce a lot of videos
https://youtube.com/@crashcourse

>> No.15451949

>>15451947
John did an equal amount of videos there iirc bro

>> No.15452062

>>15448888
Pisses me off that I didn't get the vaxx and I still got cancer. Same type as this onions male too

>> No.15452134

>>15450940
>Geerd Hamer
Take a look at lothar hinreise.

>> No.15452139

Safe and effectiv-HAHAAHAHAHAHAHAHA NO REFUNDS HAHAHAHAHAAHAHAHAHHHAHAAAAHAHAAAAHAAAAAAAAHHAHAHAHA

>> No.15452148
File: 2.49 MB, 1280x720, 1684597855788210.webm [View same] [iqdb] [saucenao] [google]
15452148

>>15448895
He has 10 YouTube channels and him and his twin brother have been making videos forever

>> No.15452157

>>15448888
Sometimes cancer tests show up positive when there is no cancer. The scientific consensus is that cancer has no basis in biology, and is a social construct. You must be trying to justify hatred and oppression for those with cancer by focusing on what makes us different. This is morally reprehensible.

>> No.15452177
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15452177

>> No.15452204

>>15452148
this guy looks like a two feet tall johnny sins

>> No.15452375

>>15452062
Good luck anon. Ganbare.

>> No.15452385

>>15449476
>while still making a profitable product
Fucking cockroaches

>> No.15452391

>>15451041
>He was living on a thin diet of mostly granola bars
Sweeteners?

>> No.15452395

>>15448973
Which increases autophagy, which some cancers use to spread.

>> No.15452397 [DELETED] 

>>15452391
Coulda been, I suppose, but he never became diabetic, and had been fit and thin his whole life.

>> No.15452400

>>15449141
The vaccine sucks, but cancer existed before the vaccine.

>> No.15452402

>>15449763
>Just stop eating bro, it will cuck the cancer enough for your body to fight it
Cancer releases cortisol to break down muscle, and then it feeds on the glutamine that is released. It can also take in exogenous fatty acids. It also takes in glucose (which is always available) to create its own fatty acids. There's a reason cancer is a pain in the ass, because it can find sources of nutrition no matter what you do.

>> No.15452426
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15452426

>>15448888
>so why haven't we beat cancer yet
More money in TREATING diseases than curing them.

>> No.15452440

>>15448888
>John Green
That guy is a faggot. He deserves to get cancer.

>> No.15452447

>>15449018
He is a neckbeard faggot.

>> No.15452475

>>15452440
this unironically

>> No.15452690

>>15451900
The ability to reliably and non-invasively sample the cancerous tissue. Liquid biopsies are developing but are not available for all cancer and tumor types yet due to different rates in cell and dna shedding.

The ability to perform whole genome single cell sequencing cheaply to define the Mutationen landscape of the patient and to follow the tumors response to treatment.

The bioinformatics and systems biology pipelines to integrate the mutational burden into a deregulated pathway picture.

The therapeutic modalities to effectively attack the cancers weaknesses individually or in combination over multiple rounds of counter-evolution.

Alternatively, the ability to perform virtual screenings for highly efficacious drugs based on the specific patient needs and to very cost effectively synthesize those in small, high quality batches.

>> No.15452790

I thought shit like heat shock therapy was getting popular. It's not a perfect treatment but the whole combination treatment method shows promise

>> No.15452954

>>15452177
lmfao, vaxxies get what they fucking deserve.

>> No.15453060

>>15450838
> but I don't think he has anything to do with Japanese video games or Japanese music
cancer anon, it's in the title

>> No.15453085

>>15452157
> Greek physicians Hippocrates and Galen, among others, noted similarity of crabs to some tumors with swollen veins.

it's just tumors, swelling. hippofaggot just labeled them, and then this schizo label started it's own "journey"

>> No.15453128

>>15452954
you are such an idiot it hurts
please stop posting here

>> No.15453133

>>15448888
HAHAHAHAHAHAHAHAHAH OHOHOHOHOHOH
https://www.youtube.com/watch?v=0KRFRcjoW1s

>> No.15453172

>>15453128
you mad, vaxxie?

>> No.15453264

>>15453172
shill, you are here for our amusement

>> No.15453516

>>15452426
Funeral services are a very lucrative business.

>> No.15454905

>>15448888
Checked and bumped

>> No.15455734

bump

>> No.15456586

bump