Cause of alzheimers etc.

[ImmortLarp !!k43pCIvqmkR No.11217048]

Copper was labelled a toxic hevy metal in error. It is a necessary nutrient. When a protein is missing a copper ion where it's supposed to be, it's prone to collapse, causing amyloid diseases like alzheimers. (this is also the reason why copper bowls is needed for good quality whipped eggs, since it fills up the missing copper sites) See the amounts used in animal feeds, human medicine got the numbers almost certainly wrong. The difference is so massive the EU restricted the concentrations to 150mg/kg feed, since the amounts used were deemed toxic to the environment.

[Anonymous No.11217065]

>>11217048
I've read that the lack of the enzyme choline acetyl transferase might be a cause. What about that?

[Anonymous No.11217200]

>>11217065
That may only be a consequence. Many enzymes do need copper to function, but as far as I know, choline acetyltransferase is not among them.

[Anonymous No.11217204]

>>11217048
>Copper was labelled a toxic hevy metal in error.

Dose makes the poison

[Anonymous No.11217206]

>>11217048
alzheimers is a symptom of aging.

[Anonymous No.11217207]

>>11217206
No it's not.

[Anonymous No.11217212]

>>11217207
yes it is. the people who don't get it die of other things before it takes root.

[Anonymous No.11217213]

>>11217212
So it would technically always happen to old people?

[Anonymous No.11217215]

>>11217213
no, because for plenty of old people they die of other things before alzheimers develops.

[Anonymous No.11217216]

>>11217215
I meant in case they don't die

[Anonymous No.11217219]

>>11217048
So how do I increase my copper intake?

[Anonymous No.11217220]

[Anonymous No.11217226]

>>11217216
yeah, i know there is a meme floating around that dementia is separate from aging but i think the model where we consider cancer, alzheimers, etc a normal part of aging makes more sense given the prevalence, development ages, and mechanism. it's not like infection. this is the body running it's "natural course".

[Anonymous No.11217848]

>>11217048
probably this ''

[Anonymous No.11217856]

>>11217226
>vast majority of people eat a variation of the Standard American Diet
>chronic degenerative diseases rates (diseases of affluence) are immense
>hurr durr it's the natural course of the body when it ages

[Anonymous No.11218925]

>>11217219
Use copper pipes.

[Anonymous No.11218989]

>>11217048
I have never heard about copper being toxic.

[Anonymous No.11218993]

>>11217048
>alzheimers

[Anonymous No.11219001]

>>11218993

[Anonymous No.11219002]

>>11217856
>alzheimers is uniquely american phenomenon
>aging isn't accumulation of damage that lead to conventionally labelled diseases
>human biology is perfect we just need to eat right and it'll just werx
>it's not like evolution took the path of least resistance optimizing for reproduction instead of individual survival for its precious gene propagation system
if that the hurphill you want to die on go ahead.

[Anonymous No.11219005]

>>11219002

https://journals.plos.org/ploscompbiol/article/figure?id=10.1371/journal.pcbi.1006165.g004

[Anonymous No.11219013]

>>11217212
most people dont develop alzheimer

[Anonymous No.11219729]

>>11218989
>I have never heard about copper being toxic.
It seems to be a common myth that started to appear what I could found maybe 50 years ago. In the western medicine at least. There are even laws regulating it and it's hard to get cookware that isn't lined, unless it's for purely decorative purpose. But as far as I know, it was common to even make jams in copper pans. I in fact couldn't find where the myth came from, it seems to be a complete mystery, it seems it just appeared out of nowhere.

[Anonymous No.11219731]

>>11217048
please don't do this you'll summon the earth metals lunatic

[Justin Ramsey No.11219733]

Stop pinging the radiator.

[Justin Ramsey No.11220086]

Complete profile of the type of cop that would moderate girl hangouts by an unknown young male. Alt timeline?

[Justin Ramsey No.11220091]

Long Beach is guilty! Relay his location happened at the following houses.

[Justin Ramsey No.11220111]

Does a book detailing all the coveted up crimes involved with my case exist?

[Justin Ramsey No.11220123]

This is how fucking stupid some people in 2019 are. They wanted “Ramsey guilty” on the cover of a newspaper. Who?

[Justin Ramsey No.11220125]

I have done nothing to no one.

[Anonymous No.11220228]

>>11219729
>>11219729
copper toxicity is not a "meme", it is well-described at higher doses and it is severe. low doses are the issue. But any skeptical person should keep in mind that we used cookware and plumbing and even FOOD made with lead for centuries before its toxicity was understood. Similar case with mercury. These sorts of poisons can be very statistically subtle because the required exposure is typically long-term. All the more so with copper where people appear to have developed an immunity to low doses -- though if we don't even understand this mechanism, how could we pretend to understand its flaws?

[Anonymous No.11220290]

>>11220228
But copper is used in much higher doses in animal feeds. Not only it isn't toxic, it has beneficial effects. It almost appears as if there was a decimal point error in the human RDI. In any case it doesn't seem there were any notable human poisoning cases either. The dangerous effects of lead were known since the antiquity.

[Anonymous No.11220299]

>>11220290
>copper is used in much higher doses in animal feeds
Nobody cares if a cow experiences declining cognitive function in old age.

[Anonymous No.11221139]

>>11220299
You still want the nutrition to be as optimal as possible: https://edepot.wur.nl/336471

[Anonymous No.11221758]

>>11221139
there is no guarantee that optimal feed for meat is the same as optimal feed for cognitive longevity

[Anonymous No.11222705]

>>11217048
Mix of a couple things, one of which is reduced carbohydrate metabolism, as is evidenced by supplementing glucose w/ ketones as a source of fuel

[Anonymous No.11222706]

>>11222705
Reduced carb metabolism caused by can't remember

[Anonymous No.11222710]

>>11222706
Sounds like a thing mitochondria would fuck up on

[Anonymous No.11222733]

>>11222710
Yeah but y tho

[Anonymous No.11222738]

>>11222733
Because mitochondria replicates very quickly and has a high change to cause defects and because it causes free radicals when it creates energy.

[Anonymous No.11222756]

>>11222738
Aye perhaps
I've seen it dubbed type 3 diabetes so it may also be insulin resistance

[Anonymous No.11222766]

>>11217048
>copper water pipes are still a thing

[Anonymous No.11222797]

>>11217048
>(this is also the reason why copper bowls is needed for good quality whipped eggs, since it fills up the missing copper sites)
there aren't "missing" copper sites, in fact the copper is interfering with normal protein function. the copper blocks disulfide bonds from forming

[Anonymous No.11222798]

isn't it the copper salts that are the real problem?

[Anonymous No.11224486]

>>11222797
There are places in the protein that require copper to hold them together, otherwise the protein isn't stable. (other metals can bind to those sites as well, but they won't make the protein more stable) It doesn't block the protein function, it prevents its collapse and denaturation. And the same creates amyloid plaques, the proteins are easily disturbed when they are missing their respective metal.

[Anonymous No.11225845]

>>11221758
Yes, but the optimal feed for meat is already at least an order of magnitude higher than what is recommended for humans.

[Anonymous No.11225900]

>>11219729
>it seems it just appeared out of nowhere
it seems people forgot where it came from
hehe

[Anonymous No.11227536]

>>11217048
>>11217048
>in error
it wasnt in error goy, we cant just wash away our precious metals!

[Anonymous No.11228325]

>>11217048
I blame mass Trace amounts of aluminium in the average diet.

[Anonymous No.11228465]

Just smoke the herb man.

[Anonymous No.11230081]

>>11228325
Probably not that important.

[Anonymous No.11230155]

>>11228325
Could the two be related? Like aluminium occupying the places usually occupied by more benign copper?

[Anonymous No.11230962]

>>11230155
It must be specifically copper. (at least for some proteins) Iron or zinc will be just as detrimental as any other metal, the additional effect of aluminium must be minimal.

[Anonymous No.11233089]

>>11217226
>http://sitn.hms.harvard.edu/flash/2019/oral-bacteria-may-responsible-alzheimers-disease/

You don't know anything about the last discoveries, just stop posting about it

[Anonymous No.11233221]

>>11217048
Copper IS toxic in excess, a lot of beneficial elements are toxic when there's too much of it in the body.
See Wilson's Disease.

>>11217206
A decline in cognitive functions is part of aging, not Alzeimers or Lewy body dementia or any other dementia type.