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/sci/ - Science & Math

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10100142 No.10100142 [Reply] [Original]

/sci/, I need your expertise here. What are the odds of a major defect at birth with a 37 yr old woman? I'm 36.

>> No.10100149

>>10100142

At age 20, 1 in 1,441
At age 25, 1 in 1,383
At age 30, 1 in 959
At age 35, 1 in 338
At age 40, 1 in 84
At age 45, 1 in 32
At age 50, 1 in 44

Paternal age has a much less relevant effect than maternal age

>> No.10100162

>>10100149
>At age 50, 1 in 44
>44
why

>> No.10100168

>>10100162

dunno, probably sampling bias, maybe it gets asymptotically stable

>> No.10100175

>>10100162
Hidden variable in the data due to menopause

>> No.10100192

>>10100149
ty based /sci/entist

>> No.10100339

>>10100149
why is this the case?
what happens to women that they get worse at producing healthy children

>> No.10100356

>>10100142
80% chance of crippling autism.
Your son will probably be a shitposting loser virgin.
Your daughter might be a total bimbo slut who smokes weed with chad.

>> No.10100367

>>10100142
It increases with every minute she doesn't have a bun in the oven.

>>10100339
The body has to create another body inside it. Evidently, that is a really complicated thing that is hard to do, especially when an older body is attempting it.

>> No.10100653

>>10100339
Women produce all of their oocytes during gestation, they age with the woman

>> No.10101463

>>10100142
Just a get a surrogate mother. If the child doesn't look like you or its black or some shit, don't worry about it, you should be proud your a parent now.

>> No.10101488

>>10100149
Holy shit. I knew about the wall but holy shit. I didn't know it was so bad after 40.

>> No.10101494

>>10100142
Don't expose your child to any wireless devices prenatally or otherwise.

It's a bad time to be having children.

>> No.10101510

>>10101488

there's early menopause, that's why numbers drop so much post 40

>> No.10101513

>>10101494
>>>/x/ is that way pseud

>> No.10101522

>>10101488
I think one hypothesis is that all eggs are suspended in meiosis, so the chromosomes are stuck in this state where they're tethered by cytoskeletal elements until sperm hits and they can complete the process. The process starts during the woman's own development in the womb. So for like 40 years you have these tiny cellular skeletal arms just holding on and saying "we just need to hold on a little longer guys" and past a threshold they just snap. Chromosomes can't segregate correctly and you end up with trisomy etc

so like it probably varies but yeah 35-40 seems to be a major threshold and it only gets worse from there

>> No.10101525
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10101525

>>10101513
You're the pseud, layman. Don't talk about what you don't know about.

Now quiet yourself. The point is to inform a man about a source of sterility and birth defects in his future child, not give you a platform where you say the thing you think you're supposed to say, then look around to see if you got your social credit.

>> No.10101530

is it defect / no defect or is it a spectrum and the child has bigger chances of being a low iq retard ?

>> No.10101539

>>10101530

complex question.
do you mean reduced mental capacity due to neurological damages induced by advanced maternal age (premature birth, etc)?

>> No.10101575

>>10101539
exactly

>> No.10101577

>>10100142
This is what abortion is for.

>> No.10101617

>>10101575

well yes, as older a woman gets the less efficient her body is, this reflects directly into faetus blood supply, immune system, placental development, etc.

>> No.10101619

>>10100149
Citation please.

>> No.10101647

>>10101619

about the trisomy 21 rates or the paternal age effect?

>> No.10103393

>>10100142
>>10100149
These shouldn't scare you, OP. There's screening for risky pregnancies and they can detect when shit goes bad. But at 37 chances are that you'll have a pretty healthy baby.

>> No.10103427

>>10100142
>mother had me at 41
>father was 48
no wonder I was born a brainlet

>> No.10103431

>>10100142
This also is influenced by overall health and nutrition on the mothers side.

>> No.10103447

>>10100142
It skyrockets after 35

>> No.10103455

>>10103427
I also seriously think I have Klinefelter's, even though she had an amniocentesis.

>> No.10103526

>>10100142
Just adopt a cute Russian or Chinese kid

>> No.10103678

>>10103393
>But at 37 chances are that you'll have a pretty healthy baby.
Not nearly as healthy as a couple in their mid 20s though. You're setting your kid up to be inferior even if they don't have major defects.

>> No.10103690

>>10100142
it doubles...
from 1% to 2%

>> No.10103696

>>10100142
Zero chance. We are in 2018, we have good medicine, good tech and good psy