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/sci/ - Science & Math


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9821103 No.9821103 [Reply] [Original]

Not my major. A question is keeping me hazy for days.

1. Suppose a newborn baby's biological parents totally died and disappeared. That kid doesn't have any kind of blood relative either.
2. No photograph, no govt record, no specific data available. But superior futuristic dna/related tools are so available.
3. Now, when he grows up he thought that he would find out what his parents used to look like analyzing his own genetical ingredients. He knows that half of 23 pairs of chromosome comes from father, rest half from mother. Is it possible to determine his parents dna /genetic ingredients?
4. Suppose again, he somehow managed to determine their dna or something, can he recreate his parents in incubator?
5. Before 4, please answer 3.
6. TIA. Bbl

>> No.9821113

You could determine whether a few chromosomes came from the mother and father, as certain genomic regions will be differentially methylated depending on whether they originated from the egg or the sperm.

However, this is not true of all chromosomes. Furthermore, you certainly couldn't determine the mother or the father's whole genome because you only have half of their genetic info. You know nothing about the other half of their genetic info.

>> No.9821119

the father's mtDNA is irretrievable

>> No.9821964

>>9821113
>>9821119
Thanks for answering and a bump.

>> No.9821998

>>9821103
3. You know your Mitochondra came from your mother.
4. Your genes are a general blueprint. During the embyonic stage of development a thing called segmental periodicty occurs. A good analogy is making a tie dye t-shirt. The genes tell you roughly where to place the rubber bands, but once the dye is added entropy reigns. Two white t-shirts with the same band locations will look roughly similar, but the blueprint does not dictate where each molecule will be placed. Add in timing variations due to differences in heat, plus lots of other stuff and get a product which is different.

>> No.9822741

>>9821103
The fuck do I know. Clicked for feets.

>> No.9822808

>>9822741
Lol feetfag

>> No.9823462

>>9821103
>is it possible to determine his parents DNA
no, hypothetically one half of each if the computer involved was powerful enough.
>he somehow managed to determine their DNA he didn't
>or something
you're retarded.

>> No.9823463

>>9821119

>the fathers mtDNA
you are also retarded.

>> No.9823488

Even if magically you get his parents genome, it's too difficult to clone yet. All your cells have the same DNA, but every cell type express different proteins, that's because the way that DNA is compacted in each cell. It's quite hard to go back to a stem cell even if you take the nucleus of an specialised cell and you put it in an egg cell. It has been done in the past with Dolly (the sheep), but for every 500 embrios implanted just one became Dolly.

>> No.9823499

>>9821103
He wouldn't be able to since he's only getting half of the chromosomes from his parents. So half of the information needed to complete his parents genome isn't there. Keep in mind the genome undergoes recombination so all the genes' locations are moved around in their respective chromosomes. On top of not having the genome information he wouldn't know what type of epigenetic modifications his parents had. No chance to recreate his parents.

>> No.9823507

Not really

You couldn't get a complete genome for each parent

>> No.9823753

>>9823462
You blind? I said in the first line that I am NOT mejoring in genetics.

>> No.9823938

>>9823463
Men have mitochondrial DNA too, they just don't pass it on.

>> No.9823991

>>9823938
they have their mothers mitochondrial dna thats why its not passed on

>> No.9824816

>>9821103
post more feets

>> No.9824875
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9824875

>>9824816
ok feetfag

>> No.9824888
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9824888

Is this a Jezebel thread now?
>>9824816
>>9824875

>> No.9824903
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9824903

Stay on topic

>> No.9824937

If you were able to get the dna of your parents from your dna, you would also be able to get the dna of your grandparents from your parents and so forth. Does it sound plausible to you that your dna contains the dna of every single one of your ancestors?

>> No.9824938

You have got 46 chromosomes. 23 from your father, 23 from your mother so you know the exactly half of your parents genes.

>> No.9824951
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9824951

>>9824937
I wish if that kind of data were retrievable! Then I'd clone my female ancestors and ....you know the thing ;D

>> No.9824994
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9824994

>>9824903
>>9824951
tempting

>> No.9825165
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9825165

>>9824994
Not really

>> No.9825192

>>9824938
You would never be able to get what it was exactly due to random mutations that would occur throughout the child's life and also the mutations that would occur during the parents meiosis.

>> No.9825224

>>9821113
methylation patterns are reset in gametes.

>> No.9825392
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9825392

>>9825165
PLEASE

>> No.9826126

>>9821103
3, No, because he only has access to 50% of his parent genetic material (one half of each of their pair of chromosomes)
Further, other than sex chromosomes these undergo recombination in meiosis so will be slightly different in parents.
However, youd be able to accurately measure you fathers Y chromosome DNA and your mothers mtDNA

4. assuming he has their genetic code, no. He basically has the cellular master instruction books. This is already altered upon birth by epigenetic marks and then gene expression is further changed by environmental interaction in the womb (gene expression early on is also works a little randomly). So, this is basically saying, although he would create clones, the environment has not been controlled for, so they would be different (e.g. no way of knowing that mother was grown in a starving grandmothers womb that later effected her gene expression)

>> No.9826502
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9826502

>>9826126
Thanks for replying, 4 is sorta interesting

>> No.9826506

>>9821113
There are also DNA mutations (which is why there is such thing as evolution) : The kid won't be a perfect mix of his parents.

>> No.9826920

>>9821103
>>9824903
>>9825165
Good Taste

>> No.9827768
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9827768

>>9826920
Yeah, I know.