/sci/ - Science & Math

>>3984399
What is the most highly cited paper that you propose to put in the reference section of your proposal?

Ask someone who should be doing 3rd year QM homework anything.

I, too, am procrastinating.

And depressed.

So very depressed right now.

what is your future wife's major/ degree?

I hope your not breeding with inferior genes.

>>3984410

probably http://www.cell.com/abstract/S0092-8674(06)00976-7

>>3984421
same.

Lost all joy in learning, gf dumped me, and I missed my workout today for the first time in months. Time will fix the first 2, not being a bitch will fix the third.

What is your problem friend?

>>3984426
>biology
>2011

>>3984445
>implying this isn't the greatest time to be a biologist

>>3984451
but
>biology
>hard science

>>3984452
>implying

do what you love. If the whole world was physicists and mathematicians it would suck.

besides regenerative medicine is much cooler

I'm not a biologist, but I'm quite interested in stem cell research.
I mean, I don't really know anything about it, but I'm interested in what it might lead to, and as such plan to investiaget it further.
What will your potential research concern? Explaining this will make me happy, and hopefully coax some work out of you!

>>3984457
implying making photo-luminescent mice is love worthy.

>>3984475
that isn't what I do, but
>implying you don't want glowing pets

>>3984474
the title of my project is "Differentiation of Human Pluripotent Cells and Fibroblasts to Region Specified Glial Progenitors"

>>3984426

This looks familiar... Can't remember the context I looked at it in before, though.
So, I guess we can assume you're doing some kind of research with stem cells. Which organism are you using?

Ask someone, whose essay is due next week and hasn't started it, anything.

>>3984492
That is the Yamanaka paper. Reprogramming differentiated cells back to stem like states. Ever heard of iPS cells? That's this paper.

Also I'm using mice and human embryonic stem cells.

I bet OP is EK

>>3984487

Question answered. Humans. Did your study involve obtaining the tissue from volunteers, or were you using tissue supplied from some other place which obtains the tissue?
So you're trying to figure out how to coax neuronal cells out of stem cells, then?

>>3984514
>>3984514
No I didn't obtain any tissues. We have skin samples from patients and the embryonic stem cells we use are the ones that were isolated by the government a long time ago.

and I'm trying to coax them into glial cells which you could classify as neuronal, but they aren't neurons. That's a bit of a simplification, but I'm doing other stuff also

>>3984502
>there is only one person in the entire world that does anything with biology, and her name is EK.

>>3984499
That's the induced pluripotent stem cells? I think I must've heard about it on NPR, and probably in Scientific American. Pretty exciting stuff.
Do you find it annoying that the US government has essentially banned all work with embryonic stem cells? And do you find it interesting that the heavy restrictions on stem cell research has forced the field into inducing these cells?

>>3984528
Okay. I only took one class where we even discussed brain physiology, and that was a while ago. I'm assuming glial cells are some kind of differently specialized tissue than regular neurons.

Is this your research proposal, or is it a grant proposal that you're writing?

>>3984529
>>there is only one person in the entire world that does anything with biology, and her name is EK.

it was worth a shot. I'm trying to freak her out

>>3984529
The US gov't hasn't banned all use of hESC though. Some dickhead researchers who use adult stem cells tried to get an injunction and get it banned but it was overturned/denied. And hESC for now are the gold standard when it comes to this research. We aren't totally sure EXACTLY how identical to hESC cells are to the iPS.

There were 3 papers published last year calling this into question

http://www.nature.com/nature/journal/v471/n7336/full/471046a.html

>>3984540
glial cells have typically been thought of as the "support cells" of the brain, only aiding neurons, but they make up 90% of the human brain.

research proposal for my PhD written in the style of an NIH grant


>>3984544
I'm not EK

>>3984552
>>3984547

Thanks for the info.
Have a good night. =) Good luck with your proposal.

>>3984547

from what i recall, iPS are less prone to neoplasticity than hESCs, but the don't thrive as long and tend to get all wacky before too long. and the phenotypes don't quite match what they ought to?