[ 3 / biz / cgl / ck / diy / fa / ic / jp / lit / sci / vr / vt ] [ index / top / reports ] [ become a patron ] [ status ]
2023-11: Warosu is now out of extended maintenance.

/sci/ - Science & Math

View post   
File: 626 KB, 890x897, 1586270296496.png [View same] [iqdb] [saucenao] [google]
15263580 No.15263580 [Reply] [Original]

Is there potential in mRNA drugs for anabolic doping? Instead of injecting testosterone to activate androgen receptors and a cascade that ends with ribosomes synthesizing muscle proteins from mRNA, you just inject the mRNA directly (with some sort of delivery mechanism to target muscle cells). Or is this doomed to failure?

>> No.15265665
File: 40 KB, 400x297, mighty-mouse-gene.jpg [View same] [iqdb] [saucenao] [google]
15265665

>>15263580

Myostatin siRNA ... so long as you don't mind that it'll likely give you lots of cancer down the road.

>> No.15265702

>>15265665
bit of garlic, bit of basedsauce, some sesame oil, hhggggggn this mice would taste so good

>> No.15265733
File: 153 KB, 700x980, dinner_is_prepared_darling!.jpg [View same] [iqdb] [saucenao] [google]
15265733

>>15265702

>t.

:D

>> No.15266153

>>15265665
It's crazy to me that Myostatin-inhibiting drugs haven't really been developed yet. People are already more than willing to fuck up their bodies for easy gainz through other means, surely there'd be a market for a drug that could double your muscle mass.

>> No.15266155

>>15263580
>Is there potential in mRNA drugs for anabolic doping?
Yeah absolutely. There's potential with gene therapy type tech to do pretty much anything. Good luck synthesizing your own mRNA THOUGH.

>> No.15266276

>>15266155
Yeah, obviously genes are the drivers of almost everything happening in the body, but i was thinking if there are other mechanisms happening alongside muscle protein synthesis that is necessary for the process to be effective/safe.