/sci/ - Science & Math

>>14799813
>why did science have to be ruined by covid vaccine shitflinging.
It's the culmination of years of market capture by pharma companies. You haven't been allowed to hear any truth from them for decades but didn't notice because it was never forced on you in ways that were visible.

>>14799821
Thanks for proving my point. Everything is some big scheme, nothing just IS anymore.

>>14799813
Because science isn't real, it's a tool used by politicians who are controlled by the illuminati and globohomo

>>14799829
You're just being forced to notice it now. You want to live in a bubble where you can believe this wasn't happening, but everyone in the healthcare industry has known for years.

Osteoporosis treatments, bone density scanners, Gardasil, Statins. Lies have been peddled for a long time. As a normie this one event showed you how bad things really were, and you're desperate to have the genie put back into the bottle.

>>14799813
Lead deficiency schizophrenia.

>>14799833
>>14799846
Fuck off /pol/tard.

>>14799846
You're no better, alt-sci is just as fucking retarded as any imaginary megascheme you think the world runs on

>>14799821
>muh hidden truth
Statistically, you have a higher chance of getting eaten by a shark than dying from a heart attack after getting vaccinated.

But I wouldn't expect a science denier to understand this.

>>14799868
Fuck off science-worshipping normie, you are a slave to your own matrix

>>14799906
And you're no different, neognostic

>>14799813
>why did science have to be ruined by covid vaccine shitflinging.
Do you believe that public policy should be scientific? Do you believe that credibe experts should establish government policies based on high-quality peer-reviewed scientific studies? Do you believe that modern society is too complex and technologically advanced for social policies to be dictated by the sensibilities of the poorly educated laymen? Well, there's your answer. You bought into this midwit propaganda and now there will be no science, only politics.

>>14799917
I'm not a gnostic you actual fucking retard, go suck the cock of your Elon Musk and other globohomo politicians you loooove so much for sure

>>14799919
I believe science just is. And that it has as much sociopolitical importance as your preferred scent of car tree air freshener

>>14799923
You believe you have a secret knowledge that frees you from an illusory world created by ineffable evil omnipotence. You're gnostic

>>14799924
Even if you're not personally complicit in it, I gave you the real answer.

>>14799933
Gnostic

>>14799813
>Studies show 4chan users are right-wing assholes.

>>14799919
>Do you believe that public policy should be scientific?
Who gives a shit?
>Do you believe that credibe experts should establish government policies based on high-quality peer-reviewed scientific studies?
They don't, politicians (who are just as unknowledgable as you) do that
>Do you believe that modern society is too complex and technologically advanced for social policies to be dictated by the sensibilities of the poorly educated laymen?
The fuck are you talking about?

I wish /pol/ was banned

>>14799939
>study: open testimony from 4chan users

>>14799813
normies and women and etc. infected science. Focus on the old style white scientists and youll find the way. Fuck modern science. Fuck women. Fuck normies. Fuck the fags that reply to me complaining that their nigger infested studies are valid.

>>14799821
>>14799846
>>14799906
>>14799919
>>14799868
>>14799873
>>14799899
>>14799917
>>14799933
>>14799945
If you accept the official narrative blindly, without any scrutiny, but subject all new ideas to exhaustive scrutiny, you're a sheep.

If you accept new ideas blindly, but subject the official narrative to exhaustive scrutiny, you're a sheep.

A real, meaningful pursuit of knowledge can only come from a willingness to scrutinize all ideas, regardless of origin. You must be willing to search for evidence and continuously evaluate all theories, including the ones you cherish, to see if they make sense in light of the evidence.

>>14799955
This
Something which both normies and schizos alike will never be able to do

>>14799955
Go tell that to Big Bang Enthusiasts, they do seem to be heavy on cope right now after their theory was scrutinized by a based telescope

>>14799955
Nigger there is a thread right now discussing how the idea of lead toxicity is a globohomo conspiracy to make us sick by depriving us of nutritional lead.

There aren’t wolves in sheeps clothing, there are sheep mutually pretending to be shepherds while calling other sheep secret wolves. There are no shepherds and there are no wolves; and if there were, they'd both be watching this mess utterly dumbfounded

this thread really attracted all the lunatics huh

>>14799987
You are absolutely fucking retarded, this is the equivalent of a cow in a farm saying "look at the humans over there, they are giving us free food and water everyday, they take care of our wellbeing and love us, yet there are conspiracy theories that they're actually doing all of this just to slaughter us! This is such an absurd idea!"

I really do pity your situation, it's hard to exit such a matrix, but hopefully once you do, you don't look back

>>14800001
Now imagine what the world looks like from the other side, because guess what! You election tourists are no fucking different from eachother. You just think your side are perpetual underdogs in a cosmic foreverwar. You have no God, only corporeal demiurges.

>>14799945
Why are you losing your mind?

>>14799813
It sounds like you are insane.

>>14800021
Because truth has been raped and left for dead by politics. Question the /pol/tard "science?" You're a libshit redditor. Question libshit reddit "science?" You're a dangerous bigoted nazi.

There is no middle, there is no objective reality, because EVERYONE AND EVERYTHING is now so heavily dependent on strict orthodoxy which can never be challenged because otherwise you're just brainwashed by the Bad People and not a Glorious Enlightened One

>>14799955
>blabber about scrutiny
>can't even run an experiment

Shut the fuck up fag

>>14800038
Why are you losing your mind and what does it have to do with my post?

>>14800042
I told you why

>>14800044
Why are my posts making you lose your mind? I'm not arguing any politics.

>>14800046
>I'm not arguing any politics.
>You bought into this midwit propaganda and now there will be no science, only politics.

>>14800038
You can cry like a woman, or you can do the work yourself and come to truth.

Which fate will you choose?

>>14800065
That's not a political statement. That's an objective observation about what happens when you politics "scientific": science becomes political.

>>14800069
Yeah and you certainly know everything don't you? I'd rather pray for your slow and painful death

>>14800082
Cry like a woman it is then. Remember, you could have put in the work to rise above the crowd, but you chose not to.

>>14800086
>>>/pol/

>>14800086
>you could have put in the work to rise above the crowd
"Work" for who exactly, oh, those bureaucrats in the government who want me to be a useful bootlicker in exchange for taxes?

>>14799928
It's not secret knowledge, it's just being able to read studies and having real world experience in healthcare. Everyone working in the industry knows what's happening and they're telling you frequently, you just don't listen.

>>14800379
>having real world experience in healthcare
Nurses are fucking retarded though

>>14799813
It's simple. Don't trust scientists. Don't trust government. Don't trust 'experts'. They are all ruthlessly utilitarian, which means at best they will lie to you to 'reduce harm', even if it leads to your death. In reality they are that but also with numerous layers of corruption, ideology, cowardly nature, and outright malevolence.

Don't trust scientists. Ever.

>>14799813
pussy kys

>>14799813
by the way, you should get vaxxed, retard

>>14801016
>>14801021
Why are you going insane? Vax on the brain?

>>14799829
always was

>>14801003
So what about the faggots shilling supplements as alternatives to medicine just to make a quick buck off schizos?

>>14801106
use your God-given discernment, my nigger

>>14801115
And doing THAT tells me people like >>14801072 are nutcases that think they're the protagonist of the world and everything is SPECIFICALLY against them as an individual and if it doesn't reinforce their preconceptions, then it MUST be a massive scheme to push some unknowable "Step 3: Profit" mastermind plan that doesn't even make sense.
Like if the vaccine is some master plan against the masses, why would the biggest thorns in the side of that plan be effectively safe from it? That makes as much sense as Hitler talking about those nasty Jews and Poles but making sure the highest authorities in the Reich were Jews and Poles actively killing off Germans while still saying that soon the German Race will triumph over the untermench. It makes no sense.

>>14801115
This. People need to think for themselves.

>>14801145
>Like if the vaccine is some master plan against the masses, why would the biggest thorns in the side of that plan be effectively safe from it? That makes as much sense as Hitler talking about those nasty Jews and Poles but making sure the highest authorities in the Reich were Jews and Poles actively killing off Germans while still saying that soon the German Race will triumph over the untermench. It makes no sense.
They just hate you and want money. It's not about politics.

>>14801152
>They just hate you
No they don't dipshit. They're indifferent at best, Messiah complex at worst.

>>14801163
If they were indifferent they would behave differently when caught in a lie.

>>14801184
What's the difference between a lie and a Messiah complex you genuinely believed in that proved to be false? Or even a Messiah complex where you just keep wanting to be on the Right Side over and so you just cling to whatever is currently correct because you don't want to be wrong?

"The Elites" are as irrational and human as the plebs, you're genuinely no different. Klaus Schwab is the exact same person as the onionfuckers who suck off every retarded idea he has.

>>14801145
if the answer doesn't make sense, then you should question your assumptions

>>14801239
What is "making sense?" A=C, B=C therefore A=B; but then if Red Bull is Fuel, and Kerosene is Fuel, therefore Kerosene is Red Bull and you can drink that shit. Is a Wood Duck not a duck because it doesn't quack? Is a whale a fish because "well morphologically it's a fish?"

>>14799813

>>14799899
The odds of someone having a random heart attack are higher than their odds of ever being attacked by a shark.
Is this bait?

>>14801216
This is an interesting thought actually. I read a good article on the idea a while back that I think explains the entire plandemic in a nutshell.

"Munchausen's Syndrome by Proxy on a Societal Scale."

https://kirstenmortensen.com/munchausen-syndrome-by-proxy-on-a-societal-scale/

>>14801627
Prove it. Also statistics don't mean what you think they mean

>>14804474
Why are you so religious about a shot that doesn't even work?

>>14805226
I could ask the same of why you care so much about a placebo

>>14805437
It's not a placebo, the intended effect is to harm you.

>>14799899
>Statistically, you have a higher chance of getting eaten by a shark than dying from a heart attack after getting vaccinated.
There are millions of shark attacks each year on your planet? LMAO!

>>14801146
>People need to think for themselves.
"Aint nobody got time fo dat!" meme

I find it funny that /sci/ supports culling the population but NOT in the way that elites have gone about it.

>>14799813
>delete the internet
Problems gone

>>14805884
Evay-one got they own methods yo!

I’ve never heard a compelling or even coherent argument for why governments would poison their own people.

Most governments are bottoming out at fertility rates. They want more people not less. It makes no sense for why Russia, China, America, Europe, India, and Japan would kill off everyone loyal enough to get a shot and too wide scope to be like a profit motive thing.

Idk I just don’t get the angle.

I had to get the vaccine plus a booster for my job (work in medicine) and I’m fine. There haven like 3 or 4 “death dates” and I’ve survived all of them.

>>14806091
The first country to ban birth control and outlaw the social media sector of the internet will rule the 21st century. It’s only a matter of time until then

>>14806119
Sounds like China.

>>14806114
>I’ve never heard a compelling or even coherent argument for why governments would poison their own people.
Then you are probably not smart enough to listen, or even read a children's book on history.

Hard to believe anyone would be THAT dumb, so you are a glowie.

>>14806119
brainlet
>ban birth control
incentivize having babies
penalize not having
>outlaw social media
strictly limit it's use
>>14806135
Do not be so quick to dismiss NIGERIA!

>>14806146
>Do not be so quick to dismiss NIGERIA!
It would rule then, if you got rid of the nigerians and filled the country with nordic supermen.

>>14806137
>Then you are probably not smart enough to listen, or even read a children's book on history.
Okay.
>>>/his/>>13878157

>>14799833
>it's a tool used by politicians who are controlled by the illuminati and globohomo

>>14799813
The best thing you can do is not care.

>>14801627
>Is this bait?
It's Shark-bait.

>>14805226
>Why are you so religious about a shot that doesn't even work?
picrel

>>14806114
>I’ve never heard a compelling or even coherent argument for why governments would poison their own people.
If your government is infiltrated by foreigners, then the government might not have your best interest in mind.

>>14806385
>ANY government NEVER has your best interests in mind.
FIFY
They are your slave-owners.

>>14806137
>Hard to believe anyone would be THAT dumb
Glowies certainly can.
>so you are a glowie.
Definitely a non-zer0 chance that's true.

>>14806392
This is a midwit-take.
There are people who get into "Government" for non-malevolent reasons, but it just happens to attract the worst kinds of people as well.

"No Rules, Anything Goes" Anarchy just doesn't exist. Most people are interested in working together so they can divide up tasks, and accomplish more with less work.
But every once in a while, some people are born who believe "contributing" or "working" is only for retarded sheep.

Government isn't inherently bad, it's just bad when Sociopaths are making important decisions.

>>14806382
Picrel is a schizophrenic jumble of nonsense made by someone who lives in a world where Christianity is true...EXCEPT for all the parts actually involving God being the ultimate victor above all things.

>>14806394
>he disagreed! He a fed!!!!
You don't even know what glowing actually is. If anything, feds would ENCOURAGE antivax schizo theories so that you snap and they can use that to further an agenda against antivaxing. The fact anyone disagrees with you is already proof theyre not feds

>thread filled with projection in order to pigeonhole your interlocutor and associate them with obviously crazy people
It's as simple as just addressing what people say instead of trying to fit them into a category, how hard is that? You shouldn't a priori "trust the science" or a priori trust the opposing camp, you should apply a healthy skepticism to everything. The only people who should be mocked and dismissed are the ones who blindly trust any one position.

>>14799970
True but they don't have a monopoly on copium. The past two years have really done a number on the IFLS! crowd and the normie masses. Wish there was a way to buy stock in copium because we could all get rich off of the high demand for it.

>>14806119
what country? You talking about the US? because if so you're wrong, the courts never banned it.

>this thread
lmao /sci/ got absolutely mindbroken by being proven wrong so many times

>>14807909
Fuck off /pol/

>>14807909
Vaxies will literally never be able to cope properly. They're so mad they were conned.

>>14808218
Vaxxies want everyone else to get in their sinking boat with them. They mad that their enemies were smarter than them.

>>14808451
This is the essence of it. Crab-bucket mentality.

>>14799813
money + science = shit science
politics + science = extreme shit science

https://www.brighteon.com/f96a09e1-e2bc-48b2-9c48-04ae9e3c7549

>>14799919
>>14799945
Science is at its best when it's done with the same seriousness, playfulness and autism of 4chan debating whose waifu a shit.
If you say that public policy should be scientific then that will politicize science and suck all the fun out of it. It means declaring a winner. So I don't want scientific policy.
I want informed-by-science policy. I want the politicians to listen to the debate, and say "having listened to the arguments, this is my personal view. Vote for me".

tl;dr the spike protein by itself can damage endothelial cells and disrupt the blood-brain barrier

https://www.biorxiv.org/content/10.1101/2020.12.04.409144v1
SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2
Lei et al

Spike expression disrupts lysosome function:
https://www.biorxiv.org/content/10.1101/2020.12.08.417022v1
The D614G Mutation Enhances the Lysosomal Trafficking of SARS-CoV-2 Spike
Guo et al

https://www.biorxiv.org/content/10.1101/2020.12.23.424283v1
The SARS-CoV-2 S1 spike protein mutation N501Y alters the protein interactions with both hACE2 and human derived antibody
Fratev

https://pubmed.ncbi.nlm.nih.gov/33328624/
The S1 protein of SARS-CoV-2 crosses the blood-brain barrier in mice
Rhea et al

S1 portion of SARS-CoV-2 spike protein — without the whole virion or genome — triggered growth signals in cultured human blood vessels from the lungs:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827936/
SARS-CoV-2 spike protein-mediated cell signaling in lung vascular cells
Suzuki et al

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827936
SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines
Suzuki et al

https://www.medrxiv.org/content/10.1101/2021.03.05.21252960v1.full
SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: Implications for microclot formation in COVID-19
Grobbelaar et al

https://www.sciencedirect.com/science/article/abs/pii/S0006291X2100499X
SARS-CoV-2 spike protein interactions with amyloidogenic proteins: Potential clues to neurodegeneration
Idrees et al.

>>14809813

https://pubmed.ncbi.nlm.nih.gov/33053430/
The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier
Buzhdygan et al

https://www.sciencedirect.com/science/article/pii/S0925443921001939#!
SARS-CoV-2 spike promotes inflammation and apoptosis through autophagy by ROS-suppressed PI3K/AKT/mTOR signaling
Fei Li et al

https://pubmed.ncbi.nlm.nih.gov/33360731/
Endothelial cell damage is the central part of COVID-19 and a mouse model induced by injection of the S1 subunit of the spike protein
Nuovo et al

Spike stays in lymph nodes:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786601/
Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination
Röltgen et al

spike moves between organs:
https://pubmed.ncbi.nlm.nih.gov/34811493/
Spike protein multiorgan tropism suppressed by antibodies targeting SARS-CoV-2
Brady et al

https://pubmed.ncbi.nlm.nih.gov/35891400/
Potential Autoimmunity Resulting from Molecular Mimicry between SARS-CoV-2 Spike and Human Proteins
Janelle Nunez-Castilla et al

>>14799813
> I can't take it anymore
Is anyone forcing you to visit this shithole?

test

>>14806425
>There are people who get into "Government" for non-malevolent reasons
they don't matter. the biggest and most influential powers have been firmly rooted in the status-quo, even if new entities have been coming and going (see tech billionaires today). But they don't have as much power because the people who already had the most power have never left (their organizations, groups etc... I mean). This isn't a conspiracy, it's simply how competing power structures act and evolve in such a short time-frame (the current status-quo has been slowly building roughly since the creation of banking).

>>14809817
ADCC:
tl:dr any cell expressing the Spike protein will be targeted for destruction by Natural Killer Cells

autoimmune diseases, here we go!

https://www.medrxiv.org/content/10.1101/2020.11.12.20230508v1
Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies
Dufloo et al
asymptomatic SARS-CoV-2 infection elicits polyfunctional antibodies neutralizing the virus and targeting infected cells. - Sera from convalescent COVID-19 patients activate the complement and kill infected cells by ADCC. - Asymptomatic and symptomatic SARS-CoV-2-infected individuals harbor polyfunctional antibodies. - Antibody levels and functions are slightly lower in asymptomatic individuals - The different antiviral activities of anti-Spike antibodies are correlated regardless of disease severity. - Functions of anti-Spike antibodies have similar kinetics of induction and contraction.

https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.202149470
Natural killer cell-mediated ADCC in SARS-CoV-2-infected individuals and vaccine recipients
Hagemann et al
serum samples from individuals that received the BNT162b2 vaccine induced strong CD107a expression by NK cells that increased with the second vaccination and was significantly higher than observed in infected individuals

>>14799955
That just makes you a schizo

>>14809821
Oh, you!

>>14799813
can't believe people are still talking about covid, that shit was years ago. get over it already

>>14809813

So covid is more dangerous than the vaccine, got it.

>>14799813
>I can't know what reality is anymore because it's all forced into a rigid dichotomy
That is the goal of all modern USA-based propaganda. It is designed to confuse and make you incapable of acting. Propaganda wants you to check out of society.

>>14811344
No because the vax exposes you for 10x longer with 2 doses and even more for every further dose. Likelihood of death is exponential the more you take.

>>14804474
>Also statistics don't mean what you think they mean
God your such a midwit it physically hurts

>>14810723
Only fly over country ppl say this dumb shit. It's like complaining about iraq discussion a year after the war started

>>14799899
>science denier
Cool it with the religious language, buddy.

>>14811344
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786601/
>Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination
>Röltgen et al
Imprinting from initial antigen exposures alters IgG responses to viral variants
Histology of mRNA vaccinee lymph nodes shows abundant GCs
Vaccine spike antigen and mRNA persist for weeks in lymph node GCs

https://osf.io/preprints/bcsa6/
>Differences in Vaccine and SARS-CoV-2 Replication Derived mRNA: Implications for Cell Biology and Future Disease
>Mckernan et al
First, the biodistribution of non-specific LNP transfection of mRNAs does not discriminate towards ACE2 or CD147 expressing cell lines as seen with the virus.
Second, the mRNAs are known to have a 2 Proline substitution (K986P and V987P) altering the proteins conformation.
Additionally, the expression levels and duration of these mRNAs may be longer and of higher copy number in many tissues that never experience natural virus infection.
Finally, the pharmacokinetics of injection
30ug- 100ug per injection (90ug-300ug for those boosted) of Spike mRNA equates to 13 Trillion to 40 Trillion mRNA molecules injected in a few seconds with each injection.
If each of these mRNAs can produce 10-100 spike proteins and you have 30-40Trillion cells, there may be a far greater systemic quantity and a much longer duration of spike protein exposure through the vaccination route than natural infection.
Boosters given more frequently than a year will lead to total body accumulation of spike protein and further heighten the risk of disease in organs such as the brain, heart, bone marrow, and immune cells and tissues.

>>14812343
CANCER:
https://www.sciencedirect.com/science/article/pii/S027869152200206X
Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs
Seneff et al
mRNA vaccines promote sustained synthesis of the SARS-CoV-2 spike protein.
The spike protein is neurotoxic, and it impairs DNA repair mechanisms.
Suppression of type I interferon responses results in impaired innate immunity.
The mRNA vaccines potentially cause increased risk to infectious diseases and cancer.
Codon optimization results in G-rich mRNA that has unpredictable complex effects.
these disturbances are shown to have a potentially direct causal link to neurodegenerative disease, myocarditis, immune thrombocytopenia, Bell’s palsy, liver disease, impaired adaptive immunity, increased tumorigenesis, and DNA damage.

tl;dr spike blocks p53-related tumor suppresion at nuclear level, see
https://www.frontiersin.org/articles/10.3389/fmed.2021.798095/full
Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case Report
Goldman et al
ttps://www.sciencedirect.com/science/article/abs/pii/S0046817718301941
TP53 mutations in peripheral mature T and NK cell lymphomas: a whole-exome sequencing study with correlation to p53 expression
Huang et al.
A wide range of TP53 mutations across all exons were identified in peripheral mature T and NK cell lymphomas. TP53 mutation and p53 expression tended to indicate poor prognosis.
https://pubmed.ncbi.nlm.nih.gov/12063435/
The role of p53 mutation in BRCA1-associated ovarian cancer
Rose et al
p53 protein product plays a crucial role in DNA surveillance and repair at the Gap 1-synthesis (G1-S) cell cycle checkpoint

>>14812418
>block your p53 tumor suppressor gene with your vax
>profit
>use technoscience to restore it
>profit
win-win for Big Pharma
https://www.genengnews.com/topics/drug-discovery/therapeutics/immunotherapies/mrna-nanoparticles-restore-p53-function-improve-immunotherapy-response/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828745/
mRNA Nanoparticles Restore p53 Function, Improve Immunotherapy Response
Xiao et al
As p53 loss of function may play a role in immunosuppression, we herein examine the effects of restoring p53 expression on the immune TME and ICB efficacy. We develop and optimize a CXCR4-targeted mRNA nanoparticle platform to effectively induce p53 expression in HCC models.

>>14809813
>>14809817
>>14810663
>>14812343
>>14812418
>>14812424
some day I'll put all these links together in a single doc (but it's over 25000 words so far)

>>14812519

>>14799821
Fpbp.

>>14812519
It's a shame nobody actually tried to refute you. All the shills just ignore when evidence is presented.

>>14811795
except the s proteins produced by the vaccine are locked in a stabilized prefusion conformation so all these studies are irrelevant

>>14813724
Cai et al found that the spike protein sometimes goes from its original "before" shape into the "after" form prematurely, without the virus binding to the ACE2 receptor.

https://www.science.org/doi/10.1126/science.abd4251
Distinct conformational states of SARS-CoV-2 spike protein
Cai et al
>We propose that there are two routes for the conformational changes. One is ACE2 dependent, and allows the virus to enter a host cell. The second is ACE2 independent.
The researchers speculate that having some spikes assume the post-fusion form prematurely may also protect SARS-CoV-2 from our immune system, inducing antibodies that are non-neutralizing and ineffective in containing the virus.

>Our study raises several potential concerns about the current vaccine strategies.
>First, vaccines using the full-length wild-type sequence of the S protein may produce the various forms in vivo that we have observed here. The postfusion conformations could expose immunodominant, non-neutralizing epitopes that distract the host immune system, as documented for other viruses such as HIV-1 and RSV (46, 47).
>Second, the approach to stabilizing the prefusion conformation by introducing proline mutations at residues 986 and 987 may not be optimal because the K986P mutation may break a salt bridge between protomers that contributes to trimer stability. The resulting S trimer structure with a relaxed apex may induce antibodies that could not efficiently recognize S trimer spikes on the virus, although it may be more effective in inducing anti-RBD–neutralizing responses than the closed form.
>Third, considering the possibility that the postfusion S2 is present on infectious virions, vaccines using β-propiolactone–inactivated viruses may require additional quality control tests.

>>14799813

>>14813724
>>14814761
and if you read the pfizer leaks from 2021, it looks like they were aware of this

https://web.archive.org/web/20210305053725/https://www.slideshare.net/enave2609/ss-242999249
>. Three-dimensional classification of the dataset showed a class of particles that was in the conformation one RBD ‘up’ and two RBD ‘down”. This partly open conformation represented 20.4% of the trimeric molecules. The remainder were in the all RBD ‘down’ conformation. Although potent neutralizing epitopes have been described when the RBD is in the “heads down” closed conformation, the “heads up” receptor accessible conformation exposes a potentially greater breadth of neutralizing antibody targets.

>>14801145
>Like if the vaccine is some master plan against the masses
it's not a master plan, it's just money, they just had tried to push mRNA "vaccines" for years but they were shit, this was an opportunity and they did it, they "knew" the solution they wanted and blocked any alternative treatment for Covid, of course the mRNA vaccines turned out to be shit just like they were every other time they tried to push them through proper testing channels

once they started they couldn't stop because the machine to shield the experts from criticism went into full overdrive, it was more important to keep compliance of the people than the effectivity of any measures

best case scenario, the vaccines killed more people than covid, worst case scenario, the vaccines did a lot of damage that will appear slowly

>>14806114
my negro, Biden just came out on tv and said 50% of the population is evil and their votes shouldn't count lmao

>>14801145
You are the carbon they need to reduce. You are not fit for a new world, you and your kind will be gone so thinking humans can rebuild once again.

>>14799917
Reasonable. I'm pretty right wing personally and find it somewhat embarrassing to associate myself with the label given the state of the American right. For the life of me I do not understand why Americans associate environmental conservation with left wing politics. It's downright shameful and there's no good reason for it. I suppose if I were to speculate I'd say the American ethnos has declined to the point that the only meaningful collective cause for the right today is some sort of abstract 'liberty' from the State, and regulatory action is generally interpreted as an imposed tyranny. Even a century ago, I don't think this was such a polarizing partisan issue, Republicans like Teddy Roosevelt even built their careers on protecting Americans wellbeing. One of his big successes was the Pure Food and Drug act, among a number of conservation reforms, work safety reforms, anti trust laws, etc... All this being the case he remained a staunch Nationalist. It's sad to see things have decline so substantially.

>>14814779
>except the s proteins produced by the vaccine are locked in a stabilized prefusion conformation so all these studies are irrelevant
It's more than just money. Gene therapy isthe biggest potential tool for life extension. They're pushing it on people en masse as a human trial to see how the uptake is and get long-term results on the safety of genetically modifying the human body. The only "downside" for them is that a lot of proles may die, but their customers want that anyway.

>>14799899
>science denier

This is cult language. Your mind has been captured.

>>14814779
>it's not a master plan, it's just money, they just had tried to push mRNA "vaccines" for years but they were shit, this was an opportunity and they did it, they "knew" the solution they wanted and blocked any alternative treatment for Covid, of course the mRNA vaccines turned out to be shit just like they were every other time they tried to push them through proper testing channels
>once they started they couldn't stop because the machine to shield the experts from criticism went into full overdrive, it was more important to keep compliance of the people than the effectivity of any measures
>best case scenario, the vaccines killed more people than covid, worst case scenario, the vaccines did a lot of damage that will appear slowly
Best explanation have read yet.
The world's white population became lab rats.

>>14799899
>I wouldn't expect a science denier to understand this.

>>14801145

>>14799813
Scientists have always been professional liars, never trust them.
Read the Bible if you want to know about truth.

>>14799829
Machines will solve it, humans must survive until then

>>14812519
>>14799813
>>14809813
>>14810663
>>14812343
>>14812418

I put a summary of all my shared notes on the vax effects online, let me know if you have any comments on how wrong am I

https://file.io/u1x1aVZeo183


>>14812524
have a (you)

>>14820333
>>14813587
>https://file.io/u1x1aVZeo183
I divided it into categories, for easier reading, but still is quite a task
[VAX INEFFECTIVITY]
[MYOCARDITIS RISK]
[ADE - Antibody-dependent enhancement]
[OAS - Original antigenic sin]
[ADCC - Antibody-dependent cellular cytotoxicity]
[SPIKE PROTEIN - Antibody escape]
[SPIKE PROTEIN - TOXICITY and ACE2 infectivity]
[DIFFERENCES BETWEEN VACCINE SPIKES and VIRUS SPIKES]
[EVOLUTIONARY PRESSURE LEADS TO MORE VIRULENT VARIANTS]
[CANCER - p53-blocking mechanism]
[PRION DISEASES - ALZHEIMER]
[AMYLOIDOSIS - ALZHEIMER]
[VIRAL and VACCINE SHEDDING]
[CELLULLAR SENESCENCE]
[INFERTILITY - placenta, testes, pregnancy, miscarriage, menstrual problems]
[LIPID NANOPARTICLES]
[NEVER STOPS REPLICATING - DNA reverse transcriptase, 3utr 5utr shenanigans]
[OTHERS]

>>14799813
>I can't know what reality is anymore because it's all forced into a rigid dichotomy
Just stop reading internet and this controlled website. Vou will see that nothing ever changes except the things you loose because they plunder you,

>>14820336
>>14820333
Looks like it was deleted
I'll reupload it somewhere else later

>>14811947
Says the /pol/tard

>>14810723
This

>>14806425
>There are people who get into "Government" for non-malevolent reasons
Trump was the first in a couple generations. Look what they did to him.

>>14806425
>"No Rules, Anything Goes" Anarchy just doesn't exist.
Sure it does, it is nature. Humans try to defy nature and impose rules on each other. That causes wars and suffering.

>>14806425
>some people are born who believe "contributing" or "working" is only for retarded sheep.

That is true. Work for yourself and family. If everyone did that, then there would be no suffering or want. Fuck the lazy people who want society to coddle them.

>>14806425
>Government isn't inherently bad, it's just bad when Sociopaths are making important decisions.
It is ALWAYS bad. ALL politicians are sociopathic.

YOU are a glowie/leftist/fascist, we all know that.

>>14810723
>>14821678
Pride-Pox is the latest hotness!

>>14820758
lets see how long this one lasts
SARS-COV2 notes:
https://textup.fr/648248W1