/sci/ - Science & Math

>>12704120
It's literally how all cells differentiate from stem cells into their final fates.

So it's pretty important. But there are problems with the overreaching people were doing on in life transitions being inherited. But a lot of stuff gets fucked and unfucked in developing cells.

>>12704189
Interesting, so I was right to be skeptical of those claims. It sounded like a "too good to be true" homerun for people in the nurture > nature camp and was therefore likely to be politically motivated rather than scientifically motivated.

I don't doubt epigenetics is important, I was mostly questioning the whole "everything we know about genetics is wrong" hysteria I vaguely heard about 10 years ago.

>>12704120
>>12704196
>Is the case for epigenetics overstated
>It sounded like a "too good to be true" homerun for people in the nurture > nature camp
Well, some guy saying that "this guy's great-great-great-great-grandparent was starving, which is why he is low IQ" is retarded. But somone saying "this guy's father was starved during his childhood, which is why he is low IQ" isn't THAT far off.

>I was mostly questioning the whole "everything we know about genetics is wrong"
Yeah you did right. It didn't change that much.

>>12704120
.gg/TJvGnYfknX

>>12704120
It’s legit.

>>12704120
It's completely legit since it's basically the activity of any given gene (+- some splicing), but like...
If you're epigenetically predisposed to obesity, you don't need as much food to survive. If you're epigenetically predisposed to anxiety, you need more mindfulness in your life than others. It is used as an excuse when it shouldn't be.

>>12704120
>>12704196
>>12704256
https://www.zeit.de/2008/25/M-Genetik/komplettansicht
But, but it’s in German. Yes, but just use a translator. Even epigenetics isn’t really much of a thing anymore.
See
>>12701671
>>12688352
We realized it’s way more complicated.

>>12706352
This doesn't even get into the crazy reality of continuous self-organizing systems in cytosol and the like.

>>12706357
Correct, but it‘s hard to explain. Try to make ordinary scientists or interested laymen understand it. If you say there somehow is information in the way the fluids move, you will just provoke blank stares.

>>12704120
Well deserved attention from the public. Focusing mainly on genetics and Epigenetics is the right thing to do if you want to solve aging and disease.

>>12706339
There is no such thing as Epigenetically predisposed, only genetically predisposed.

>>12706386
The best jokes are only for insiders

>>12706822
Indeed.
Would you mind to give your favorite papers on this? I personally don’t really like the term post darwinian, because in a sense it opens many paths to even deeper levels of inheritance. But generally away from this DNA and random mutation centered paradigm. I would be very interested and thank you in advance.

>>12704120
not at all, genetics is an absolute clusterfuck of a field. i think it's less typical for epigenetic stuff to be passed on, but absolutely it impacts just about everything in your body. the sorts of foods your mom consumes while pregnant with you can alter your personality, for example.

as another example, addiction to drugs is a largely epigenetic phenomena. if your limbic system gets a lot of dopamine, it releases a transcription factor called delta-fosB that alters your dopamine receptors, and sensitizes them so that they respond stronger to lesser amounts of dopamine.

>>12706985
Phase seperating literature. Pappu and holhouse have some good stuff.

Pollack has some slightly crackpot water chemistry

Deep lore is gilbert ling