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/sci/ - Science & Math


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12052934 No.12052934 [Reply] [Original]

Sialic acids play an essential role in maintaining bacterial growth, survival, and virulence. According to the current study hypothesis, in a condition like bacterial vaginosis, bacterial population with sialidase activity mutually facilitates the persistence of bacterial species that do not have sialidase activity.
Mutually beneficial relationship between diverse bacterial populations in the vagina

Fusobacterium nucleatum is a Gram-negative bacterium predominantly found in the human mouth. This bacterium does not have endogenous sialidase activity and is known to colonize with bacterial population that has sialidase activity. As hypothesized by the researchers, F. nucleatum may utilize sialic acids as a nutritional source in the presence of exogenous sialidases produced by sialidase-positive bacteria.

Using both in vivo and in vitro experimental models, the researchers observed that F. nucleatum cannot utilize glycan-bound sialic acids because of the absence of sialidase activity. However, upon colonization with sialidase-producing vaginal bacteria, F. nucleatum can get nutritional benefits from sialic acids. Moreover, the researchers found that F. nucleatum maintains a mutually beneficial relationship with sialidase-producing bacteria by triggering the characteristics of vaginal dysbiosis, such as increased sialidase activity and enrichment of Gardnerella vaginalis. The maintenance of vaginal dysbiosis, in turn, facilitates the persistence of susceptible bacterial population in the vagina.


Journal reference:

Agarwal K. 2020. Glycan cross-feeding supports mutualism between Fusobacterium and the vaginal microbiota. PLOS Biology. https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000788


https://www.news-medical.net/news/20200826/Oral-sex-can-trigger-bacterial-vaginosis.aspx

>> No.12052936

Besides the synergistic relationship between microbial populations, antagonistic interactions do exist to maintain vaginal homeostasis. Lactobacilli (good bacteria) that are present in high amounts in women without bacterial vaginosis induce a lactic acid-enriched and low pH condition in the vagina, which in turn facilitates the removal of F. nucleatum.
The link between oral sex and vaginal dysbiosis

Because F. nucleatum is present predominantly in the mouth, it is generally considered that women acquire this bacterium in the vagina via oral sex. Moreover, oral sex contact is known to be a potential risk factor for bacterial vaginosis.

The current study findings indicate that vaginal exposure to F. nucleatum increases the growth of Gardnerella vaginalis, even if very low numbers of F. nucleatum are introduced. According to the researchers, oral sex can increase the chance of mouth-to-vaginal transmission of the bacterial population that can subsequently facilitate the maintenance of vaginal dysbiosis.
The current study significance

The current study provides valuable information about bacterial symbiosis through ‘metabolite cross-feeding’ that can actually facilitate the colonization of pathogenic bacteria in the vagina, as well as provide a suitable condition to maintain vaginal dysbiosis.

Moreover, the current study findings clarify why having bacterial vaginosis increases a woman’s susceptibility to vaginal colonization of pathogenic bacteria that are responsible for intrauterine infection and other health complications.

>> No.12052939

A new study published in the journal PLOS Biology has revealed diverse microbial populations can facilitate vaginal colonization of pathogens, which in turn can prolong the characteristics of bacterial vaginosis, a condition characterized by an imbalance of vaginal microbiome. The study findings also provide evidence linking oral sex with bacterial vaginosis.

What is bacterial vaginosis?

Bacterial vaginosis is a common condition of vaginal microbial imbalance (vaginal dysbiosis), affecting about 29% of women in the United States. In women with bacterial vaginosis, the number of beneficial bacteria reduces, and the colonization of pathogenic bacteria increases. Although the condition is mostly asymptomatic, it can put a woman at higher risk of developing sexually transmitted diseases and urinary infection. In pregnant women, bacterial vaginosis can increase the chance of preterm birth.

Although the exact etiology of increased pathogen colonization is not known, it is generally believed that a reduction in ‘good bacteria’ level may facilitate the entry and colonization of pathogens inside the vagina.
The current study hypothesis

In the current study, the researchers hypothesized that the presence of sialidase activity in the vaginal fluid of women with bacterial vaginosis is responsible for pathogen colonization and maintenance of vaginal dysbiosis.

In this context, previous studies have shown that in bacterial vaginosis, an abundant bacterial species (Gardnerella vaginalis) generate sialidases to induce the secretion of sialic acids from mucosal components and cell surface glycoproteins.

>> No.12052946

>>12052934
I've wondered about this in the other direction. Couldn't the oral biome change as well?

>> No.12052949

>>12052946
probably

>> No.12052959

>>12052934
So, rinse with mouthwash before going down on a girl?

>> No.12053008

>>12052934
https://www.barstoolsports.com/blog/2770652/cardi-b-breaks-down-the-reason-some-ladies-have-dap-dry-ass-pussy

>> No.12053231

>>12053008
Gross

>> No.12053278

>>12052934
sex is fucking awesome, rejuvinating, and energizing. it clears neurotoxins and floods the brain with a natural dose of oxytocin.

so fuck your gay science shit lmao

>> No.12053280

>>12052959
>>12053278

>> No.12053288
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12053288

>> No.12053299

wow OP thanks for your high IQ post. every noncel also knows that women worry about UTI’s after cunnilingus even moreso. so yes, anon above who said listerine before going down— yes, good etiquette

>> No.12053316

Can trigger all sorts of cancer too.

Oral is dangerous, the mouth is a sewer. Get angry all you want, but it's fact.

>> No.12053321

>>12053316
fuck thats hot. bring on the cancer

>> No.12053394

>>12053321
this thread is already cancer

>> No.12054293

bump

>> No.12056502

bump

>> No.12056688
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12056688

>>12053278
>rejuvinating, and energizing
Manwhore and roasties tell otherwise
Women who fuck around look older and unhealthy

>> No.12058224

bump

>> No.12058260
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12058260

It works in reverse too. The main cause of halitosis for men is performing oral sex on women. It is cucked behavior and was considered disgraceful for most of history as it places men in subservient position to women, thereby emasculating them. Most times cunninglingis is a cope for premature ejaculation.

>> No.12058267

yeah, [math]\color{lightblue}{\mathrm{vaginosis}}[/math], cool image you got there, OP, ahahahaha

>> No.12058282
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12058282

>>12053278
>sex is fucking awesome
You're deceived by the reward of pleasure which is just a base reward no similar than drugs. You aren't assessing it objectively
>rejuvinating and energizing.
False. For men its followed by apathy and lower motivation because their evolutionary purpose has been fulfilled and the body forces itself into slow mode by pumping it chock full of prolactin.
>it clears neurotoxins
False. If anything it creates the potential for even more neurotoxicity due to dopamine hence DOPAC metabolism
>and floods the brain with a natural dose of oxytocin.
Which disrupts homeostasis and makes you have peaks and dips in it contingent upon your frequency of sexual activity thereby making you have less when you actually need it for social interactions. This is one reason many people are socially anxious after copulation and masturbation and one reason it forces pair bonding and reliance on the mate.
>so fuck your gay science shit lmao
Says the one who reiterated pop-sci brainletism probably from a buzzfeed article.

>> No.12058285

>>12053278
Also, reading this again, this is just roastie cope for your dog tier behavior.

>> No.12058292

>>12056688
[citation needed]

>> No.12058299

>>12058260
Kant was a faggot

>> No.12058312
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12058312

>>12058299
He refuted faggots.

>> No.12058468

>>12052934
is there not potential for disease transfer from mouth to mouth too? Kissing? Everything is a potential hazard the main way to prevent this is to only have ONE partner for life and a hygienic partner

>> No.12058477

Fuck that, I won't stop licking my GFs pussy and ass.

I like to drink red wine and get pissed with my friends and eat lots of meat, sue me.

>> No.12058497

>>12058260
absolutely true
All the dudes who say you should get good at eating pussy are fat fucks with ed, premature ejaculators, and small dicked guys who are insecure

>> No.12058574
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12058574

>>12058477
>Fuck that, I won't stop licking my GFs pussy and ass
>I'll never admit it but I actually have premature ejaculation and am just projecting my cope with even further perversions like ass licking

>> No.12058719

>>12052934
Femoids carry another disease too, a parasite, i think it's called Giardia.
It doesn't affect women (real ones)

>> No.12060816

>>12058719
It affects men who commit oral "sex" on a woman.

>> No.12061213

>>12058260
How to cure?

>> No.12061330

>>12053008
Thats actual solid advice, most people have no idea about basic sex hygiene. Washing your dick before sex is mandatory especially if your are circumcised since that layer of skin for Natural Penises helps protect it from foreign bacteria.

Brushing your teeth and tongue a hour before oral for both partners.

https://health.clevelandclinic.org/throat-cancers-link-oral-sex-know/

>> No.12061433

>>12058292
You can cite your mom

>> No.12061460

>>12052934
If I ma add my own scientific observation, never smother her pussy in the syrup from a can of peaches, then eat her out like a starving man at Bottomless Pasa Day. Sure, it's fun at the time, and she'll come like you've never seen before.

The yeast infection from that much syrup will close the gates to Funland for at least a week afterwards.

>> No.12062178

bump

>> No.12062187

Lmao why are you all faggots spending so much time talking or having sex? like, just fap for 2 minutes if you're horny and be done with it lmao

>> No.12062419

>>12062187
This but unironically.

>> No.12063515

bump

>> No.12064560

bump

>> No.12064564
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12064564

>/u/maxwellhill thread

>> No.12064584

>>12052934
CHECKMATE DYKES

>> No.12064840

>>12058312
wow such facts and logic

>> No.12064842

bump

>> No.12067380

bump

>> No.12067431

What does this mean?

>> No.12067831

>>12058497
So what should guys do instead if they have ed, premature ejaculation, or small dicks?

>> No.12067851

>>12056688
>woman who has sex once a week with a different partner is an aged sickly roastie

>woman who has sex with her husband twice a day every day is a healthy specimen with a flawless tight pussy

really jogs the noggin

>> No.12067864

>>12067431
It means that licking a vagina might cause discharge, itching and pain.

>> No.12067870

>>12067851
Oh look at you ! Bringing logic and reason into someone's personal prejudices.

>> No.12067873

>>12067831
get cucked. it’s going to happen either way. at least this way you aren’t becoming diseased

>> No.12068973

bump

>> No.12069031

>>12067851
>woman who has sex once a week with a different partner is an aged sickly roastie
Correct.
>woman who has sex with her husband twice a day every day is a healthy specimen
Correct.
>with a flawless tight pussy
Incorrect.

>> No.12069051

>>12053316
Don't even get me started on anal.

>> No.12069184

>>12058260
Jokes on you m8 I've got shitbreath and haven't been near a pussy since I plopped out of one

>> No.12070054

bump

>> No.12071419

bump

>> No.12072966

>>12058260
>The main cause of halitosis for men is performing oral sex on women.
Cite?

>> No.12072989

>>12052934
i hope this publication wont get censored because of it not being PC enough

>> No.12074171 [DELETED] 

bump for femanon health

>> No.12074181
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12074181

>>12074171
[math]\mathrm{I~drink~for~\mathbb{\color{#DD40AA}{your}}~health,~sweety.}[/math]

>> No.12074203

>>12067851
Yes, that is correct, the woman with a single partner will also learn to tight her vagina to adapt it to his husband's dick.

>> No.12075630

bump

>> No.12075632

>>12075630
why are you bumping this? what is there to discuss? let the thread die jesus

>> No.12075665

Bump for based cunt science

>> No.12077092

bump

>> No.12077219
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12077219

>>12058282
Nofap forever