/sci/ - Science & Math

>>11275851
Because you aren't trying hard enough to fix it. Or maybe you're not smart enough to fix it, so you deserve to be bald. But honestly, you keep making this thread which is pretty annoying but the satisfaction of knowing some balding piece of shit sitting in a dark room is making these threads completely drowns out the anger of seeing them constantly. It's like getting angry at an autistic manchild for being obnoxious, but you realise getting angry is the wrong emotion and laughing at them is much more appropriate

>>11275875
Listen you fucking spineless American piece of incel garbage. I haven’t made any other thread about this you faggot Jew. Answer the question or kys

>>11275888
I answered the question faggot. You're not trying hard enough to fix your balding

>>11275851
Learn to live with it, it's entirely cosmetic

>>11275895
How to fix baldness

>>11275901
>Learn to live with it
>it's entirely cosmetic

and if you don't learn, it can causes emotional problems which lead to increased chance of heart disease. Which means it's not entirely cosmetic.

>>11275919
You choose to have that emotional distress. people live fine going bald, and you can too if you come to terms with it

>>11275851
It is, eat onions and you won't go bald, onions prevents excess testosterone AKA toxic masculinity.
Hitler wasn't bald, Churchill was bald.

>>11275851
Baldy+wig=syndrome cured!

>>11275919
imagine getting a heart attack because you're bald

>>11275851
There are prescriptions you can get for male pattern baldness that decrease testosterone levels to combat balding. But you can only do that so much before you really screw up someone's hormones.

>>11275851
propecia, if youre such an insecure faggot

>>11275851
Buy a hat

If you're balding just shave it off completely like Jeff Bezos.

There already practically cures for baldness. The fact you haven't found them just shows how lazy and undeserving you are.

>>11276305
Propecia? Hair transplant? Needling? Systems? What is it?

>>11276310
Hair Transplants with 5α-Reductase inhibitors, PRP with Stem cell therapy, and multiple types of peptides treatment.

>>11275851
it is though, its called finasteride

>>11275851
red light and aspirin

>>11276316
unironically is it worth it?
I mean losing hair is not the end of the world,

>>11275851
There are multiple levels to counteract hair loss.
At the very basic level, you have to make sure you're getting enough vitamins, antioxidants and minerals in the first place to nurture the hair follicles. Vitamin C, Vitamin D3 + K2mk7, Biotin, OPC is all beneficial for hair growth.
Then there is over-the-counter medication such as minoxidil and the new formula redensyl (Panthrix), which increase blood flow and nutrient supply. You can combine these with derma rolling for increased uptake into the dermis.
Next, finasteride and other DHT-blockers. These stop the highly reactive androgen from being converted out of testosterone. Since it messes with your hormonal balance, this is more dangerous and can lead to more undesired effects.

>>11276316
What this anon said can be done once everything else fails.
Hair transplants especially depend on the individual. You can only do as many grafts as your donor area allows, sometimes needing more than one if further hair loss occurs. Worst case you'll be ending up with wads of transplanted hair, while everything else continues to fall out.

>>11275851
Needling, rogaine and supplements. You have to keep up on it though for at least a year. Hair transplants if you got the money.

Propecia can really fuck you up since it just turns off the AR receptors DHT> testosterone it will chemically castrate you. The non company paid studies showed around 25% of people have problems right off the bat. The rest is a matter of when after a year or more of continuing use. Don't use propecia.

>>11275895
You're fucking retarded

>only cosmetic

Akshuly, it goes hand in hand with various hormonal problems, libido and overall man's health.
A cure is probably not possible, but a treatment would be super.
The cosmetic aspect is also very important.
I happened to meet my wife just before the Tinder boom, but from what it seems, if I had to find a mate in the current hyper-sexualized market, I would kill myself.
I'm balding, and I think bald men are pathetic. If my daughter would marry a bald man I would be disappointed.
I think we know bald men are shitty on a psychobiological level.

>>11276876
And this comes fro an Israeli, BTW.
Jews are predisposed to balding, so being bald in your 30's is not uncommon here. I have been to places in Europe where I was literally the only balding person on a busy street. I don't want to imagine how being a bald single male must be like there.

>>11275851
Castration is a very effective cure.
A bit drastic I may say, but if you really care so much it works.

>>11276885
>been to places in Europe where I was literally the only balding person on a busy street
Must've been an unlucky day, many Euros go bald too. Especially southern ones. The likelihood of balding seems to coincide with general hairiness and comes down to the amount of androgenic receptors in the hair follicles, fewer receptors in the follicle means it's more affected by DHT (which leads to hair loss on the scalp and increased hair growth elsewhere).
If you have a strong beard, you can just shave your head. If you lack facial hair and you're balding, you might as well kys.

>>11275851
Probably because it is not a life threatening condition and is a result of multiple factors. This is also likely why there has been relatively little genetic research done on male pattern baldness in general; larger institutions and research grants are mostly spent on curing more immediate life ending threats such as cancer. I've lucked out genetically and still have a full head of hair, but can't grow a beard to save my life so I wouldn't mind seeing more studies. Unless some balding billionaire (looking at you Bezos) wants to shell out millions of dollars in funding the research though, I wouldn't expect anything resembling a "cure" for decades outside of maybe an accidental discovery of a slightly stronger Rogaine + needling combo.

I think he knows

I dunno, OP, but I do know that when a simple cure is found that completely eliminates and/or reverses it, the entity that creates said cure stand to make trillions of dollars.

>>11276076
Yeah then the main problem isn't your baldness.

So here's a crazy idea that I think needs experimentation.

Needling is a proven effective way of reversing or preventing hair loss. How does it work? You damage the skin, which triggers a healing response in the skin, and the hair follicles accidentally get healed. Which got me thinking isn't there a better way to trigger a healing response other than jabbing yourself with needles?

And then I remembered something from the hypnosis thread the other day. I can't find the thread so I don't have all the details, but the gist was they blindfolded someone, somehow convinced them they were going to touch a red hot coal to their skin, when it fact it was a cold coal. This triggered a nocebo/placebo effect causing their skin to react with burn blisters as if it had been burned. THEY TRIGGERED A HEALING RESPONSE!!! Why can't we use nocebo/placebo or hypnosis to trigger the same type of healing response in the scalp, but in a way that heals hair follicles instead of causing burn blisters.

tl;dr in theory, you should be able to cure baldness with simple hypnosis/placebos

>>11275851
Baldness is based.

>>11275851
because rna mods lead to immortal beings and fuck you.

>>11276076
It's not because, there's just a correlation of having MPB and having heart failure.

>>11277946
video or it didn't happen

>>11276977
He just got a run of the mill hair transplant.

>>11275851
The cure is called sexual selection.

>>11278826
too much enviro influence, sex sel not eff

>>11275851
Because the actual scientists (physicists) haven't gotten around to it yet.

>>11278826
except boldness uuuusually begins to set in after sexual selection has done it's job.

I took a picture of my head in a Greg's security camera the other day. It shocked me. Am I beyond saving?

>>11275851
Because it would require doing serious science on human biology, and ethics boards forbid that.

Ethics boards and their consequences have been a disaster for the human race.

>>11276301
This

>>11275851
Because it isn't an important issue. Shave your head like everybody else.

>>11279402
This

>>11275851
It is though. Topical finasteride or RU58841 will stop balding in 90+% of men. It's easier to prescribe and use pills though, even if they make you dick soft, so they're popular. And RU58841 is still niche and probably isn't profitable, so it will never see widespread use.

>>11275851
It is (for like 85% of people). Take finasteride.

>>11279529
>even if they make you dick soft
This only happens, temporarily, in like 1% of men. And there is not a single study done to date that shows permanent side effects. Not one. All of them show the contrary; that the side effects go away after roughly half a decade (in the 1% of people that actually ever get them)

>>11276392
PRP is a ripoff, but it works. It should cost like $100. All they do is draw blood, put it in a centrifuge, and inject the PRP into the scalp. Literally, that's it. But it's mostly transplant clinics that do it, and the gyp the price up to thousands of dollars for a single treatment.

It won't stop balding, but you can get short-term thickening of hairs if you've already had some thinning. Use a topical anti-androgen to prevent further degradation and you're good to go more or less indefinitely.

>>11279534
I'm not talking about permanent side effects. I'm talking about losing you morning wood and having watery cum while you're on the pill, even if you can perform otherwise.

I don't see any reason not to use a topical instead now since the risk of any side effects whatsoever are about 0%, and they seem to be even more effective.

>>11279321
>taking pictures of yourself in fucking greggs
>posting those pictures online
Yes, you are, unless you realise how bizarre this behaviour is and start changing your ways. Don't be a weirdo mate.

>>11279534
>1%
no.
>And there is not a single study done to date that shows permanent side effects.
https://ec.bioscientifica.com/view/journals/ec/8/8/EC-19-0199.xml
https://www.sciencedirect.com/science/article/abs/pii/S0960076017301024
https://www.sciencedirect.com/science/article/abs/pii/S0306453018305067
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479083/
etc

>>11275926
This is 100% shit. Baldness allegedly id a sign of low testosterone but more so high muscle mass. Im 1.81 meters tall and tipped to fuck never even took protein suplements and my hair is long like a viking warrior. Are you gonna admit uou fucked up or are you gonna claim im bullshiting

>>11279553
Those are side effects and none of them have been shown to be permanent. On the contrary.

>>11279635
Did you read any of those studies anon? Like even one of them? Or my comment? Let's go through them together...

Again, here's my claim:
>Only happens temporarily
>In *like* 1% of men
>men
>not a single study shows permanent side effects
>side effects go away after roughly half a decade

>https://ec.bioscientifica.com/view/journals/ec/8/8/EC-19-0199.xml
Neat. Nothing here contradicts anything I claimed.

>https://www.sciencedirect.com/science/article/abs/pii/S0960076017301024
Wow, "persistent side effects MAY occur"? You really proved me wrong anon!

>https://www.sciencedirect.com/science/article/abs/pii/S0306453018305067
PFS again. One month after withdrawal. Mice studies. Boring. Irrelevant.

>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479083/
>Mice study
Anon you aren't this dumb are you?

>etc
Oh, there's more? I'd love to see them and I hope they're better than the ones you just linked here. Because all you've done is proven my point.

>>11279739
>Baldness allegedly id a sign of low testosterone
Anon... please... just take 5 minutes to do research. Just 5. That's it.
>It is true that balding is dependent on testosterone. Back in 1960 a Yale doctor called James B. Hamilton studied twenty-one boys who were undergoing castration. Shockingly this was sometimes done to boys diagnosed with behavioural or mental problems. He followed them up, some of them for as long as 18 years, and found that they showed no signs of developing male pattern baldness as they aged. On the other hand, men of the same age who were still intact, and therefore producing testosterone, already had receding hairlines.
Baldness is caused by testosterone. If you quite literally can't go bald.

>>11279635
>To date, there is no evidence-based data substantiating the link between finasteride and persistent sexual side effects in the numerous double blinded, placebo controlled studies using finasteride 1 mg for hairloss.

>The persistence of sexual side effects appears to be a rare event, and it has yet to be determined whether these recent reports represent a true causal relationship, or if they are simply coincidental and related to other factors such as the high incidence of sexual dysfunction in the general population, and/or the placebo effect. Also, little data is available concerning the medical and psychological work-up of these patients to exclude other potential causative factors.

>Currently, there is no direct link between 5-alpha reductase inhibitor use and depression; however, several small studies have led to depression being listed as a side effect on the medication packaging.
>On average, the sexual dysfunction occurred 1.8 years after starting finasteride 1mg daily and lasted 5.4 months after stopping the medication.45 Overall, persistent sexual dysfunction associated with finasteride use is somewhat controversial46 with conflicting results between studies.

>We found no evidence of androgen deficiency, decreased peripheral androgen action, or persistent peripheral inhibition of SRD5A in men with persistent sexual symptoms after finasteride use.

>Many of the individuals were recruited from an Internet website for individuals with persistent sexual side effects after using finasteride. It is probable that these individuals are more seriously affected by sexuality or have more severe sexual dysfunction and, thus, are more likely to participate in and seek out the study. In addition, these findings may not pertain to individuals with less severe sexual dysfunction. Moreover, as referenced above, in the 07 study by Mond et al,14 a significant placebo effect was detected when patients were informed in advance about possible sexual dysfunction.

>>11279822
>Baldness is caused by testosterone. If you quite literally can't go bald.
Baldness is caused by DHT, a metabolite of testosterone proper. Whether you go bald or not depends on how resistant your scalp hair follicles are to DHT, it's mainly genetic.
Producing testosterone is a prerequisite for MPB, but being bald doesn't mean you have high T and having full hair doesn't mean low T.

>>11276076
mfw

i can grow a really thick beard.
Is it over for me bros??
I would sacrifice this power to preserve my hair any day of the week.

>>11275851
Polygonum multiflorum and ashwagandha. Make a tea, treat your scalp with it. If you're balding to begin with it's because your blood flow and antioxidant status is poor. Use NAC and vitamin C.

>>11279817
I didn't say those effects were permanent. I said they are common *while on the pill*. And considering you have to take the pills *for the rest of your life*, that means slight noodle dick and watery cum *for the rest of your life*, unless you stop taking the pills.

I agree that the only horror stories of permanent impotence and all that are overblown, and those men probably already had other serious hormonal issues or other conditions to begin with.

>>11280926
>>11279817
So there's basically no risk to trying the pills, but my original point stands: topicals are more effective, and have zero size effects *during use*, and RU58841 doesn't require a prescription and the repeated doctor's visits every time you want a refill.

>>11275851
>he wants to cure baldness instead of curing aging

>>11275922
>people choose to have emotions
based retard

>>11280951
hes not making daily sacrifices to roko

feels bad when you gonna spend eternity in real life hell

>>11276909
only before puberty

>>11275851
It's a proven fact that SCIENTISTS believe people who BALD have less IQ than there full haired counterparts due to in the BALDING process, less BLOOD is sent to the scalp meaning less oxygen for the BRAIN.

bald dudes have been breeding for thousands of years. I don't think it's your hair that makes you unable to have a satisfying relationship bro.

baldness isn´t dangerous

>>11276128
lol

>>11279530
But doesn't it have horrible side effects? What is /sci/'s take on fin?

Because anyone who cares about going bald is too pathetic to get laid anyway

>>11275851
>considered a genius
>still couldn't solve male pattern baldness

>>11279817
>Did you read any of those studies anon? Like even one of them? Or my comment? Let's go through them together...
yes

>Only happens temporarily
>In *like* 1% of men
impressive that you are able to calculate an unknown with such certainty. it is not known what fps even is, what mechanisms are involved or how many variations there are; methylation and neurosteroid deficiencies in patients that have been *off* finasteride for years have only very recently been discovered, there is zero data post these discoveries to make the claims that you do. the 1% figure that you parrot is based off the listed *previously known* and expected side effects and even that is disputable.

>>not a single study shows permanent side effects
>https://ec.bioscientifica.com/view/journals/ec/8/8/EC-19-0199.xml
methylation of the 5ar2 gene in *post*-finasteride patients. I have yet to see any evidence that artificially methylated genes return back to normal under any amount of time, please link me if you have proof otherwise
>https://www.sciencedirect.com/science/article/abs/pii/S0960076017301024
neurosteroid deficiencies *still* occuring on the 5ar pathway despite cessation of finasteride for years in patients

>side effects go away after roughly half a decade
again, based off different side effects and outdated data, we are not talking exclusively about the side effects listed on the box

>>11279844
>2012 paper
that paper was correct, at the time we didn't have any data proving methylation and continued enyzme disruption but now we do. also to be clear, research into this is still highly underfunded and relies heavily on charitable donations, the whole picture is still very unclear.

>>11285186
cont;
here's a paper from a few weeks ago calling for further research into the issue;
https://www.sciencedirect.com/science/article/pii/S235228951930061X

>This condition, named as PFS, seems to be present in male patients, with an incidence on the total population that is still unclear.
unclear =/= not 1%

>However, also in this case, concerns about PFS existence have been raised. Overall, these data indicate the urgent need to high quality clinical trials, with long-term follow up, specifically addressing sexual function and mood disorders. In addition, it is imperative to study in detail the molecular mechanisms that cause this condition, trying to identify a possible genetic predisposition, in order to limit the burden of PFS. Finally, therapeutic strategies, like for instance neuroactive steroid treatment, able to relief or to cure this condition are also urgently needed.

How well does topical finasteride perform in comparison to its oral counterpart?

>>11285186
>“If abnormal SRD5A2 promoter methylation is established prenatally, these subjects
could be predisposed to develop the PFS and alteration of neuroactive steroid levels in the brain. In this case, treatment by finasteride might precipitate a dormant depressive
phenotype linked to such specific epigenetic pattern, resulting in the clinical picture
described previously.”

no causality established. ashton kutcher was on dutasteride for 10 years and seems fine, and that knocks out type 1 ar as well. plus the south american tribes with natural ar deficiency are healthy and normal outside of the effects from the absence of prenatal DHT exposure, not a problem for adult males taking fin

>>11283109
Cope. Baldness is linked to high creativity and bdnf production. Show me the link about IQ.

>>11275851
Having a full head of hair is overrated

If you take female hormones and testosterone blockers and add in some finasteride too your hair regrows like crazy

bonus points for throwing in minoxidil and weekly microneedling on top of that.

>>11285891
Is it possible to isolate estrogen to only one part of the body?

>>11278101
There's no need to go straight for the conspiracy theories.
It's much more easily explained by Musk having been replaced by a reptilian doppleganger.

>>11275851
The problem is not being bald, baldness is just a haircut, the real problem is being ugly/fat

>>11286299
cope

>>11275851

Cure for baldness already exists.

>>11275851

Because there already is a cure and it is called hair transplantation. Seriously all you whiny fucking faggots keep going on about how there is not a cure for baldness when it is RIGHT THERE in front of you. That's like some lady asking why there isn't a pill she can take to make her A cup tits a DD. Because there is surgery. In the next few years hair cloning will probably be a thing (albeit expensive) so there won't be a limit to how many hair you can have transplanted (right now the limitation is the donor area in the back of the scalp). Just stop dwelling on it you fuck. I'm balding too and I've had enough of these asshole threads.

>>11288187
All you people talking about hair transplantation have never seen it up close. It's disgusting

>>11275901

>>11287791
Top kek

>>11275851
>skin health
>circulation
>nutrition
>hormones

All of these contribute to baldness, but only hormonal issues are regularly treated.

>>11275901
Im not OP but thats no fun, i'd like it people documented their different attempts as it all brings us closer to understanding this phenomenon. Personally i believe a mix of Peppermint oil and Rosemary oil with some sort of strong carrier agent could do the trick.

>>11286292
He's tricking you into becoming a trap

>>11275851
Nobody wants to cure it, so why bother?

The medical industry makes more money from helping you manage it, a straight cure would be a cheap ass pill (or start off expensive and people would bitch and moan and they would be forced to lower the price).

Medical breakthroughs only happen if its profitable, if not research doesn't get funded. This idea that mankind is working to fix this shit is laughable, that's not how it works anymore.

Same applies to the common cold, if they wiped out that virus they would lose trillions of dollars.

Finasteride fucked me up. I was unlucky to get almost all of the side effects almost immediately. Severe depression, watery sperm, loss of sensation when cooming, even gastrointestinal issues. As a minor upside, it made my facial hair grow very slowly which was kind of neat. It also made my hair and skin less oily.
Anyway, I decided that ruining my body over mpb wasn't worth it and stopped taking it. Luckily the sides eventually went away. The depression was the worst, I literally had suicidal thoughts every day during that time.
My case isn't typical but still. PFS is real and even if you get no sides you'll be doing permanent changes to your body by taking it long term.

If you seriously consider the hormonal route, just go full tranny.

>>11286292
It's not possible. Topical estrogen will give you more or less the same effects as pills or injections.
You could try "microdosing" it but either the dose will be too low to do anything for your hair or it will be high enough to upset your hormonal balance and get side-effects like infertility, gynecomastia and turning into an anime girl.

>>11275851
It's not covered by insurance

>>11275901
>it's entirely cosmetic
Baldies have higher chance of diabeetus, heart disease and prostate cancer.

>>11276909
It stops balding but doesn't give you back your old shit

>>11277946
>How does it work? You damage the skin, which triggers a healing response in the skin
More or less. Due to some genetic fuckup too much cxxc5 inhibits the wnt beta catenin pathway which then inhibits hair growth.
Wounding activates wnt. The researcher's name is choi. Look it up. I think he's on to something.
https://www.sciencedirect.com/science/article/pii/S0022202X17315555

>>11288187
Imagine being this much of a brainlet.
Transplanted hair does fall out too unless you take fin which brings us to the debate above.
It's also not suited for diffuse balding and most things below nw3

>>11290883
>helping you manage it,
Ah, come on. Fin and minox is ass cheap.
>if its profitable, if not research doesn't get funded
That's the reason. Research is expensive and hair loss is not covered by insurance.

could someoen explain the science behind the level of insecurity that would lead someone to take a pill that alters their hormone levels for exclusively superficial reasons like baldness, it seems like we're born with a concern for superficiality I can understand if it's something like deformities or even lack of muscle but from a survival standpoint baldness wouldn't effect anything but yet insecurity about being bald seems to be something people are born with

I don't understand people taking substances radically altering their chemical balance, like women taking the pill or men taking shifty anti-baldness drugs.
There's the regular retards taking illegal and legal drugs.
There's the steroid and adderall users.

I think that all these drugs should be legal and free for all, but you have to go get yourself permanently sterilising to access them.
It would do wonders on the genepool.

>>11291578
>>11291269
People always say things like this until they go bald themselfves.

>>11291632
I am, and it is not affecting my mental state.

I don't think being bald is so bad
you have a nice shiny head
you look tougher
Look at Vin diesel
Look at Agent 47

all you have to do is get /fit/ and you look great

>>11292436
unless your face or head shape is wrong

I've been on fin/min for almost 3 years now and I've had great results until I've developed seborrheic dermatitis (alcohol in the minox fucked my skin up) which in turn caused massive shedding so I've switched to oral minox.
Now the inflammation has pretty much been treated but the hairfall persists.
Any of you fuckers know if this could be due to the meds stopping working or some shit?
My derm says it's the inflammation and the switch to oral minox but I'm fucking scared, don't wanna start losing my hair again bros...

not an illness