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10994207 No.10994207 [Reply] [Original]

this thread is for the discussion of psychiatric drugs, neurological conditions, and neurology in general.

I have a neurodegenerative disease and I have found the research articles about the treatment of apathy, depression, and aggression behavior very interesting, so I wanted to start a thread for general neurology and you can talk about IQ if you want to as well.

I am reading about the use of stimulants(usually methylphenidate) to improve apathy, depression and focus in neurological disorders, and about the use of propranolol, and Carbamazepine for irritation and aggression.

>> No.10994239

CIA niggers use psychiatric meds to domesticate the population

>> No.10994253

>>10994207
>depression
>>>/x/

>> No.10994261

best medicine for disease is natural selection
after that its a healthy lifestyle

but seriously, how close are we to real regenerative medicine? it was always pushed in highschool biology that stem cells would change everything

>> No.10994262

>>10994253
Depression or apathy induced by brain damage is a scientific topic, it responds to medications like Ritalin or adderral

>> No.10994266

>>10994261
It isn’t even being considered from what I read using stem cells for brain injury is considered almost pseudoscience at this point.

Medications are shown to be effective for symptoms

>> No.10994369

manic depressive here

do you guys think taking valerian root will help me with my mental fog

>> No.10994376

>>10994266
are you sure about the stem cell thing?

http://www.crm.ed.ac.uk/research/group/stem-cells-and-regenerative-neurology

https://www.ncbi.nlm.nih.gov/m/pubmed/26748435/

I'll be honest I don't know much about biology or medicine. I should probably read the BRS series

>> No.10995675

>>10994369
>Using a GABA agonists for MD
Oh boy, you get to feel manically depressed while physically relaxed. Yay!

>> No.10995758

I have a delusional psychosis that I've only ever told one person about. (I'm 33). You could dismiss me offhand because of self diagnosis.

I didn't even realize it for what it was until just a few years ago. I've had depression for most of my life and it started getting particularly bad after the birth of my son. I went to see a doctor about it and was prescribed welbutrin. After the first night of taking it I felt pretty normal, the second day my gf went to hang out with a friend of hers while I watched the kid since I was doing alright. She calls me a few hours later and I smell rotten meat coming from the reciever of the phone and I just knew it had to be because there were demons around. When my gf got home I warned her that her friends were not to be trusted because I feared they wanted to take the baby away from us for some nefarious purpose.

I was having a full blown psychotic episode and was completely unaware because all those things seemed reasonable at the time.

I stopped taking the welbutrin a few days later and the delusional episode stopped overnight. And you can bet I'll never take any other type of anti-depressant regardless of its mode of action

So to my larger point. This episode elucidated something for me. I have always been delusional, but I wasn't aware of it until then. But the sad thing is that my primary delusion is something that I can't shake like the medication induced episode. It comes and goes over the years but basically the delusion is that I'm this dream wizard/warrior guy that is entrusted with this magical weapon and its my duty to fight these miasmic shadow creatures from another dimension, and I have allies somewhere out there in the real world but they don't know who they are and we only meet when we dream. And apparently this entire universe is just a node in a larger nexus that we can access through dream and death of course.


Fun stuff, except it's not fucking funny guys. Our brains are truly strange

>> No.10995881

>>10995758
Embtace it for what it is. Write a book with you and your dreamfriends as the characters. It might even be good.

>> No.10995893

>>10995758
Sorry for you. Do you get treatment tho? Afaik, psychoses work similar to depressive episodes in that they can be caused by too much stressors (i.e. birth of a child) at the same time. Therapy can help to manage those.

>> No.10996458

>>10995758
So what's the likelihood that antidepressants will cause the average person hallucinations or delusions cause I'm spooked now

>> No.10996555
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10996555

Op here I have been aware that something is off about my brain for the past 5 years. I have been losing my memory and my executive functioning.

In the past month I have reached the point that I have lost interest in all my favorite hobbies....and I am beginning to lose interest in other people and having normal conversations. I have been aware that I am becoming apathetic and detached.

I spend all day mostly pacing around the house doing nothing at all because I cannot focus on hobbies I enjoyed as a child like video games, books or reading on the internet.

These are all symptoms of early Dementia, and my neurologist told me I most likely have an autoimmune neurological disease that is non Mendelian and that genetic testing is unlikely to find anything.multiple neurologists have said the same thing.

>> No.10996566

>>10996555
Stimulants don't help at all?

>> No.10996577

>>10996566
I haven’t tried them yet because of my mysterious heart rate problems, I monitor my heart rate every day with an Apple Watch and it remains at 90-120 most of the time.

I have been developing apathy and stimulants are the most effective treatment available. I should test it and see what happens

>> No.10996607

>>10996555
>>10996577
Damn son.


I have also heard that psilocybin can be used to treat such issues as well

>> No.10996628
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10996628

>>10996607
Is it just some coincidence that my corpus callosum was also extremely enlarged the average corpus callosum is around 7cm^2 in cross section, but when I measured my MRI I found it was 10cm^2 in cross section, I sent these findings to a research neurologist and the brain bank the neurologist said it was abnormal but he had no explanation for it and the brain bank wants me to fill out the donation form so it can be analyzed after I die.

>> No.10996674

>>10996628
That's interesting but I can't really answer that one for you satisfactorilly, especially if neurologists want to study it themselves. Perhaps it's due to some sort of inflammatory disease, and it's putting pressure on the reward center of the brain (which is nearby) decreasing its function

>> No.10996700

Either way I'd take the psilocybin suggestion seriously

>> No.10996723

>>10996555
Have you looked into diets to help alleviate auto-immune disorders?

>> No.10997038

>>10996723
I’m not even diagnosed they just found a very high Ana in my blood it has been the maximum value for years now...

>> No.10997058

>>10994262
The “off label” indication of adderall/Ritalin/modafinil for “treatment resistant depression” is really interesting. Makes you think: if you give someone a cognitive boost, they are no longer sad.

>> No.10997237

>>10997058
Depression != sadness, not usually

Depression is as it sounds, a feeling of weight. Sadness is down there sure, but there are feelings below even that. Sometimes sadness is preferable to that other shit which most people can merely define as "feeling nothing".

>> No.10997240

>>10995758
Goddamn son. That sounds cool and terrifying at the same time

>> No.10997261

>>10997237
Feel sad for long enough = depressed. Sadness is situational but if you do nothing to remove the sad context you will become depressed.!

>> No.10997273

Eventually you go numb because the sensory aspect of the mind is like “what even is the point senpai???” So there is an important need to react passionately/strongly if you’re being made to feel sad by someone/someevent. Once the depression sets in there’s literal nerve death and you will probably never ever recover. Being an “asshole” who refuses to let others make him sad is preferable to being a “nice” doormat who permanently reduces his fitness in order to go with the flow.

>> No.10997279

Treatment of depression is “management” treatment because once you’re fucked it is not possible to unfuck you. The treatment aims to allow you the semblance of a normal life and positive contribution to regular society.

>> No.10997284

Good news is that you aren’t the first person that this is happened to and a large part of our culture is built on the cope of depressed broken people. I suppose you can all huddle in your pathetic solidarity if you’d like.

>> No.10997313

>>10995758
>And you can bet I'll never take any other type of anti-depressant regardless of its mode of action
You don’t have to be such an alarmist. Bupropions (like Wellbutrin) are known to occasionally induce psychosis and other strange perceptual effects due to changes in dopamine generation. It only effects a small amount of people and obviously isn’t permanent or anything to be overly worried about. You should have just told your psychiatrist and he would’ve switched you to an antidepressant that works differently.

I understand the desire to not take any antidepressants, but to do so out of a misguided fear due to a known side effect is preposterous. There are many articles on psychosis and bupropion and your psychiatrist should’ve warned you in advance.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738405/

https://www.jabfm.org/content/21/3/244

https://www.omicsonline.org/open-access/bupropioninduced-psychotic-mania-risk-factor-clinical-course-and-dosage-2161-0495-1000269.php?aid=62878

>> No.10997472

>>10997313
Mainly what I worry abouy is getting suicidal. That's a known side effect of several anti-depressants. The psychotic was absolutely terrifying though.

>> No.10997481

Just saw neurologist she recommended neuropsychological testing, exome sequencing to check for any mutation causing neurodegenerative symptoms.

Disease may non mendelian

>> No.10997654

>>10997472
Can you stop worrying? Go climb a mountain or some shit. That will cure your ass of “motivation” when it’s 7pm and you need to make base camp or freeze to death.

>> No.10997678

>>10994261
Stem cells are cool but they're not THAT cool

Expecially in Brains. The neurons in your brain are the longest living cells in the body. You're actually born with almost all of them, and they die off from there.

They modify themselves over the course of your life (which makes sense because you're not the same person you are as a baby). So regenerating them with stem cells, while not even reliably possible, would not be ideal.

In parts of the brain where general function cells are used, and maybe glia, I could see a use for them. But neuron replacement, It's not looking super promising any time soon.

>> No.10997695

>>10997654
>motivation
Did you even read the guy's story? He has a legit psychosis and a medication meant to help with his depression brought on a psychotic episode. How do you think your little pep talk is going help? Have your never been actually terrified by something? You want to get as far away from it as you can.

>> No.10997698

>>10997678
I take your point but neurogenesis is a real phenomenon

>> No.10997739

>>10997695
They all have a story like this. All of these psychos. Once you hear one you’ve heard them all.

>> No.10997910

>>10994262
>>10997058
Amphetamine seriously fucks with your serotonin receptors - not just dopamine. It treating chronic sadness lines up with what we know; unfortunately, we don't know a whole lot.

>> No.10997916

fuck all of that mentally ill shit, Just breathe in air and sleep well.

>> No.10997940

>>10995758
I also had a psychotic episode shortly after starting an antidepressant (sertraline). In that state, I could hardly describe my thoughts - let alone write out a coherent post like yours. I was in denial for a bit when the lamotrigine took effect, but after that I quickly realized just how strange my behavior had been. Truly delusional people tend not to even have the insight necessary to separate belief and reality itself. Are you sure you aren't schizoid, or are maybe dealing with maladaptive daydreaming disorder?

>>10996458
Fairly high if you have a history of psychotic illness in your family.

>> No.10998023

To the guy talking about the dream world. What up team!

>> No.10998057

>>10997940
There are reports of psychosis in modafinil use too, and in any cognitive enhancers (let us consider SSRIs cognitive enhancers) there is this risk. It begs some interpretation. And it is unusual in its progression too. Re modafinil, one mother who took it for shift work disorder developed psychosis with constant repetitive thoughts/“realizations” that she has been a horrible parent to her children. Is this really psychosis? Or has modafinil brought some uncomfortable truths to the surface? The latter is more likely. Modafinil speeds up thought... people report reaching the correct answer faster much faster than at baseline, and the attentive matter for thought whatever it may be (your children, your work) is what your thought assails.

>> No.10998061

SSRIs literally upregulate serotonin in your brain, and serotonin is associated with the feeling of everlasting fully satisfied happiness, and also of intuitive emotional understanding. If you’re getting psychotic thanks to increased seotonin in your Brian, you’re probably being overwhelmed by the feeling of extension- of feeling/emotion/identity which is ordinarily an experience that people who exert themselves in nature, climb mountains, understand great works of literature, and love deeply passionately experience. Now you’re experiencing this without context so it appears “scary”, that is to say, unusual and intense.

>> No.10998068

>>10998057
Well, in my case it was actually pretty straightforward. My grandma had psychotic-type bipolar disorder, and I was warned that SSRIs could trigger mania specifically. I'm also not sure how it works, but thinking the FBI/CIA wanted to talk to me, that I was somehow secretly related to royalty, that everyone around had been talking about me recently and were making coordinated movements in response to my actions... that was full-blown, textbook mania; there's no doubt.

>> No.10998076

>>10998068
These are all classic paranoid fantasies. You find three psychotic persons and you’ll find two of them saying these exact things. It is different if you have direct family history, in which case you should live a really chill life in general and learn really good stress relief methods.

>> No.10998087

>>10998068
>but thinking the FBI/CIA wanted to talk to me
Because you are so smart and know so many things? It can be a feeing of your potential run amuck.
>somehow secretly related to royalty
So you’d consider yourself special and an elite?

>that everyone around had been talking about me recently
Very typical as well, but indicative of your feeling of being important and the “causal agent” of the world and people around you?

People report these kinds of experiences in fringe spiritual practice too (maybe the same thing as psychosis) and obviously in drug use this can occur (“induced psychosis” is what the 1950s psychiatrists called it).

>> No.10998104

>>10998087
>It can be a feeing of your potential run amuck.
It's what comes with mania, regardless of your background. I thought I was a genius, of course. Every psychotically manic person thinks that they're incredibly intelligent, strong, or both.

>> No.10998110 [DELETED] 

>>10998104
Are you successful in your life/career/school?

>> No.10998140

>>10998110
>Are you successful in your life
Absolutely not, but I’ve got other problems and was more or less doomed from the start. The psychosis simply toppled the house of cards that was my psychological well-being, so to speak.

>> No.10998142

>>10998140
Did you ever do well in school? In tests?

>> No.10998172

>>10998023
Hey senpai, got a nickname or whatever they call it on the other side?

Hopefully you're not fucking with me.

>> No.10998227

>>10998142
Sort of. I want to say I was brilliant yet lazy, but honestly it was more like clever yet incapable. My grades did not reflect my ability, nor my desire to succeed. I might as well have been a dummy.

>> No.10998814

>>10994239
Why use medication when we have media?

>> No.10999822

the neurogeneticist said that it is a strange symptom that I have self awareness of my cognitive decline, like imagine someone with dementia being self aware that they have dementia.

she said that I need to take IQ testing a second time to see how much my IQ has dropped, I made it clear that I don't expect to do as well as last time I got into MENSA last time I tested my IQ and I know I will never be that smart again.

this should be very interesting to see what kind of disease leads to self aware cognitive decline?

>> No.10999850

>>10998814
media is a drug
t. big brain

>> No.10999858

>>10999822

at least you are being objective and stoic about it. it's the most dignified approach.

Godspeed anon

>> No.10999867

>>10999822
Dementia and cognitive decline are different things. Being aware of cognitive decline in general is the most obvious and common experience whenever it takes place.

>> No.10999957

>>10999822
>strange symptom
It means you’re making it up. I can imagine my cognition is declining too. Unless you can suddenly not function like be unable to say your name or remember how to ride a bike it is class A low key Pyschosis. Except that current guidelines are to tolerate psychosis unless it is a total break with reality so they tolerate your shit.

>> No.10999972

>>10994207
Yo I think you could find Noopept maybe beneficial

>> No.10999983

OP you lying faggot. I read a lot of patient reports and have seen them written. We would probably put “unreliable historian” in your file or some variant thereof meaning that you’re making your symptoms up. Unfortunately the AMA is like way soft these days and thinks if the patients feels sick they are sick (lmao). In the good old days we’d lobotomize your hysterical ass and be done with it.

>> No.11000041

So I would suggest taking your meds for a few years and exercise/get therapy.

>> No.11000065

>>10995758
Who fucking knows though dude, reality is crazy what if it is part of a larger world and this is basically a game we chose to play, maybe we all come here for different reasons and yours was to fight shadow monsters. It's anyone's guess cause no one knows why we're here.

I mean, I'm pretty sure you're just crazy but hey...

>> No.11001817

Bump.

>> No.11002239

kendrick aka compton's human sacrifice...

>> No.11003028

>>11001817


Don't just bump threads anon, at least provide something constructive. A shit post at least. A bump is the worst of all possible posts...