/sci/ - Science & Math

>>10411713
Meth

>>10411713
lsd obviously, learned android programming in a night published the app in the play store the next day.

>>10411713
drugs are for losers

>>10411774
Good to know. *takes drugs*
lmaoooo

>>10411713
Coke and meth, cigarettes help me focus, im a civic engineer in washington

>>10411754
microdosing?

>>10411713
I have literally hired a squadron of people to beat the ever loving shit out of me when I slack off. Productivity is through the roof, although fear increased ten fold. May die of a heart attack soon.

>>10411713
meth
I kept on sucking and taking tranny cocks for 3 days

>>10411713
Paracetamol curing my headache one morning was pretty life changing.

>>10412911
A """civic""" engineer
Lmao cool story

>>10411713
Theanine, phenylpiracetam, phenibut, and adrafinil/modafinil

https://slatestarcodex.com/2016/03/01/2016-nootropics-survey-results/

>>10411753
FPBP

Weed, tobacco, clonazepam, and alcohol, coffee, combined in small doses.

>>10412976
Maybe he works at Honda?

>>10411713
Dmt

>>10413877
>weed
kek, this is how you kill your brain cells

>>10413907
shill

>>10411713
Coffee

>>10411713
I hate Rick and Morty.
Anyways sexual abstinence is as effective as a low dose CNS stimulant. Much more productive when I don't masturbate or have sex and it paradoxically decreases the sex drive as well if you truly are practicing it mentally and avoiding all stimuli and sexual thoughts.

>>10413974
>it paradoxically decreases the sex drive
not so much if you read about test spikes

All of them, I prefer classical psychedelics for creative thought(and in general), nitrous for meditative thought (I didn't understand Peirce until a nitrous binge, Willam James didn't understand Hegel until a nitrous binge) I have been on amphetamines since I was 6, so I wouldnt describe it as life changing but a staple nonetheless, currently taking 60mg dextroamphetamine a day and it really helps. Pure dextro is the best in the opinion of someone who has tried everything (including desoxyn) the racemic mix (Adderall, etc) is shit, the side effects; cardio problems, comedown as well as undesirable mental effects like complusive behavior are mostly agitated by levoamphetamine, which doesn't even produce much stimulation, so Adderall is less effective per mg. Adderall sucks and is completely inferior to dextroamphetamine, the only reason Adderall became popular is because it could be patented, now that the patent has ran out on Adderall they came out with another slightly tweaked racemic mix to push on children. The side effects of Adderall are so bad that I can not take near enough to properly treat myself. Methamphetamine is probably the best but they don't prescribe it in high-enough doses for me. I like cocaine but only buy extremely high quality and often do not have the money. I love Molly for reading literary stuff. I find I can read difficult texts for 12+ hours a day if I take a light benzo or a moderate gabapentin dose with my amphetamine. I enjoy microdosing but prefer to take a perceptual dose every four or so days and an extremely high dose every once in a while. I usually end up innawoods or at a party when I take psychs so I don't have much experience with studying on them. still, calling psychedelics life changing would be a serious understatement for me. I like weed but it completely destroys my drive, it does make me creative as I inevitably retreat into fantasy when I get high(and i do that often)

>>10413974
I find that true for masturbation but not sex. I turn into Superman for a couple weeks after sex.

>>10411713
DUDE WEED LMAO

>>10411713
* chastity
* no alcohol, no caffeine
* early-morning workout
* 1 chapter bible study before bed

>>10414544
false flag

>>10411713
Brain Force Plus, Super Male Vitality, and sometimes DNA Force.

>>10411713
Fasting and some salt

>>10414734
what do you mean?

>>10414735
Stop eating for some days and lick some salt if you have a headache
Cheapest nootropic

>>10411713
I think 3-MeO-PCP permanently boosted my confidence. I highly recommend it if you're getting bullied at work or school or something and you aren't at risk of getting drug tested.

Dihydrogen monoxide take it daily to increase creativity

>>10414177
How tf are you being prescribed Meth?
>>10414963
I hear addiction develops fast though, I can't last for more than a day without it

Desoxyn

>>10411713
Multivitamins/minerals for your specific body condition
Without Rx
You can still get Octodrine (stim) coupled with Coffee and a from of Choline (focus)
Exercise
If you want mood elevation Phenibut (Depressant/Anxiolytic) is still the best
With Rx
Stimulant of choice
>Acid microdose is a meme. Acid is a stimulant and it will make you very creative at the cost of your sanity no matter the dose, more so when coupled with THC

>>10414177
>I have been on amphetamines since I was 6
Dude, you're fucked. Even therapeutic doses of amphetamines for long periods of time (years) permanently damages dopaminergic neurons and your reward prediction/motivation system becomes basically dysfunctional without amphetamines. I take it you're hopelessly dependant on amphetamines considering you've been using since fucking 6 years old.
>methamphetamine
>molly
>benzo
>cocaine
>gabapentin
Again, your motivation/reward system is fucked, not to mention MDMA is also neurotoxic to serotonergic neurons, so I take it you're hopelessly depressed without drugs.
>nitrous
Nitrous oxide literally works by cutting off blood flow to the brain. Abuse inhibits oxygenation of neurons, leading to cell death.

I'm amazed.

>>10411713
I've tried all kinds of drugs. Shrooms changed my life, but learning some basic neuropharmacology has taught me that taking drugs for any long duration is no bueno. Now, I just stick to some quality chinese tea.

Best drug is serotonin, prove me wrong

>>10411713
kill yourself

>>10411713
The worst drug out of all is called life.
I tried it once and would never do it again.

>>10415224
just fucking die already, stupid druggie

>>10414810
>bullied at work
lmao, what the fuck.

>>10415027
According to the literature it can just cause downregulation, and this can be reversed over time.

>>10414810
3-MeO-PCP Psychosis, is it (You)?
The worst part about it my death was that I would live an identity free life it an eternal purgatory where I lacked identity but roamed in a void of pitiful nothingness that was a copy of this world but nothing I did said or interacted withe over would matter and I completely lacked the ability to influence or interact with any aspect of existence, and that this was entirely eternal. I could hear sirens blare unbearably loud at this point and screams and the church bells tolled the same melancholy tone
I screamed and ripped more things from the bookcase throwing all its contents to the floor, exposing the mg scale . I screamed an anguished cry heard by no one and slipped into brief unconsciousness.
When I awoke I heard more sirens and a pounding on my door. I was naked when I woke up and the pounding grew ever louder. I had the perception that the police were after me for an imaginary Meth operation and i imagined the entire community mocking me. the pounding wouldn't cease so I opened up the door and was met with nothing. Nobody was there. The colors outside were incredibly bright and vibrant. After hiding all my drugs on obscure places. I fell out of this state of psychosis and fell into deep mania. I poured soap into my hair and lathered it up and then filled a bathtub with water. I felt on top of the world because i felt my actions had no consequence.
I felt as though nothing I did mattered because I would just die return into the flow of everything again and start anew form unchanged. I sprayed dish liquid all over the walls and ceiling for reasons I can't explain. I passed out in this tub while the front door of my apartment was wide open. I must of been passed out at least an hour. When I got out I decided i would just go outside to air dry myself instead of using a towel despite being completely naked.

>>10415238
Not true. Google 'amphetamine neurotoxicity' and the first results are all NIH studies on the subject. It's been documented for years. Downregulation (which is probably reversible) happens, no doubt, but this is not what makes amphetamines neurotoxic. Here's a PMC study I found describing some of the mechanisms of its toxicity (there are many):
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955986/
>In rodents and nonhuman primates, administration of either a large single dose or repeated high doses of METH or MDMA produces long-lasting deficits in markers of DA and 5-HT nerve terminals (i.e., the levels of a neurotransmitter, its metabolites, biosynthetic enzymes, receptors, and transporters)13-20 while sparing NE terminals.17,21 Amphetamines also produce astrogliosis,22-24 and METH18 but not MDMA21 displays morphological signs of axonal degeneration. Early studies have shown that METH most severely affects DA terminals in the striatum,13,16,18,25,26 whereas DA terminals in the nucleus accumbens, olfactory bulb, frontal cortex, and hypothalamus are minimally affected or unaffected.15, 16 The reasons for this difference are unclear but could be related to the varied densities of DAT in these regions. In contrast to DA terminals, 5-HT terminals in various brain regions including hippocampus, prefrontal cortex, amygdala, and striatum are equally sensitive to the toxic effects of METH.15, 16,20,27 MDMA differs from METH in that it is selectively neurotoxic to 5-HT terminals in multiple brain areas in rodents and nonhuman primates19,28-32; however, it can produce DA deficits in mice.24

>>10415569
good thing amphetamine is commonly used to refer to adderall and not substituted phenthylamines which be the proper term for that study. adderall hasn't been proven to be permanently neurotoxic unlike its methylated alternative meth which is directly neurotoxic due to sigma receptor activity

>>10411753
/thread

>>10415233
hs never ends and especially so for ugly and good looking people

>>10415596
It's called real life.

The ugly and slow guy will get you all killed in the wild.

>>10415569
A psychiatrist (see MD) told me it's not neurotoxic in the ammounts prescribed.

>>10415588
Adderall is literally amphetamine. Amphetamine and methamphetamine have identical mechanisms of action. And no, amphetamines is apter than substituted phenethylamines, which is a broader term that encompasses amphetamines but usually only refers to phenethylamines that are not amphetamines. There is a breadth of data on amphetamine's neurotoxicity, and at this point you're just falling prey to cognitive dissonance and confirmation bias.

don't do it anons drugs are for fagnuts

>>10415634
this is literal basic pharmacological information m8
https://en.wikipedia.org/wiki/Methamphetamine#Neurotoxicity_and_neuroimmune_response
>Unlike amphetamine, methamphetamine is directly neurotoxic to dopamine neurons in both lab animals and humans.[22][23][24]
you should be able to link at least 3 studies if you really think that because there's 3 studies at the bottom of the wiki page i just linked
stop spouting buzzwords that you have no idea what they mean
you're falling prey to the fallacy of being legitimately retarded

>>10415613
The latest literature (see hundreds of MDs and PhDs) disagrees with you and your one doctor. I literally laid it all out and I encourage you to look into it. Psychiatrists are full of shit, by the way. Their job would not exist if they didn't prescribe drugs, they are literally incentivized to be partial towards prescribing at all costs.

>>10415645
>links a Wikipedia article
>doesn't google 'amphetamine toxicity' to immediately see dozens of studies
>you're falling prey to the fallacy of being legitimately retarded
kek

I'm done responding to people who in denial b/c they've been prescribed neurotoxic drugs all their lives.

>>10415659
alright

>>10411753
this
>>10413200
cute

Ashwaganda and Tongkat Ali

>>10414644
this is bait but lowkey on point

level 1: caffeine
level 3.2: cocaine (too much euphoria)
level 5.5: speed or basic amphetamine
level 5.8: modafinil
level 10-15: ice meth

>>10413890
This

>>10415634
How do you make your meth

I've found that singular doses of LSD enhance motivation long-term more than any stimulant I've taken.

>>10415659
I believe you anon.

I've been prescribed Methylphenidate (30mg, which is a low dose I guess), and with prolonged use I certainly notice neurotoxicity. It's not good.

For me I think it is reversible, but maybe I've done mild damage. I should only be taking it for exams i.e. for performance enhancement.

>>10415027
>Nitrous oxide works by killing brain cells
Nitrous oxide is one of the few gases that is psychoactive.
It's high is best when mixed with oxygen (not taken how those raver British kids do it).

>>10414644
This but swap the Bible for Siege.

>>10411713

Aspirin, coffee.

>>10415984
ritalin is literally a reuptuake inhibitor which is the least "neurotoxic" class of drugs by far. they don't even come close to monoamine releasing agents like amphetamine or mdma. even cocaine isn't close then neurotoxicity of meth even though it's an immensely powerful reuptake inhibitor

>>10414741
what's the science behind that

Anyone tried Salvia?

>>10415984
define prolonged, for how long?

>>10416320
2 years.

>>10413974
>>10414187
Is there any physiological difference between sex and masturbation?

I enjoy masturbation a lot more than sex. Probably because I masturbate to specific fetishes while sex is just vanilla normal stuff.

I don't feel different after sex compared to after masturbation. In fact I always feel more motivated after masturbation to work on my paper more while after sex I get kinda sleeping because I'm laying in bed anyway and usually take a small nap or just keep laying and talking with my girlfriend about bullshit.

>>10416516
no breaks? obviously you're a fucking idiot

>>10412922
no

>>10416522
Nah I lied for some dumb reason.

I've started abusing it over the last few weeks. Yeah I'm a fucking retard.

I usually take several days off, sometimes up to a couple of weeks.

I'm going to discontinue tomorrow until I return to baseline. I don't expect it to take too long. Then I'll only take it for exam prep etc. Only need 5mg per study session.