/sci/ - Science & Math

>>10144489
They work - plenty of chatter about them over on plebbit

>>10144489
just take amphetamines

>>10144568
This. Nootropics are borderline placebo.

>>10144489
phenylpiracetam was used by the russian space agency and has probably the most scientific rigour out of all nootropics
https://en.wikipedia.org/wiki/Phenylpiracetam

realistically if you want something that works amphetamines or most dopamine interacting drugs on a light ish scale like that. amphetamine works by releasing dopamine and ritalin (methylphenidate) works by inhibiting dopamine from going back into its cavities btw

>>10144596
>>10144568
Non addicting substances only pls, I have addiction problems

>>10144615
you probably shouldn't be looking for drugs that people take daily then

>>10144621
I can get off caffiene but anything in the nicotine+ level of addiction potential is a nono for me

>>10144625
i mean caffeine has more scientifically verified nootropic properties than any of the piracetams have. other than that you're looking at edge drugs like memantine with its nmda receptor upregulation but it isn't going to make you a super human and you probs won't notice a difference. maybe try cbt at your local mental health unit

>>10144628
I've been looking into creatine, caffeine + l-theanine, and microdosing 20ug 1P-LSD on days I am programming. I can get my hands on all of that easily, have research I can pull up on Scholar (minus the LSD but the large amounts of anecdotal evidence points to a benefit in creativity), and I know I can handle that stuff. I'll look into phenylpiracetam and I might throw in Saint John's Wort but I worry about serotonin syndrome.

What are your thoughts on this stack?

>>10144638
I think you're wasting good LSD working as a wageslave, and should instead take higher doses irregularly to further yourself as a person

>>10144639
It's 1p, as long as the friendly Canadians are still operating I should be fine. I'm a college student, so for now it's to help me learn. I was gonna get 100ug tabs so I can volumetrically dose. I also plan on keep a couple to drop for psychonautic purposes.

>>10144638
Whats creatine supposed to do? I thought this was a bodybuilding suppllement ?

>>10144645
I lift and also there's a few studies I found that said it's promising for boosting cognition by raising creatine levels in the brain or something. I have a big tub I infrequently use lying around anyways so why not.

Take Modafinil. Shit works

>>10144657
I hear the withdrawal sucks

>>10144638
lsd is non addictive except in very rare cases. my dad's side has all tried lsd and is very prolific in science and i and my brother do lsd a lot (he waits 1 week for tolerance, i wait 2 usually). serotonin syndrome is a mega meme and it's been blown out of proportion since one of the only deaths associated with it (libby zion).
https://www.medscape.com/viewarticle/776124
this article was about buprenorhpine (outlier opioid) and how serotonin syndrome was extremely common in people taking it. the worse you'll get from saint john's wort in terms of serotonin syndrome is perhaps a headache and that's assuming you take some of the drugs on the serotonin syndrome wikipedia with it
i have no problem with microdosing lsd even though i have no experience with it. as well 1p-lsd is a supposed prodrug to lsd and is supposed to be pharmacologically inactive. amusingly, this mimics the illegal magic mushrooms (prodrug to 4-ho-dmt). if you're worried about tolerance to i'd recommend microdosing a tryptamine as opposed to a lysergamide as the tolerance is highest from lysergamides from my research. lysergamide has 12 days to "baseline" average but shrooms can be as low as 3 days to baseline from a standard 4 gram dose. chemlogix and rechem are legal drug vendors i use. chemlogix sells only psychedelics and rechem does sell stimulants but the class (phenmetrazine analogs) is supposed to be the most addictive stimulant to date so i'd avoid. rechem also sells a liquid 1p-lsd so it would make microdosing easier but is probably quite a lot more volatile than normal lsd tabs or micropellets. as well, wrapping your tabs in tin foil and putting them someplace dark and cold is the way to preserve your tabs if you were to save them for a long time

>>10144668
This will get removed because source talk but thank you for the advice. As for your guys, are they USA based? I hate dealing with the international shipping from the Canadians.

>>10144674
i didn't know mentioning sources for legal drugs was not allowed. i see this is now reddit.
reddit.com/r/canadarc
and they're canadian based as i live in canada and health canada has seemingly stopped banning drugs the current legal drugs (i believe they realized the research chemical crowd doesn't die)

>>10144679
I've been janny'd for namedropping the Canadians before on a different board so I don't want to get thread nuked again.

>>10144680
On a separate note, would a volumetric pipette be a good investment for this activity?

https://www.bravermantest.com/
here's a website to very loosely diagnose neurotransmitter chemical balance (you want all the numbers to be close together) as well as suggested supplements to fix any imbalance
>>10144683
i don't see why not. from what little i've read about microdosing lsd they dissolve tabs (of a known dose) into a certain ml of water then only take the dose they desire.

>>10144660
Nope.
Dont take it regularly, just when needed. It works for me. I can concentrate and stay focused for hours with it.

Are there vitamins/minerals a person is most definitely deficient/not optimal in that are worth supplementing?

>>10144615
Then try green tea, especially Japanese green tea. Go got Sencha since Macha is too bitter.

>>10144698
not that i know of. nootropics and even pharmacology are very new things so nobody really knows what's going on really. anyway, i'm going to bed now as it's 2 am. hope i helped

>>10144707
I'm not a pussy I love my matcha

>>10144697
Noted

>>10144657
Literally all placebo.

>>10144707
>sencha is too bitter
stop steeping it for 15 minutes in boiling water and you won't get so much bitter tannins
You do it right and it should have a light sweetness to it.

>>10144615
Methylphenidate is non-addicting

>>10145390
Haha, no.

>>10144638
>20ug
I don't know the strenght of your legal but not so legal LSD but 20ug is far too much. At roughly 25-35ug I felt some of the effects of a trip during my peak. Stick to 10ug.

>>10144657
This OP. Phenibut, piracetam, modafinil and LSD MD are good nootropics.

>>10146601
>>10144657
>modafinil
Where can I get this that doesn't cost an arm and a leg but is also of a higher quality?

>>10144489
I take Phenibut as needed. It basically gives some effects similar to alcohol like social inhibition without all the nasty side effects. It makes me more sociable. Music sounds better. My libido is increased. My mind feels more free and not limited. It gave me the balls to ask a girl out. Gabapentin is another one that makes more more productive and focused.

>>10146601
Illegal dosing is absolute garbage 90% of the time.

>>10146601
phenibut is extremely addictive and he specifically said he has an addictive personality. as well, you get benzodiazepine withdrawals if you build a tolerance and don't taper off. i messaged a dude who was going on his third year of benzodiazepine withdrawals from taking 30 grams of phenibut a day then stopping cold turkey. some people even want phenibut regulated but it doesn't actually kill people and is used in production of other drugs (like phenylpiracetam as it happens)

>>10144489

>nootropics
We don't yet understand how the brain works so there is a lot of risk. Even Piracetam and Noopept have been shown to damage developing brains of rats. Our brains develop until age 25 so if you use nootropics you turned your brain into a science experiment.
>https://www.ncbi.nlm.nih.gov/pubmed/16224581

>>10147013
>30g of phenibut
I think you accidently added a 0, lad. Normal doses are like 1-3g, with 3 being a lot already.

>>10147391
hence 3 years ongoing withdrawal. not sure why he'd lie about it to me but here's the message he sent me

Hey Jesus_Man, thanks for messaging me. At this point in time my anhedonia hasn't gotten better but my cognitive problems have been slowly improving. It took 9 months before i noticed slight improvement with my cognitive problems and it took 14 months before i noticed major improvements in cognition. Right now im trying to stay away from all drugs until i heal, i have talked to a few other people who quit a heavy phenibut addiction cold turkey and most of those people said the anhedonia took over 2 years to go away. Unfortunately anhedonia is usually the last symptom to go away and from what i read phenibut paws can resemble benzo paws for some people so this may take awhile before it goes away.

Thanks for your advice and for telling me about that microdosing study, thats interesting and terrifying that microdosing did that to apes. In the future if i dont get better i may try microdosing but for now im probobly going to wait until the 3-4 year mark before i try anything since im paranoid about making my mental health worse and i want to see if my brain just fixes itself.

Thanks for messaging me, i appreciate it. Do you take phenibut and if you do whats thr dose you use?

Nootropics are a meme in the sense that you're spending hundreds of dollars on something that might give you a 0.5% boost on a good day, when you could just buy something that actually has a significant effect for much cheaper. It's basically the equivalent of spending $300 on SARMS and research chemicals when you could have just bought an actual steroid cycle for a fraction of that.

That said, there are a few things that are actually worth the money. Modafinil, Phenibut, Tianeptine, ALCAR and Phenylpiracetam all have decent use cases. Correcting common deficiencies in Vitamin D, B12, Omega 3's etc is also worthwhile.

>>10147437
>Correcting common deficiencies
don't forget c0q10 deficiency. I almost died from cardiovascular disease if I didn't get this

>being such a brainlet you need drugs to focus and then more drugs to sleep
imagine the thought of being this intellectually impaired.

How about strattera?
adhd-passing-nearby

>>10144638
what vendor do you use? I'm in the same boat struggling stay motivated. tried casual searching for 1p with no avail, seems to sketch for me.

>>10144698
>>10144711
Depends on your region. Third world people tend to lack things like iodine unless they have a lot of seafood in their diet.
For a standard first-world 4channer Vitamin D would be the big one. Magnesium is also a common deficiency. Zinc to a lesser degree. Depends on your diet.
Omega 3/fish oil can be useful for head injuries but supplementation in healthy people hasn't shown any significant effects (except maybe in growing children).

>>10145390

>>10144489
>Are nootropics a meme?
Lrn2meme fgt pls

>>10147543
starts with an L and ends in ysergi

Plebbit loves them too

>>10147380
W2c prl

>>10146688
how do you dose? do you cycle? how does it mix with weed?

>>10144596
Where can I get phenylpiracetam

>>10147013
Good to know. It's one of the drugs I hear a lot about but don't know enough about except the positives. I was exposed as a scam.
>>10146630
I get it from SunPharma. Sure, it's indian but I don't see a difference between it and overpriced Western companie's modafinil. Deepdotweb should lead you to the right places where to get it. CN works too but thats a major rip off.
>>10146820
If you mean that illegal LSD is bad then you just don't know how to use TOR. If you missread my post what I meant is that 1-P LSD is LSD but they added a chemical bond to make it not the same but still the same and way more expensive.
>>10149669
Literally sold on amazon for 40 maple leaves a bottle.

>>10146688
Phenibut kind of sucks man. Even when I started taking 3-4 grams straight away it really didn’t help that much, and as soon as you don’t take it for one day, seriously heavy depression like I’ve never felt before sets in, then on top of that weeks of insomnia

>>10149428
not him but you either take pills of the stuff, place the powder in the back of your mouth then swallow according to an internet source, or stomach the unnatural citrus flavour with water. idk how it mixes with weed because i don't really feel phenibut at all kek.
>>10149669
one of the canadian vendors in this thread sells it on a price per gram basis. i'm sure a lot of places sell it if you google phenylpiracetam vendor

>>10144489
>Gimme some citations for which ones are good and which ones aren't.
Phenylpiracetam and L-theanine are the best ones from my experience. L-theanine is good for wakefulness and thinking more clearly.

>>10144489
What you're looking for are often referred to as herbs. Go to the warosu sci archive and search for past nootropic threads.

>>10149703
What I meant to say was that LSD I get from illegal means is usually dosed inaccurately and I'd rather get 1p for a little more because I know my source doses accurately. Unless you can name me a reputable seller and guarantee me that 100ug is 100ug than I'll go for it.

>>10144489

Anyone tried Mucana pruriens ?

>>10150030
What makes you think that 1P-LSD is accurately dosed? Is it because it's made by chemists? If so you should know that a lot of good producers of LSD are chemists. Making LSD is complicated and dangerous and is often done by chemists. On TOR I find that any seller that has a very long bio and a good description of their process sell good products. Otherwise if you dont want to leave the clear net or don't care about price then have fun with 1P but I pay 3$ per tab.

>>10150604
Are they us based? Would it be less likely to be seized than 1p?

Smoke cigarettes, its proven that nicotine improves working memory significantly.

>>10150794
darkweb sales ship their drugs hidden in other stuff. 1p-lsd can get shipped in its form without getting seized here in canada that is. micropellets are the better way to dose fully btw as they dissolve in under a minute in your mouth

>>10146688
I found usage of phenibut for 2 to 4 days per week, 500mg - ~750mg, to be fairly destructive. It "overstructures" memory and creates detachment and apathy.

It really does have to be as needed, but it's benefits are so profound and seductive that it's easy and reasonable to slip into chronic use. It normalizes my heart rate and blood pressure for example, my endurance is greatly increased and I don't have cardiovascular mediated fatigue.

The social apathy is kind of a downside.

>>10149708
That's because you're taking an absurd dose.

>>10150511
Doesn't help me with anything, and easily makes me sick if I take it with other things. Never found a strong benefit. Doesn't even arouse me.

>>10147380
>nootropics for anxiety

>>10144568
this, nootropics are hot garbage real stims are the only thing that actually does anything
>>10144615
if it's not addictive that means it doesn't work
>>10144698
vit D. ask your physician to get bloodwork done just say you're abnormally tired if you need a reason

>>10147380
>>10151650
>source = reddit survey
Into the trash it goes.

>>10151650
so basically
better nootropic = more anxiety

>>10151659
It's cute that they're trying to be scientific though.

>>10150794
Purchase from a seller that is located in the US. No chance that the package is opened unless it is suspicious which I can assure you they make sure it is not.
>>10151674
Phenibut is great as a nootropic.

>>10151705
>nootropics are supposed to improve cognitive function
>phenibut decreases memory function and probably makes you generally slow as anixety reducing drugs tend to do
how is it a good nootropic?

>>10144489

Caffeine enhances your memory:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107567/

>>10144489
they work but it's a minimal effect

exercise is unironically better

Can someone redpill me on Amentoflavone? I've started taking it for dp/dr as it blocks Kappa opioid receptors and it inhibits GABA A as well. It's supposedly also a vasodilator and increases muscle calcium just like caffeine. I don't have much of it, would snorting it increase bioavailability?

>>10151720
It increases motivation in a similar way that modafinil does it and it makes you less anxious. If you are someone like me who spends a lot of time chewing on his nails/fingers when studying this can make you waste less time and I think the motivational boost is self explanatory. It isn't the best but if those are your issues it will help you.

>>10151872
Read: https://en.wikipedia.org/wiki/%CE%9A-opioid_receptor#Function

Kappa antagonists come with the risk of ventricular tachycardia, so refrain from high doses and non-oral consumption.

>>10144596
I can vouch for phenylpiracetam. It wont do anything crazy but it will literally be impossible to sleep with it.

>>10152343
Yeah, I think that's why they suspended JDTIC. Didn't know it was a common feature in kappa antagonists. Still, theoretically, how much stronger would AF be if taken nasally?

How safe is l theanine? From what I've gathered it's basically completely risk- and withdrawalfree, even more so than regular coffee, but it would be nice with a second opinion.

>>10152351
>Still, theoretically, how much stronger would AF be if taken nasally?

Not much probably, since the main issue seems to be the blood-brain barrier.

I can't directly link to it here due to the spam filter, but look for a paper titled "Brain-to-Plasma Distribution Ratio of the Biflavone Amentoflavone in the Mouse" and access it via http://sci-hub.tw for more info.

>>10152364
>How safe is l theanine?

Very. The German "FDA" found its LD50 to be > 5 g Theanine per 1 kg body weight.

https://www.bfr.bund.de/cm/343/getraenke_mit_isoliertem_l_theanin.pdf (Text in German)

>>10152386
Lethality is one thing, fucking with your head is another, isn't it?

>>10152393
>Lethality is one thing, fucking with your head is another, isn't it?

Copy and paste the whole paper into Google Translate or something for more info.

Otherwise: https://www.ncbi.nlm.nih.gov/pubmed/16759779

There is no evidence for either beneficial or adverse effects of theanine.

>>10147380
This list is interesting, but self-contradictory: Selegiline (upper third) is the same as L-Deprenyl (second from the bottom).

https://en.wikipedia.org/wiki/Selegiline

>>10151611

Yeah it does kinda make me sick. Hard to tell if it works at all with these things

>>10144489
They won't make you smarter, they just make your brain utilize itself better for it's purposes. Being smarter may be side effect of that process. If you are really dumb, you'll be dumb, just way more smarter dumb.

>>10153139
This makes no sense lmao

>>10153209
"More powerful car, driver is same idiot"

>>10153239
lol no

>>10144707
Matcha is the way to go my friend. It has high levels of caffeine and L-theanine, just what you want for an optimal studying experience.

>>10153239
This. Supporting the brain's antioxidant systems is the most important, adding a acetylcholinesterase inhibitor or acting on some other system comes second. But a constant looming shadow should be the idea that you can reword how you think, and the architecture of your mind. Those are the greatest opportunities for gains.

>>10154574
>reword
rework*

CEREBROLYSIN

Proper rest
Balanced nutrient rich diet
Regular exercise

BRITBONG HERE!!!

As you might be aware, my faggoty country has banned Smart Drugs.

Any fellow brits, or those studying here know how to get any smart drugs in to the country?

PS I am a postgrad at Leeds, in case you happened to know any local sources.

>>10155276
Going abroad and getting back with drugs?

>>10155276
.onion

>>10155400

> I am far to poor, and far too busy to set foot out of the UK.

>>10155401

Onion? What is that and how does it work?

>>10155406
"deepdotweb"

>>10144489
Anon, there is exactly one "nootropic" and that's methamphetamine.
The rest is kiddie shit and ultimately a joke.

Be sure to recrystallize your meth and determine the melting point before use, though .

>>10145279
Nope.

>>10152393
>>10152466
technically, assuming it's like other gaba drugs (alcohol, phenbiut, benzodiazepines, and bariturates) it could in fact be detrimental to your mind in ways that aren't perceptible. of course, no super detrimental effects have been found just like in caffeine technically

>>10154574
this. i recommend sarin gas for acetlycholinesterase inhibitor. realistically if you're scared of "brain fog" then you should avoid acetylcholine drugs as i've seen the most reports of brain fog from them on the internet

>>10154600
this is the strongest drug i've taken to date for brain performance (calorie restriction fixed my drug fucked memory)