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/sci/ - Science & Math

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10086571 No.10086571 [Reply] [Original]

How much can your natural dopamine pathways be suppressed? What substance(s) can be used to achieve this?
I have a theory that dopamine more than anything else is what is currently holding humanity back from its full potential. The wretched compound is what keeps our minds full of primal distractions, taking up valuable mental processing power that could be dedicated to scholarly pursuits. Knowing an official experiment of this degree would never be conducted thanks to "ethics" boards, I'm opting to experiment on myself, but I need help getting started.

>> No.10086573

>>10086571
that's how you give people Parkinson's

>> No.10086574

>>10086571
Good luck learning anything with a stunted reward system.

>> No.10086577

Worst theory ever 10/10

>> No.10086579
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10086579

>>10086574
>needing chemical rewards to maintain the pursuit of knowledge.
>>10086577
nice argument

>> No.10086660
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10086660

>>10086579
>">needing chemical rewards to maintain the pursuit of knowledge."

>> No.10086671

>>10086571
>Killing the one brain system responsible for motivation
Good luck living with what will essentially be self-induced depression

>> No.10086680

Pharmacological agents increase tonic (= baseline) dopaminergic activity.

Motivation and anticipatory hedonism require phasic (= pronounced and fast, yet short-period increases from baseline) dopamine function.

OP btfo.

>> No.10086782

Jesus, this thread is full of tards (especially OP) who have no idea how reward pathways work. Dopaminergic reward is what motivates you to do anything, without it you will literally be unable to feel rewards of things as simple as eating food. You will not "be dedicated to scholarly pursuits" when you are literally unable to fulfill baseline needs, much less develop healthy habits, have any motivation for anything, or pursue goals of any kind. Motivation and reward, even that which is beneficial, is mediated via dopamine.

There are drugs that will permanently damage dopaminergic neurons, and as a result, cause severe depression and symptoms of Parkinson's disease. We know what happens when people destroy their dopaminergic neurons, theres no need for you to do it unless you want to fuck yourself over for life.

>> No.10088074

>>10086571
OP's pic is the worst way to think, even for Hulk...

>> No.10088113

>>10086579
>Requiring any physiological substrate to instantiate psychological and cognitive processes
>Needing afferent and efferent neurons to detect and interact with environmental stimuli.

Does /sci/ even into pre-established harmony and Cartesian dualism?

>> No.10089663

>>10086680
>brainlet who never tried meth

>> No.10090120

>>10089663
long term consumption leads to decreased, rather than increased motivation.

now guess, what's the mechanism behind that?

>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699967/