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2023-11: Warosu is now out of extended maintenance.

/sci/ - Science & Math


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10028031 No.10028031 [Reply] [Original]

Thoughts on biohacking? Do you think it's a meme? Is there potential in significantly improving performance through drugs or other biotech methods

My routine:
>Meth - 10-15mg IV daily
All studies show beneficial effects at such a dose and very tolerable safety possibly even in children.

>GW501516 - 10mg oral daily
Despite one meme studies were rats received 1000x the dose everything else is in support of it's physical performance, anti diabetes, lipid profile improvement, neuroprotective,... effects

>Ashwaganda - 300mg daily
Very promising literature around it. Haven't dwelled into enough to make any definite statements though

>Vitamin D - 50,000IU per 2wks/month/2months
At such doses your body can regulate optimal release throughout weeks/months

>NAC - when feeling like it
Can help with stimulants side effects(?), breaks up mucus to help with breathing, and has other potential benefits
Sustainable highs/drugs
>Baclofen - 10-30mg
Muscle and nerve pain

>Phenibut - 1g per wk, 2x0.5g per wk or 2g every 2-3wks
Use on long work days or interviews or w/e

>Diazepam - when in real need of a benzo
Depending on your use diazepam can have one of the best therapeutic potentials although there are newer benzos that might not cause tolerance but I still can't have access to them

>> No.10028041

>>10028031
-Gotu kola
-Rosemary
-Ginkgo Biloba
-Ashwagandha
-Bacopa Monierri
-Theobroma cacao
-Celastrus paniculatus
-Hemidesmus indicus
-Lavender
-Angelica sinensis
-Angelica archangelica (Both angelicas increase tactile sensitivity and sexual pleasure when applied topically (aqueous extract) or taken internally)
-Hawthorn berry
-Eleuthero
-Guarana seeds

A note on the above, care should be taken not to combine too many acetylcholinesterase inhibitors.

More caution:
-Wormwood (With MAOIs, and dosage)
-Shatavari (Highly estrogenic)
-Panax Ginseng (Estrogenic)
-Kava (Plant part used, fungal contaminants, believing one has noble variety when they have tudei)
-Phenibut (Overuse)
-Mucuna pruriens

And finally the most effective approach for the modern world. Stop fucking up your body in as many ways as possible.

>> No.10028048

>>10028031
My biohacking routine is enough sleep, exercise and not being fat fuck

>> No.10028052

>>10028048
Not good enough.

>> No.10028058

>>10028048

Being fat isn't something you can control most of the time. And if you were fat many of the compounds listed are evidence supported ways to lose fat unlike the exercise and diet meme
>inb4 politically/emotionally driven statements

And sleep + exercise could both be improved by and done alongside many of the compounds listed. The two are mutually exclusive. Only an idiot would ignore freely available information that could significantly improve him well being and functioning for the "natural"/"traditional" alternative

>> No.10028063

>>10028058
>And if you were fat many of the compounds listed are evidence supported ways to lose fat unlike the exercise and diet meme
If this is the topic, I'd have to emphasize theobroma cacao and add yerba mate to the list. Both combined with light caloric restriction (or simply better diet), will cause you to lose weight. Restriction of fats is also a cause for people failing to lose weight, you need to kick lipolysis and that whole pathway into high gear.

>> No.10028065
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10028065

>>10028031
>biohacking
Im quite interested in the topic of transfiguration myself. When I do it, I usually jump onto a human(heas, specifically) and claw myself tight into it, with the claws having a strong sedativum. While it is not entirely dead, I begin to grow little tubular cells into his brain, where I use primarily the primary visual cortex for information gathering and the thingy which controls its movement. I inject my chemicals so that the human doesnt die. funnily enough, this leads to it being transfigured and looking quite.. interesting.

Here, Ill show you an art where such a transfiguration takes place.
https://www.youtube.com/watch?v=6gYBXRwsDjY&t=229s

>> No.10028066
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10028066

>>10028065
sorry, meant to say "head", not
>heas

>> No.10028067

>>10028041
It isn't per se.

The main argument I have against traditional exercise + diet weight loss are as follows:
>Compensatory behavior
>Appetite increases many folds to make up for caloric restriction
>Metabolic changes following calorie restriction

Weight regulation is comparable to thermoregulation. Your body has many ways to avoid dropping your weight down. Meaning that once you become fat it's very hard to lose it.

I have only been able to find one study which may hold some promise for weight loss using exercise and diet only. In that study patients had refeeding periods that prevented their metabolic rate from changing. But it's a single study and many other factors need to be accounted for.

>> No.10028074

>>10028067
Not sure if you intended to quote me there.

>>Appetite increases many folds to make up for caloric restriction
This is caused by more adipose, and therefore more leptin production. The individual must either have willpower and focus, or apathy, and accept that it is an illusion.

Theobroma cacao is a strong appetite suppressant, and directly acts to convert white to brown adipose, biases metabolism towards lipolysis and ketosis with or without low blood sugar. Yerba mate reduces inflammation and has certain novel actions of its own.

>>Metabolic changes following calorie restriction
This is necessary.

Weight management should never be put on the level of thermodynamics. The body is a machine and is literally bound by physics, but what stems from such a perspective is rarely useful and often detrimental.

I've never been overweight, but using the method mentioned I went from 130 lbs to 85 or so in the space of a year. I remained highly functional, for the most part, throughout. Some one living a different kind of life with real excess fat to lose would likely fare even better.

>> No.10028077

>>10028074
quoted you but in agreement and reference. Just wanted to emphasize some points for anyone who doesn't understand the challenges of weight loss

>> No.10028159

Daily
>Venlafaxin 225mg
For Serotonin and Noradrenalin (focus)

>Theanin + Coffein
Wakey-wakey

Sometimes
>Pseudoephedrin 60mg
For endurance when coffein doesn't help anymore

>> No.10028257

I'm all for it
I just need to set aside some time to read up on more literature

You ever consider Dr Rhonda Patricks 3lb shake? She has a video that breaks down the components and their research

>> No.10028288
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10028288

>ctrl + f
>no vitamin K2

Sad!

>> No.10028778

>>10028067
>>10028052
>>10028058
yeah but exercise, sleep and not being a fat fuck is natural for normal people so they dont really have to do anything extra. also side efects of prolonged intake of most compounds is unknown unlike "lame traditional way" which is known for the benefits far outweighing risks

the only worthwhile, well researched thing worth taking is coffee which everyone takes anyway

>> No.10029685
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10029685

What do you think of my regimen?

>> No.10029697

>>10028058
I had a thyroid tumor everyone things i am a normie fattie, then I out run them and out lift them in the gym!

>> No.10029710

>>10028058
>being fat is not something you can control
t. fat sack of shit with no motivation or ability to eat a proper diet

>> No.10029730

>>10029685
10/10 anon this is peak performance

>> No.10030324

>>10029685

its so advanced i dont even understand it.

>> No.10030330

>>10028031
Drug using is not biohacking.
Because you actually damage the body and they actually reduce productivity

>> No.10030525
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10030525

>>10028778
Why don't you go live in the wild and hunt animals. A lot of technological concepts are unnatural and can greatly impact your health and have little research done on them. Simple things like shopping for food instead of hunting it defies billions of years of evolution and exposes your body to a completely new experience. Many drugs have fairly well understood mechanism and enough research done on them to experiment with. By your logic you shouldn't cross the road because there is a risk of getting hit by a car.

>>10029710
Annoyed that science defies his predetermined political beliefs. The meth and GW501516 have left me with almost no fat on my body. But nice ad hominem.

>>10030330
Your body is very comparable to a computer. It functions on hardware (excitable tissue/cells) signalling to one another. If you agree that drugs can have an influence on these signals then theoretically speaking there is potential for improving your body function. Biohacking is simply using technology (drug or otherwise) to modify your functioning.

>>10029685
Nice estradiol

>>10028031
Forgot to mention a few:

>Melatonin - lowest dosage attainable before bed
Very useful especially if you use any sort of stimulant that can impair your melatonin release or if you have insomnia

>VLD naltrexone
Has promising studies on it but didn't see any noticeable effects on myself. I don't currently take it.

>CBD oil
When smoked can quench the need for weed without causing any side effects such as memory loss or sleep issues (stops melatonin release).

>> No.10030535

>>10028159
>pseudoephedrine
Ephedra is used to make meth. The difference between the two lies in that meth acts almost exclusively centrally while ephedra/coffee/adderall/other stimulants have a lot more peripheral (uncomfortable side effects).

By using these you are basically making yourself uncomfortable for a slight central effect. Meth has such a high abuse potential because it enables users to take insane doses that cause euphoria without the body load. But at the equivalent dosage it's a much more stable, long lasting, and therapeutic compound.

tl;dr switch your ephedra for more centrally acting compounds like dexedrine or meth. Just be carefuly when combining with antidepressants

>> No.10030613

>>10030535
You're underestimating the obvious. Where the fuck can you get it and you're lucky if it's not made out of a Gatorade bottle

>> No.10030661

>>10030613
That is a fair point. If you can't get the best then you can tend towards compounds with fewer peripheral effects depending on availibility (meth>dexedrine>adderall/ritalin>speed).

If you are really worried about the quality of the product you could ship it for a test. Otherwise you could check it's solubility, residue, flame, reagent test, effect and estimate the quality. Also with dark web markets you can also use the reputation, and reviews of others. Depending on your area you might have a decent supply.

>> No.10030935

>>10030525
Can you recommend what device vapes cbd oil, and where I can buy cbd oil in easy to vape batches?
or do I just drip cbd oil from amazon into something?

>> No.10030940

Great thread

You fags have lit sources though? An author or journal would suffice so o can look shit up using school database.


Particularly interested in natural (plant) products

>> No.10030959

>>10030935
Loads of variable answers for your questions. But I'll tell you how I personally do it.

1. I am unsure if smoking is better or even safe but I can't see why it wouldn't be since smoking weed has never been shown to harm your lungs and weed would contain oil to some extent(?)

2. Reddit is your best best for finding reputable cbd oil sources in your area

3. Personally I make a joint out of herbal fillers (marshmallow leaves and a tiny bit of marigold petals) and drop some cbd oil inside it. I then smoke the oily roll slowly. I'm sure you can google how to vape cbd.

You might really enjoy cbd or you might feel let down. Make sure you calculate the dose per ml or drop of the oil you get because you might be taking too little. It's price is much cheaper than smoking but it isn't comparable to the low price of supplements and what not. go from 10, 30, 50, 80, 100, 150, 200..., 3000 even. Whatever dose works for you. The upper limit is pretty far

>>10030940
Why are you particularly interested in natural plant products? Why are you not interested in the optimal products? Plant products can be as harmful and usually(?) more harmful than synthetic ones.

If you want sources on anything then please ask about it. Each item could have hundreds of sources. It would be too difficult.

>> No.10030974

>>10028031
This nigga can't be serious

>> No.10031183

>>10028058
Something YOU can't control you fat piece of shit. Stop making excuses

>> No.10031236

>>10029685
>LDS Microdosing
if you're gonna be a fucking mormon go all the way bro

>> No.10031261

>>10028052
Actually it is. Doing the OP is how you fuck your body up because of overabundance.

>> No.10031299
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10031299

>>10031183
zzz another ad-hominem reply

Appetite increase :
>"On average, energy intake increased by ~100 kcal/day per kg of weight lost—an effect substantially greater than the ~30 kcal/kg/day changes in energy expenditure observed with 10 to 20% weight loss in subjects with obesity."

>this is on obese subjects we can assume that weight loss is a lot more difficult in overweight subjects(?)

>figure shows how appetite remains significantly increased and energy expenditure reduced even after going back to baseline caloric intake

>www-ncbi-nlm-nih-gov.manchester.idm.oclc.org/pmc/articles/PMC5108589/

Compensatory subconscious behaviour:
>www.ncbi.nlm.nih.gov/pubmed/23470300

Metabolic changes:
>www.ncbi.nlm.nih.gov/pubmed/10797147
>www.ncbi.nlm.nih.gov/pubmed/19660148
>www.ncbi.nlm.nih.gov/pubmed/20054213
>www.ncbi.nlm.nih.gov/pubmed/11430776

Large 2014 meta analysis including 37+8 studies and 7788 subjects:
>Overall effects of behavioural/lifestyle interventions, both with and without orlistat, on weight loss maintenance are small, and further research needs to focus on increasing effectiveness of interventions

>www-bmj-com.manchester.idm.oclc.org/content/348/bmj.g2646

Counter argument:
>Studies show that refeeding/cycling diets can help with many of those complications. But large studies replicating the long term weight loss and maintenance at a reasonable magnitude for such diets and looking at all the factors above are yet to be produced.

Conclusion:

The current literature does not support the efficacy of exercise + diet induced weight loss and maintenance.


>>10031261

What do you mean by overabundance biologically speaking? That's very vague. If you believe there is any harmful interactions or another harmful effect from being overabundant then please elaborate. With evidence preferably.

>> No.10031327

im going to try stevia. i may mutate into a super villain. i will report symptoms of my mutation like potentially ibs or erectile dysfunction if they are observed

>> No.10031356

>>10031327
update the packet of stevia seems to have made my tea taste like chalk. my mouth has a film of a unknown chemical lining it now. i have gambled it all and lost...what have a i done

>> No.10031515

>>10031261
Toxic environment. You can't pretend you're living in a place, or the way, our bodies evolved for.

>> No.10031518

>>10028058
>unlike the exercise and diet meme
worked for me, big guy.

>> No.10032287
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10032287

>>10031518
Anecdotal + "big guy". 4chan /sci/ might as well be reddit or a YouTube comment section.

Many factors can affect weight loss. Everything from mental issues developing/going away (possibly as a result of exercise and a better lifestyle?). Age related hormonal changes, drug use or drug cessation.

And if I don't take your word for it then, personal bias, water weight, weight loss but no maintenance or not enough time has passed for maintenance to appear. Studies show insane bias when people measure their own caloric intake and weight loss. It's bias that extends beyond someones consciousness and honesty alone.

it's funny that the best argument I have seen against >>10031299 is someone always popping up and saying "hey i did it!". How come ~7500 subjects studied under clinical settings and without the effort to make their own diets or routines and even getting paid for the study(?) have not been able to replicate what you claim to have done so easily. Or do you feel like you are special, and other people are too mentally weak or something?

>> No.10032291
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10032291

>biohacking

>> No.10032525

>>10029685
Le ebig haxxorz

>> No.10032568

>>10032291
This

>> No.10032592

>>10030330
>Because you actually damage the body
He doesn't know about hormesis.

>> No.10032593
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10032593

>>10028065
Here I give you an appropriate rendition of a transhuman.

>> No.10032598

>>10028058
>exercise and diet meme
Calories in, calories out you little piggie

>> No.10032599

>>10028058
Kek, most pathetic cope I've seen in a while, move your ass you disgusting fat fuck.

>> No.10032617

>>10029685
2hr 45m of hacking
4h 15m of social media
1h of dance dance revolution as “exercise”
And shockingly only 1h to split between personal projects and romance

You’d be better off:
1h in gymnasium doing an actual workout
4h 15m reading a nonfiction book of your choosing
2h 45m taking a chick on a date
1h personal project of romantically fucking that chick
6-8h sleeping like a normal human bean

Otherwise 10/10 if it’s bait.
Fuck it, 10/10 if it’s real, you magnificent retard

>> No.10032622

>>10031299
The point of diet and exercise is to not give in to cravings to eat mass amounts of food, your pseudoscience excuses are just that: excuses. Stop being a pig and you’ll lose weight.

>> No.10032644

I've been fasting, exercising, and sleeping properly. Yet I'm still too unmotivated to do anything else.

>> No.10032650

>>10028067
tfw i dieted and exercised and list weight and now am /fit/

makes reading your whiny faggot bullshit a sexually arousing experience

>> No.10032653

>>10032287
yeah basically by measuring a bunch of fat, sad, secret eater retards you’re making me think that im basically a health god thanks please keep sucking my dick

>> No.10032666

>>10029685
08:00 onions and cum cocktail
08:15 chia seeds
08:45 transcendental meditation
11:00 gender research studies
13:00 adaptogenic lunch with probiotic cum cocktail
13:30 self--love affirmations
14:00 current issue research on twitter
16:00 kale snack
16:15 work
17:00 prancercize
19:00 valerian tea with a side of goji berries

how am I doing lads

>> No.10032684

>>10028031
Spend less time figuring out how to dope yourself and more time being productive. Just drink coffee like normal people.

>> No.10032911
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10032911

>>10032622
Calling me fat again to either make me proof that I am not which would make me look ridiculous, ignore it which would make me look suspicious or defend myself which would make me look suspicious and also insecure. It's a lose lose lose situation. That's how ad hominems work. Anyone with some brain would understand that prolonged cardarine and meth use is sufficient to make me as lean and anabolic as i could possibly be.

Let's get to your attack which focused on only one point of my argument.

If you don't give into cravings then your appetite goes up exponentially more. Appetite is not something you can just not follow through with. It will be harder and harder to abstain over time.

And if somehow you do manage to abstain eternally, then you are going to:
1) Significantly reduce your metabolism which will lead to lethargy.
2) Drastically change your hormone profile including a reduction in testosterone
>www.ncbi.nlm.nih.gov/pmc/articles/PMC3569090/
3) You will have a significant increase in cortisol which will cause hypertrophy, neurodegeneration etc...
>www.ncbi.nlm.nih.gov/pmc/articles/PMC2895000/

And great evidence you've put through. Back to /pol/ or whatever board you crawled from. Your hate for weak/leftist or w/e agenda has turned you into the same abomination that lacks basic capabilities for a logical assessment of an argument.


>>10032684
This is my area of study. I am an undergrad physiologist in my final year. I am surprised at the amount of people not interested in pharmacological or other body modification techniques that could considerably improve your functioning or well being yet continue to employ such methods at a superficial and ineffective level ("drinking coffee").

>> No.10032917

>>10032653
Yes fat sad secret eaters cannot control their physiological responses but you can. You just adjust your hormones and metabolism however you like.

You should teach us your ways health god.

>> No.10032928

>>10032911
prove*
hypotrophy*

>> No.10032941
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10032941

>>10032291
>>10032525
>>10032617
>>10032666
>>10029685

Strawmanning this as the popular culture of "biohacking" which is based on little scientific evidence and a lot on edgy transhumanist/futurist fags.

I could've titled this thread anything else but biohacking is the most fitting term. Just because fags use it doesn't mean it doesn't have a niche where it can be taken seriously (pharmacological approaches).

And just because there are a lot of "naturalist", vegans, etc... memers that refer to themselves as biohackers doesn't mean the term can no longer be used to describe more sensible applications.


This thread has so far been filled with logical fallacies. I haven't posted on sci for a while. I wonder how downhill it has gone since I last came on here.

>> No.10032971

>>10032593
nah, thats just retarded. If you could connect the nervous sytem with these wires completely to the system, what do you need the fucking screens for ? And why would you have water standing there when it can just be poured in with an injection ?

>> No.10032987

>>10032971
I guess water is needed in the GI tract for many functions. Injecting it into the blood stream without drinking any at all could lead to damage(?)

>> No.10033079

>>10028031
Spend all that time figuring that shit out, buying supps and eating them on exercise and reading books

>> No.10033097
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10033097

>>10028031
>>10028041
>>>420chan
Fucking junkies.
>>10028058
>Being fat isn't something you can control most of the time.
That's true. The average fat fuck is genuinely unable to stop ximself from stuffing down twinkie after twinkie. That's why you need responsible family and friends to stop you when you're binge eating trash.
>>10029685
It's trash.
>>10030940
"biohacking" is the equivalent of house mom blogs. Just replace ginger shots with some retarded useless drug.
>>10032666
Better than most people in this thread.
Also, checked.
>>10032941
>I wonder how downhill it has gone since I last came on here.
It's already beyond shit and getting worse everyday, particularly because subhumans like you post here, you fucking kike.

>> No.10033102
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10033102

>>10033097
i want to suck on your brain

>> No.10033213

>>10032917
i eat less and work out more

where the fuck does your skinny, weak, out of shape tweaker ass get off on telling me that i didn’t lose 75 lbs at the end of high school and, since then, haven’t gotten into great shape

are you trolling?

>> No.10033295

>>10033097
>/pol/tarding this hard

Yikes

>> No.10033304

>>10032941
Dude, you're IV'ing meth. Everything you say can be disregarded.
>>10033097
Eat shit, /pol/tard

>> No.10033357
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10033357

>>10033304
"Dude" you are administrating a drug in the most efficient way. The drug has social stigma around it and I am unable to prove how it is harmful in any way but I'm gonna use the pre-established social stigma to disregard all your logic. Not one study on low dose (normal light dose with no redosing) has shown the development of tolerance, dependence, or any other harmful effects except the reduction in a persons ability to filter out information. All other effects are positive (neuroprotective and other benefits).

when someone goes from calling you "big guy" to "dude.." you know they are losing confidence in themselves (not sure it's the same person but still making the point)

see >>10032592

>>10032598
>>10032599
None of what I said argues against the laws of thermodynamics. My argument was that calories out become reduced due to metabolism, compensatory behavior. And calories in increase due to substantial and exponential appetite increase. please review the evidence and try to refute it if you want to voice your opinion.

And probably same fagging. I haven't seen so many posts at once all of which are lacking any evidence to support their argument.

>>10033097
see figure in >>10032911 and neck yourself

>>10033213
I've explained the many variables that could affect weight loss (see >>10032287
). I am talking about a fully controlled environment for just exercise and diet. Your anecdotes mean nothing. If it was possible you'd be able to replicate the results or understand why it is possible in some and not others. But so far all the evidence point to factors outside of ones control such as changes in metabolism, hormones (appetite/behaviour).


>Make a thread to discuss pharmacological approaches to modifying your bodies performance.
>end up dealing with /pol/, /fit/ and other brainlets.

>> No.10033369

>>10033357
The optimal human has muscle and cardiovascular capacity. Why do you have neither?

>> No.10033412
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10033412

>>10033304
>>10033357
Wow, that's the first time I've been called a /pol/-tard, presumably by false-flagging genuine /pol/-tards or just straight up middle class zoomers trying to justify their drug abuse to their boomer parents by calling it "biohacking".
In any case, people are laughing at you both online on 4chan and IRL, you pathetic fucks.

>> No.10033435

>stop trying to justify things that oppose my pre-determined socially imposed views

cringe and strawmanning again

>> No.10033485

>>10028031
>meth
You taking regular meth?
Or are you taking 2-FMA?

>> No.10033632

>>10031299
>Fasting
>Get your hormones in appropiate levels

>> No.10033655
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10033655

I am extremely interested in this subject, OP. I haven't done a great deal of research myself, but I have experimented with and am highly fond of nootropics and their potential.

Also, FYI, I've been taking 2600mg of Ashwagandha supplements for the past 4 or 5 weeks in the morning along with 200mg caffeine. I'd be hard pressed to say it has made a great deal of difference, but I used to take 300mg of Buproprion and 20mg of Celexa daily (which was fucking mind-blowingly effective for a few months) and I'd say the caffeine + ashwagandha combo is, at the very least, an effective placebo.

I'm about to try to reinstate prescription amphetamines to my diet. I have way too much routine studying and mental work to do for just caffeine and ashwagandha alone.

Keep up the good work, OP. Naysayers have no fucking idea the long-term benefit of managing an effective biohack regiment.

>> No.10033664
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10033664

>>10033485
I take a daily dose of 10mg meth for about 3 months. No tolerance has developed, I've been able to get off of it with no cravings or withdrawals. It helps me remain goal orientated and focused and awake which helps me in my final year at university. My sleep is improved if anything.


Meta analysis extract in figure. And before anyone comments, yes it does mention uncertainty regarding IV dosing. But IV dosing wont change much and is more bio available. Meth has a long half life so it will remain in the body for long either way. I guess oral would make it more XR and hence more therapeutic but you'd lose ~30% of the drug.
>https://www.ncbi.nlm.nih.gov/pubmed/17694436

Other studies discuss how tolerance doesn't develop meaning dependence doesn't either at such doses.
>study showing reverse tolerance at low intermittent doses of meth(?) really cba reading it now so I can't tell for sure but look into it.
>https://www.jstage.jst.go.jp/article/jphs1951/49/2/49_2_197/_pdf
>I've had previously researched this and I believe it's serotonin dependent and serotonin depletion due to meth only occurs at high euphoric doses.(?)

An old study included children
>imgur.com/a/OLaEtuW

Difference between high and low dose in rats
>i.imgur.com/FN2PJqi.jpg

More on dose dependent effect
>https://www.ncbi.nlm.nih.gov/pubmed/25724762

And believe me I've tried really hard to find a study that shows a negative effect of low dose meth

I'll reply tomorrow with better literature and responses to anything questions or criticism

>>10033655
As I was researching through the meth studies. I found this study which looks are protective compounds to be taken in combination with amphetamines.
https://www.ncbi.nlm.nih.gov/pubmed/8531070

I will address all this again tomorrow properly. Really tired rn

>> No.10033669

>>10028257
https://www.youtube.com/watch?v=0UqxC2RDF64

Interesting

>> No.10034053

>>10033097
Hey anon, go suck some cock.

>> No.10034058

how do i get blonde hair

>> No.10034123

>>10032971
>poured in with an injection
Ha, it has to be isotonic, unless you want the internal soft-bodied organs to swell. Swelling isn't a problem until we look at the brain, which is in-cased in the cranium.
>thats just retarded
Firstly, the proper usage is "that's," and not "thats." Now this is meant to be retro futuristic, nostalgic, and just plain cool. It obliviously lives in a time where screens and wires aren't necessary, but that doesn't mean they aren't functional, and furthermore functionally subjective.
>>10032987
As for you, I guess you've never heard of "dry fasts," and "dry fasting." The gastrointestinal tract doesn't need water, presuming the individual gets it intravenously.

>> No.10034133

>>10034123
Have fun with severe constipation and triggering virulent bacterial behavior. The gastrointestinal tract's mucus production has limitations, and liquid, weight, so forth has definite signalling roles in gut motility.

>> No.10034159

>>10034133
We presume this transhuman is feed intravenously as well and possible even had a gastrointestinal-ectomy.

>> No.10034585

>>10034123
yeah, hence the (?). Not something I've looked into. There are other thoughts though. Things like nutrient absorption and what GI functioning. But it's too much of a topic to think about for a meme image. I guess all these could also be injected or w/e.

>> No.10035317

I've been taking modafinil wHen I need to study, thinking of taking it more regularly about 2-3 times a week or more. I find it quite nice and cheap making me more alert and imo better than caffeine. I would like to use amphetamines but I'm too scared.

>> No.10035350

>>10034058
Eat a lot of honey, lemons and nordic semen

>> No.10035438

>>10032941
Every one of your replies is an essay. Stop doing meth you retard

>> No.10035454

>>10031299
I completely agree that conventional ways of losing weight are bad for obese people but they can always fast. As in not eat for a long period of time (40-50 days depending on their weight). The results are quick and the disadvantages are low. You don't have to be fat if you don't want to.

>> No.10035516

>>10034123
>Ha, it has to be isotonic
so just make it isotonic

>Firstly, the proper usage is "that's," and not "thats.
yeah, im gonna type it like this errytime gives me 1 second more on 4chin which is 1 sec waste more

>Now this is meant to be retro futuristic, nostalgic, and just plain cool.
i get it could have a cool atmosphere for some. For me its more of a dystopian picture.

>> No.10035551

>>10028058
>Being fat isn't something you can control most of the time.

This is an emotionally driven statement. Unless you can prove that MOST of the time fat people are fat because of reasons outside of their control? Of course this would have to be pretty strong, and controversial evidence, given the lack of obesity in countries where food is not in abundance and people's lives are less sedentary.

I am looking forward to your reply.

>> No.10035880

You guys taking meriva/longvida curcumin?

>> No.10036183

Say everything else is somewhat in check, do these nootropics/supplements make a noticeable difference? If so, which nootropics made the biggest difference and in which ways did you notice the change?

>> No.10036218

Oh God you idiots. This isn't biohacking, it's just taking expensive drugs you retards.
Make your eyes able to see in the dark, implant actuators healing dead muscles, regain eyesight by nerve redirection and training. That's biohacking.

>> No.10036223

>>10036218
What youre talking about is advanced biohacking. This right here is biohacking as well and you better take advantage of it.

>> No.10036244

>>10036223
It's a scheme to squeeze money out of you. That's all it is.

>> No.10036589

>>10035880
I don't think there is enough to support curcumin. I haven't done much research on it though.

>>10036244
You are somewhat right. Yes there are hundreds of meme supplements/nootropics out there. But drugs can do almost everything in your body. And in some instances those actions can seriously improve your functioning.

Things like GW501516, meth, melatonin can seriously help you (the latter two depend on your sleep quality and your ability to concentrate and whether either is impaired).

>> No.10036894

>>10036589
What are your top 5 for improving focus, concentration etc.?

>> No.10036908

>>10028048
This
Evolution has been working on this whole "make the body work" a hell of a lot longer than us, obey your body and its constraints.

Think about it. There's still active research around normal human metabolism, which means we sure as hell don't know the myriad metabolic changes around "muh daily regiments"

>> No.10036922

>>10028067
>>I have only been able to find one study which may hold some promise for weight loss using exercise and diet only.

Have you tried LOOKING WITH YOUR EYES? Jesus Christ. The reason the doctor keeps telling you to exercise more and eat less is because it fucking works. Even the ancient Greeks understood that fitness and fat loss were causally linked.

Fat brainlets off this board and go to the gym, walking to and from the fridge isn't exercise

>> No.10037008

>>10036908
Tard OP wants us to believe IVing meth is a good idea.

>> No.10037544

PRL-8-53 is a very interesting substance in the nootropic category. It is supposed to help with short term memory and recollection. From what I read it works and isn't just placebo. Maybe worth looking into.

>> No.10037623
File: 14 KB, 1124x121, b727f93510b05b21cfdd19658b31160c.png [View same] [iqdb] [saucenao] [google]
10037623

>>10037008
Another brainlet can't make his point but wants to state his socially imposed opinion

>>10036894
I have autism and ADHD. For focus nothing has been superior to meth. It is the holy grail of amphetamines.

>inb4 adhd denial. See >>/sci/thread/S9900417


You avoid all peripheral sides due to better pharmacodynamics (which usually cause sensory overstimulating due to my autism) and it has the longest action and is very tolerable and even nootropic at a single dose as early as possible in the day between 2.5-30mg. The dosage depends on how you metabolize it/tolerate it.

If I had to guess, I'd say:

1- Meth for attention/concentration and other potential improvements like mood stabilization. This is very dependent on your brain functionality or pathology. Some people might feel nothing but anxiety and disturbances from it. But I think anyone would benefit from the much lower doses if that's a concern (2.5-5mg)

2-nAChR agonists(?) see figure but do your own research

3-Antidepressants if you have depression and if they are going to treat that depression(?)

4-memantine(?) if you dig deep enough you might find some non heavily established concerns

5-racetams, nootropics, >>10037544, and a other nootropics that don't have much evidence
>>10036922
see
>>10031299
>>10032911

Then comeback and call me names

>> No.10037730

itt autistic fatass taking meth tells you exercise and diet dont work

>> No.10038076

Anyone taking rapamycin?
How'd you get a script for it?

>> No.10038744

>>10035454
I've explained how fasting completely changes your horomanal profile leading to health risks (cortisol release), appetite exponentially increasing (to try and compensate 3 times over and increasing for the calories you miss and if you abstain) and compensatory behavior. And I explained how even an ubermensch who can monk through it by some>>10036908

Please consider reading my posts

>>10038076
Sounds promising at low non frequent dosage (have read almost nothing about it so dont take my word for it). You're best bet would be online pharmacies like "inhouse pharmacy". You'd have to check the reputation yourself though and make sure the product you get is real. Especially for things people don't usually order.

>>10037730
>>10036922
>>10035551
>>10035438
>>10033412
>>10033213
>>10033097
>>10032653
>>10032650
>>10032622
>>10032599
>>10032598
>>10031518
>>10031183
>>10028048
Probably 2-3 samefaggers collectively in all of their posting providing 0 evidence or argument to back up their points. Thanks for keeping my thread alive.

>> No.10038749

>>10036908

Accidently replied in my last comment but had no space. See this:

You are right. Many years of evolution have prepared us for the most optimal functioning. However the exponential rise in technological advancement has placed us an unfamiliar environment for the first time in millions of years of evolution. All the urges we have that we act upon to develop our body physically and mentally are now out of the equation. We have bypassed all the mechanisms that lead to our development.

1. Food - supermarket vs hunting
2. Safety - organized law enforcement and tech to help us feel safe without the need to be alarmed and prepared
3. Procreation - porn, condoms ability to fuck more often without needing being burdened by kids, sexual liberation, drugs that increase promiscuity, etc...
4. Socially imposed belief that intelligence and fair treatment is good for society. This leads people to remain abusive of the inferior class due to our primitive behavior but in more indirect and psychologically destructive ways over the good old hit him in the head with a rock.

In this society we can let evolution take care of us and go out with a different or extinct society. But if you value your individual well being then you gotta try and cope as best as you can.

>>10036183

Most people that take nootropics have some sort of issues. When you go online and look at anecdotes you will always find an exaggerated report by someone who specifically benefited from it.

Imo, it all depends on your pathology and your genetics. How do you metabolize the drug, will the drug fix something that's broken? It's like using an asthma inhaler when your lungs aren't inflamed. The effect won't be anywhere near as pronounced. Now overall a lot of nootropics are shilled and useless. But some stuff have more pronounced effects and can be exploited in different ways depending on your needs. I say you just go through the thread and see what people say.

>> No.10038762
File: 149 KB, 769x1280, memes.jpg [View same] [iqdb] [saucenao] [google]
10038762

>>10035317
Modafinil is good. I prefer meth like I've stressed many times. But modafinil is a lot more safe to aquire and be sure of.

If you are taking modafinil I suggest you take it only as early as possible and stick to lower more sustainable doses. 50mg and 100mg if need be. I also suggest you cycle it. Meaning you choose a few days of the week when you think you will need it most. And on other days just drink coffee to prevent tolerance.

Maybe something like if we assume you have a normal wagie/student week:

Mon - Coffee (feeling fresh no need for excess)
Tue - modafinil 50-100mg
Wed - modafinil 50-100mg
Thu - modafinil 50-100mg
Fri - 500-800mg phenibut + Coffee
Sat - nothing/cbd oil
Sun - nothing/cbd oil

I also suggest you try armodafinil and see which one works best for you. Some find that armodafinil is a lot more sustainable

>> No.10038780

Routine:

Supplementation:
depression, autism, anti-inflammation
Vitamin D3
Omega 3s
Vitamin C
Magnesium
Probiotics
Zinc

Methylation:
DNA production, general health, longevity, eyesight and organ function
Hydroxy B-12
Vitamin B6
L-Methylfolate
Acetyl L-Carnitine
N-Acetyl-Cysteine
Manganese
Phosphatidylserine

Drugs:
Mental and physical health.
Testosterone 150mg-300mg. Twice a week, 8 week cycle, PCT 2 weeks after last pin, 50/50/50/50 clomid 20/20/10/10/10/10 nolva.
Adderall 20mg. Daily.
Modafinil 50mg. Daily.
Ketamin 100mg. Every six months or so.
LSD 200ug. Every 4-6 months.

>> No.10038844

>>10038780
Not sure about omega 3. A large Cochrane review has posed some questions regarding their effects. But the study has received some criticism.

Any personally observed benefits or (strong) evidence for most the vitamins in the methylation category. especially in relevance to autism.

Drug schedule is good except test imo.

I know it's a great short and low dose cycle but I just don't see the point of it in the long term. GW501516 is enough for me in terms of physical performance. In terms of increasing test I think trying to elevate natural levels is always better than replacing.

The drugs are all non frequent/low dose. Something many people never take into account. Sustainable stack imo. Maybe moda not daily although I'm not sure if tolerance develops at 50mg but I would assume so.

>> No.10038993

>>10036223
>Implying drugs are sustainable focus
The moment you develop a tolerance you're done.

>> No.10039012

>>10028058
>>10028067
>>10031299
>>10032287
>>10032911
>>10033357
>>10038744
Post body, NOW.

>> No.10039024

>>10038762
thanks for the info, i started on 100mg but then moved to 200mg, i also made sure to cycle it when i knew i would be consuming it multiple times a week due to the half life of modafinil. I'll take your suggestion into account and slowly move back with your schedule.

As I am located in Australia i'll have a look into phenibut and cbd oil and see how easy it is to acquire both.

I currently have a large supply of modafinil and i'll check out armodafinil on my next order.

>> No.10039031

Vitamin b-12
Zinc Orotate
Nicotine snus or gum
Ashwaganda
Creatine

>> No.10039210

>>10039012
This

>> No.10039701
File: 2.02 MB, 3116x3869, memesonwheels.jpg [View same] [iqdb] [saucenao] [google]
10039701

>>10039012

All brainlets out of my thread, NOW.

>inb4 /fit/ homoerotic criticism of my features

>> No.10039706

>>10030935

Just tried putting some cbd oil in ejuice and it works really well. No need to buy custom juices IMO but you can.

>> No.10039715

here's my routine

>wake up
>magnesium, multivitamin
>adderall
>some more adderall throughout the day
>melatonin
>sleep

biohacking is just another fancy term for supplements industry the two terms are practically interchangeable

>> No.10039734

>>10039715
>biohacking is just another fancy term for supplements industry
Though I don't use the word internally or otherwise, I disagree. Biohacking is just what it says, finding means to shift into and maintain certain states apart from one's normal range / clustering. Some of the people and places I've been, especially using substances that work "with you" affording you to choose to function in a different way, in a different range, tells me there valid reason for a word like that to exist.

>> No.10039735
File: 45 KB, 600x849, Me, just a hero for fun!.jpg [View same] [iqdb] [saucenao] [google]
10039735

Hi guys, I'm just a hero for fun, and profit. This is my routine for ultimate biohacking:
>100 push-ups
>100 sit-ups
>100 squats
>and top it off with some 10km running.
>EVERY SINGLE DAY!!!
>365 DAYS A YEAR
Got that guys?
Oh, it seems i got a call from the association to fight some lame alien invasors again...
See ya!

>> No.10039747

>>10039701
u have an ugly body

>> No.10039751
File: 7 KB, 179x282, grahahhahrhrhiiiiiiiiiiiiiiiiiiiiiiiiii.jpg [View same] [iqdb] [saucenao] [google]
10039751

>>10033664
>ive been taking meth continuously for 3 months
>i can stop at any time guys trust me im not addicted it helps my mind

>> No.10039758

>>10039701
>this guy is giving you health and fitness advice that contradicts all previous knowledge and understanding
>he is also a meth head

>> No.10039763

>>10039701
Looks like the methheads that attempted college

>> No.10039773

>>10028031
Can any medfags tell me if it's safe to start using random supplements while I already have medication? I take 36mg of Concerta each morning, 75mg of Effexor at night, and 3mg of Risperdal, 1.5 in the morning and 1.5 at night.

>> No.10039794

>>10039773
how the fuck did you end up with that drug cocktail lmao that's nutty

quick observation:
you can't take any supplements that boost serotonin because of your antidepressant

>> No.10039807

>>10039794
This is the medication my psychiatrist prescribed me. Are these medications even good? One of them is supposed to help my focus and I'm always lazy and never want to focus.

>> No.10039811

>>10039773
It is not safe. You have a kind of bizarre mix going there anyway. Can you say a bit about what they're treating?

>> No.10039819

>>10039807
This is my unprofessional opinion as an internet shitposter.

>Concerta
This is the good drug you have. I take Adderall myself but methylphenidate is supposed to be the safer ADHD stimulant.

>Effexor
>Risperdal
Seems like your psychiatrist likes to throw random shit and see what sticks. There's a chance these two drugs interact in a negative way. From my personal experiences watching people these types of psychiatric drugs slowly make people dumber and more insane.

>> No.10039828

>>10039811
The Effexor is to treat my depression, I'm diagnosed with major depression. I also struggle with anxiety and anger issues, and ADHD. I'll be honest I've been feeling strange for a while. I've been having mood swings and I don't feel right. I had this thing a while back where my hearing would go in and out and I felt dizzy.

>>10039819
My psychiatrist is some Indian dude than can barely speak English. I'm really getting anxious from this now.

>> No.10039832

>>10039828
Get a second opinion from a better psychiatrist. You have a choice here, might as well see if you can get a more qualified person to treat you.

>> No.10039840

>>10039832
I'm a minor, so, I don't have a giant say in the matter. I brought up the concern to my mom and she got angry at me and told me he knows more than me and he knows what he's doing. Meme.

>> No.10039844

>>10039828
Honestly, with no undue bluntness I'll tell you my own opinion is that orthodox medicine has nothing for you, or most people for that matter. Your issues have deeper causes, and could relate to diet and lifestyle. Also electromagnetic fields, even though it very well established, it's been made a taboo and people don't think it's not real because no one acts like it's real.

I'd look for other answers. These people are nothing but hacks, quacks, and glorified witch doctors that sit there with that bored look on their face and stare at you like you're the current damaged thing that brought itself into the office. Part of that is probably also because they're well aware their methods are crude and not worth shit half the time, but have a comfy salary, lots of bills, and major sunk costs.

Don't think I'm someone without problems just saying this to you either. I mean it. Risperdal is an broad spectrum receptor antagonist, and primarily an antipsychotic. They wanted to give me an SSRI for nerve pain. That's what these people do.

>> No.10039848

>>10039844
>Also electromagnetic fields, even though it very well established, it's been made a taboo and people don't think it's not real because no one acts like it's real.
I'm tired. this sentence came through garbled but I think the meaning is clear.

>> No.10039849

>>10039840
You're in a tough spot, I feel for you. You can't abruptly discontinue your antidepressant OR your antipsychotic because the withdrawals alone cause adverse effects. If you've been taking both for a long time you're kinda screwed here.

>> No.10039852

>>10039849
I've already felt some of the side effects of abruptly stopping. My mom fucking wouldn't get my prescription for me because she was too lazy, and I couldn't go get it or I would, and I was off of it for two days and I had horrible panic attacks and depression and thought about suicide quite a bit.

>> No.10039856

>>10039852
Just to note, I'm not entirely sure it was caused inherently by me not taking the medication, it was only 2 days, but I don't know much about medication as I said.

>> No.10039857

>>10039852
That sounds a lot like negligence what the fuck

>> No.10039859

>>10039857
She's an idiot, as much as I hate to say that about my own mom. She wasn't ready to have a child and she only did for religious reasons. It sucks but whatever, cant change what I was given.

>> No.10039877

>>10039859
Dunno what to say faam. I've always had pretty good luck with psychiatry because capitalism meant options.

>shopped around psychiatrists until I found a pill doctor that was happy to give me a shitload of Adderall for the ADHD I probably actually have

It's silly. If you don't like a doctor and their treatment you can take your money straight to another one.

>> No.10039935

>>10039747
>>10039751
>>10039758
>>10039763
ABORT FAT MEME

And I look exactly the same before and after meth

>inb4 post before and after pic

Brainlets desperate. Seems like you still don't want to leave. Thanks for keeping the thread alive.


>>10039773
A lot of drugs are versatile and have little interactions with such psychiatric meds. I'll read through and make suggestions when I have more time. If you are interested in anything then let me know. I'll tell you if it's risky or not.

>> No.10039987

>>10028031
I fap like 5 times a day, does that count?

>> No.10040382

>>10039935
Congrats you're only skinny-fat well done. /fit/ btfo by a skinny-fat tweaker

>> No.10040711

>>10040382
Turning this into a /fit/ thread. People have natural limits to the amount of muscle to fat ratio they can have. /fit/ is largely unaware of that and all /fit/heads think they can achieve steroids tier or are on steroids.

I have a very healthy HR, high endurance (11.5 bleep test, and I don't need to compensate with turning my life into lifting. I have more important things to achieve especially in academia.

Point being, I could've been fat, skinny, built and it would have had nothing to do with this thread. You are trying to attack me personally because things didn't go your way. Sad, but again, thanks for keeping the thread alive.

>> No.10042153
File: 468 KB, 2560x1920, 27525_battle_angel_alita.jpg [View same] [iqdb] [saucenao] [google]
10042153

>>10028031
Some stuff in the /cyb/ FAQ:
ftp://50.31.112.231/pub/Alt_Cyberpunk_FAQ_V5_preview20.htm

>> No.10043445

>>10028031
lmao if people think biohacking is a meme they can turn in their "IQ above room temp" cards because that's just plain stupidity

>> No.10043450

It sounds reasonable, I mean it’s not like you’re doing anything dangerou-
>My routine:
>Meth - 10-15mg IV daily

>> No.10043473

It feels like any sort of basic substance can't do shit unless as medicine against ails of civilization, regular disease or disease of aging. If it was so easy evolution would already have incorporated the effect naturally. Of course, improvements are possible, but they'll be hard won.

>> No.10043490

>>10043473
Google ethnopharmacology, and do some reading on phytochemistry. carvacrol, thymol, lupeol, and eugenol will wipe out a broad array of infections, but your body would have never have cause or means to manufacture it. Instead it just sends little machines around to engulf and bombard agents it can identify as foreign with superoxide and hydrogen peroxide. A comparatively simple action with collateral damage, but it doesn't risk excitotoxicity and waste of resources. All the above compounds readily pass the BBB, and if you look at most higher organisms, they have a definite bias against synthesizing strongly psychoactive compounds from afar.

The brain is like the logic employed by a single cell's intra and extra structural machinery, or a small population of cells (which are coupled oscillators). If it knows, and has the consciousness to assess some aspect of its state, it has the ability to seek out and introduce these stronger compounds to alter itself. Same logic, different mechanics and scale.

>> No.10043576

>>10043450
I can definitely see an arresting officer and judge taking his experiment into consideration.

>> No.10043753

>>10028048
how fucking boring would it be if humanity managed to get to it's ideal state of biology through evolution, rather than it's own design? how fucking humiliating is it to believe the best you can be is the culmination of random interactions, that you personally deem to be more significant than yourself?

>> No.10044008

>>10043490
That's medicine, possibly also a civilization-induced deficit. I mean things that push you beyond your peak in a sustainable manner. Take roids, you get huge as fuck but it impacts your health in the long run.

>> No.10044016

>>10044008
>I mean things that push you beyond your peak in a sustainable manner.
You're going to be looking at herbs then.

Constituents are antioxidants, acetylcholinesterase inhibitors, calcium channel blockers, so on.

>> No.10044025

>>10044016
Our ancestors probably ate herbs by the fistful
Like I'm not saying chemical augmentation is hopeless, I'm looking into TRT myself, but it's less biohacking and at best chemical primitivism. All the real transhuman shit is a few decades away.

>> No.10044053

>>10044025
Well, blame the machine I guess, that has disallowed the broader population from even entertaining the idea that low intensity non-ionization radiation can affect bodily processes.

You ever watch Serial Experiments Lain? The drug in the second episode, "accela", is not strictly science fiction. That show, and the 90's / early 2000's pseudo-60's spirituality and consciousness movement that inspired it, rooted in computers and the emerging internet, was actually hitting on something quite real. With the crystals and "energy" and resonance, and so forth.

There's a good paper about this specifically that I'll try to find.

Back in the day fields like the above were used for medical treatments, and do have real therapeutic value when used correctly and used specifically. Ignoring microwave diathermy, the most famous application was use of pulsed fields to augment fracture healing, especially non-union fractures. Before that, short waves were used to treat various diseases, including bipolar, "hysteria", and schizophrenia, as well as high blood pressure and malaise. The person would be put in a condenser field generally for a period of a few minutes, then it was over. This method would cure certain types of schizophrenia for a period of 2 weeks or so. If the power density was wrong, it would make it worse.

Modulation of brain function has been the best documented. eg Bawin et al reported a 56uT 1Hz magnetic field generated via helmholtz coil, completely eliminated rhythmic slow activity (theta rhythm) in hippocampal slices. Bawin and Adey of course demonstrated prior the 40% increase in Ca2+ efflux when exposed to VHF fields amplitude modulated at 16Hz. Later replicated by Blackman et al.

>> No.10044056

>>10044053
Lol are you the meth poster
Makes sense I guess

>> No.10044064

>>10044053
Here are the papers I mentioned.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644491/

https://www.ncbi.nlm.nih.gov/pubmed/8915548

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC393172/

>> No.10044068

>>10044056
Meth poster?

And yes, our ancestors used herbs frequently.

>> No.10044081

>>10044056
And let me guess, ya ain even gonna read it. You people are boring. It's like being the only real person in a sea of NPCs.

>> No.10044501

>>10028031
Do you even feel that meth?

>> No.10044505

>>10038993
Done would be nice.

Worse than before is usual stuff.

>> No.10044507

>>10039735
Jesus

>> No.10044518

>>10044064
Bass music over wifi?

Causing stress?

How much of that stress is damage causing?