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>> No.7604153 [View]
File: 270 KB, 647x721, Alzheimer CpG.png [View same] [iqdb] [saucenao] [google]
7604153

>>7604084
Also, any gene being expressed in the brain is only expressed as a product of epigenetics. Since every cell has to undergo particular epigenetic modulations during (for example) cell division; such as histone acetylation to allow transcription factors to access a gene.

Since a cell HAS to undergo chromosomal condensation during cell divison (and makes use of histones to do so); every gene is influenced by histone interactions, and so every gene is influenced by epigenetics by default.

The only issue here is differences in epigenetics between individuals and the effects it has on a phenotype.

But if you look at pic related. A tiny number of CpG methylation sites (71) correlate with Alzheimer severity out of more than 415 thousand. It's not unreasonable to extrapolate that dysfunctional epigenetics can lead to similar mental disabilities (and potentially above average mental abilities), since there are so many sites for CpG methylation. Without taking into account the several other epigenetic mechanisms

>> No.7598252 [View]
File: 270 KB, 647x721, Alzheimer CpG.png [View same] [iqdb] [saucenao] [google]
7598252

>>7598238
Yes

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