/sci/ - Science & Math

>>11348986
The reason you're not converting CBD to THC is?

>>11294504

>distilling

Just water. Heat kills LSA.

>concentrating

Evap Acetone on large flat glass pyrex pan for maximum surface area. Once dry, add a smaller amount of Acetone to pick up alkaloids, evap on smaller flat glass pan. Add Acetone again, smallest amount possible to pick up all the alkaloids. Evap in tiny glass vial. Once dry, tartaric acid and water. Shake and swish until you get as many alkaloids in solution as possible. Verify progress by occasionally checking florescence under blacklight. Filter once and done.

>extracting

Acetone tek in thread. Don't fuck with naptha NP wash, everclear extract shit it has a terrible yield. You want a polar aprotic solvent so there is no hydrogen available for bonding. The toxins in the seeds are thought to be non-polar and/or cyanogenic glycosides as a lot of morning glory sickness symptoms align with acute cyanide poisoning. Water is commonly used, but it's a polar solvent that has a hydrogen available for bonding so it still breaks down toxins slowly. I think LSA is slightly more basic than water so water acts as a mild acid to LSA. Keeping water cold helps reduce acidity and lower toxins entering solution which is why it kinda works but only reduces nausea it doesn't eliminate it. Garlic added to cold water extracts works to neutralize cyanogenic glycoside toxin build up in the body by providing thiosulfate sulfurtransferase enzymes in your body extra sulfur to convert more cyanide to less toxic thiocyanate in vivo.

>hydrolysis

Of an amide? Supposedly potassium hydroxide in a suitable solvent could convert LSA to lysergic acid. Then it's pretty complicated from there. What would you use for the diethyl moiety and how would you acquire it? DEET bug spray? Column chromatography is usually a big barrier. How would you go about testing purity?