/sci/ - Science & Math

Sweetened Drinks Are Linked to Chronic Liver Disease And Liver Cancer

It is widely known that consuming sweetened drinks can contribute to obesity and insulin resistance. A recent prospective cohort study published in the Journal of the American Medical Association (JAMA) has further revealed detrimental health effects linked to sweetened drinks, particularly concerning liver disease.

https://jamanetwork.com/journals/jama/article-abstract/2807987

>Results
>During a median follow-up of 20.9 years, 207 women developed liver cancer and 148 died from chronic liver disease. At baseline, 6.8% of women consumed 1 or more sugar-sweetened beverage servings per day, and 13.1% consumed 1 or more artificially sweetened beverage servings per day at 3-year follow-up. Compared with intake of 3 or fewer servings of sugar-sweetened beverages per month, those who consumed 1 or more servings per day had a significantly higher risk of liver cancer (18.0 vs 10.3 per 100000 person-years [P value for trend=.02]; adjusted HR, 1.85 [95% CI, 1.16-2.96]; P=.01) and chronic liver disease mortality (17.7 vs 7.1 per 100000 person-years [P value for trend<.001]; adjusted HR, 1.68 [95% CI, 1.03-2.75]; P=.04). Compared with intake of 3 or fewer artificially sweetened beverages per month, individuals who consumed 1 or more artificially sweetened beverages per day did not have significantly increased incidence of liver cancer (11.8 vs 10.2 per 100000 person-years [P value for trend=.70]; adjusted HR, 1.17 [95% CI, 0.70-1.94]; P=.55) or chronic liver disease mortality (7.1 vs 5.3 per 100000 person-years [P value for trend=.32]; adjusted HR, 0.95 [95% CI, 0.49-1.84]; P=.88).