/sci/ - Science & Math

Set my own hand on fire with ethanol more than once while replating bacteria. That glorious moment when you go all "Ok, appears my glove is burning ..." and just stare at it in amazement for a few seconds straight until your pain receptors kick in. Gets you every time.

>>15357389

>Wut?

Faulty and/or accidental integration into the genome being one reason. Our genetic code is full of fucking transposable elements, HERVs, most of the narrowly suppressed and ready to copy/paste whatever shit you feed into the cell in random positions all over your chromosomes. Introducing foreign genetic material into a cell, especially when done at high dosage or with artificially increased half life is a very silly thing to do.

>>15257680

>What precisely is the difference, and how does it differ from e.g. mitosis?

A virus cannot establish its own "metabolic gradient", might sound trivial but it is not ... they are incapable of producing the energy required for replication, so they need to hijack a cell which does produce said energy.

>>15163559

Was an entirely different case. These "lab rats" did test positive for antibodies against HIV ... as that particular "vaccine" was some kind of fusion protein between the viral spike and some other protein derived from the HI virus. It was actually terminally retarded if anyone did assume that this would NOT cause antibodies against HIV protein to be produced ... oh what a surprise!! Fucking braindead morons.

>>15133625

Yes. A slight tan aside I do however not look like a nigger. :)

>>15114175

Must not even be. Could as well be an autoimmune reaction triggered under certain conditions by the combination of the spike antigen, adjuvant (meaning the LNP particles and mRNA itself) as well as perhaps dead cells from the site of delivery (intramuscular, with the heart still being muscle tissue too).

>>15050057

>i could imagine it can be autoimmune response to spike protein

Not alone ... we got several candidates here and they might work in synergy here so to speak: heavy overexpression of the protein, possible reactive sites in the protein (especially if it is processed into or transcribed as fragments in certain cases), immunomodulatory effects of the LNP constituents themselves, intracellular signaling and downstream effects due to high artificial mRNA load, potential reactions to free mRNA due to degraded LNP particles ... in combination this could have all kinds of silly effects on the immune activation cascade, both in the innate and adaptive department. Might even be "just" simple cross activation due to exceptionally strong stimulatory signals which then override the self tolerance balance for certain human epitopes ... srsly, could go on and on here on what might have gone wrong.

>>14982632

Host/pathogen equilibrium after loss of the unstable gain-of-function.

>>14973197

>when will we start seeing gene editing

Not within the next three decades.

>>14973331

>CRISPR

Heh, good luck getting reliable results outside cell culture with this.

>>14973202

>ultra rich

Retards with lotsa money. Rest is snake oil salesmanship. Should just stick with selling them quicksilver as "immortality cure", here the results are at least well established. ;)

>>14966814

Originally an old established lab tool to introduce genetic material into cells in a petri dish. Rather reliable there aside from usually killing off half your culture due to cellular stress (which you don't really give a fuck about in that case). Otherwise, see >>14966895, dead end technology in Humanmedizin.