/sci/ - Science & Math

>>11323912
No real evidence against it at all, evidence for it comes from some limited studies and many anecdotes, which doesn't mean it is false. Do you need a double blinded RCT to see if jumping off a cliff is good for you? No just use your brain. Evidence to begin a proper clinical trial into the benefits of nofap would have to start from accumulation of clinical experience on the benefits of nofap, that will take perhaps another 10 years when the current generation of medical students become physicians who grew up with the idea of nofap.
For the mean time, you can still speculate and come up with pretty solid biochemistry and endocrinological reasoning for the benefits of nofap.

Constant ejaculation lowers the amount of dopamine that enters your anterior pituitary gland so it stops inhibiting prolactin production. Prolactin then rises, which inhibits GnRH in the hypothalamus. GnRH controls LH and FSH. LH is responsible for the regulation of testosterone in your Leydig cells in your testes. Therefore, it is theoretically possible that the rise in prolactin post-ejaculation (which has been documented) may contribute to depressive effects on the hypothalamic-pituitary-gonadal axis downsteam. See pic-related.

>>11303183
By abstaining from ejaculation (sex included) your prolactin goes down, increasing GnRH from your hypothalamus, that then leads to more LH from your pituitary which results in greater testosterone
The feedback of lower prolactin being released and the more dopamine is used to inhibit prolactin production likely produces the improved "energy" feeling that one gets when on nofap for extended periods of time.
This shit isn't magic, it's rooted in solid endocrinology and neurology, the reason doctors don't talk about it is because this stuff only matters for people who are in a position to practice semen retention (i.e. young men who do not really get sick and so do not matter to doctors), and it's more of a min-max thing to improve the life of the young male.