/sci/ - Science & Math

since I work with anopheles, I'll include a relevant example with a western blot
https://www.pnas.org/doi/pdf/10.1073/pnas.1917042117

figure 1 C; shows a protein stain and a ladder to the left and the western blot of the protein of interest before and after the knockout protocol. In this case, it's showing mosquito innate immunity instead of human blood stains, but the point remains the same. LacZ is the control with an infected mosquito showing AgP47Rec (the protein plasmodium interacts with) is within the midgut, while the RNAi knockdown of that proteins shows no more protein is being made.
This is my job. I make the tools to do these sorts of knockdowns. By removing or modifying that mosquito protein, you could possibly make them immune to malaria.