/sci/ - Science & Math

>antiparkinson effects of fluvoxamine
https://pubmed.ncbi.nlm.nih.gov/32273939/
https://pubmed.ncbi.nlm.nih.gov/27338206/
>anti Alzheimer's effects of fluvoxamine
https://www.neurologylive.com/view/sigma1-agonists-offer-combination-approach-to-dementia-symptoms
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819237/
>general cognition enhancing effects of fluvoxamine
https://pubmed.ncbi.nlm.nih.gov/20373470/
>sigma-1 agonists raise acetylcholine in the frontal lobes and hippocampus but not the striatum and reverse memory impairment from muscarinic blockade
https://pubmed.ncbi.nlm.nih.gov/20060423/
>fluvoxamine dopamine in the frontal lobes
https://pubmed.ncbi.nlm.nih.gov/21487652/
>prazosin (a1 adrenergic antagonist) prevents memory deterioration in Alzheimer's
https://pubmed.ncbi.nlm.nih.gov/23063647/
>a1 blocker reduces risk of parkinson's
https://medicine.uiowa.edu/content/prostate-drug-associated-lower-risk-parkinsons-disease
>5ht1a agonism increases dopamine and acetylcholine in the PFC
https://www.sciencedirect.com/science/article/abs/pii/S0166432808002933?via%3Dihub
>5ht1a agonism raises striatal dopamine
https://pubmed.ncbi.nlm.nih.gov/15906386/
>cognitive benefits of a2c adrenergic antagonism
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558054/
>weed removes alzheimer's plaques
https://www.salk.edu/news-release/cannabinoids-remove-plaque-forming-alzheimers-proteins-from-brain-cells

>>14742571
>antiparkinson effects of fluvoxamine
https://pubmed.ncbi.nlm.nih.gov/32273939/
https://pubmed.ncbi.nlm.nih.gov/27338206/
>anti Alzheimer's effects of fluvoxamine
https://www.neurologylive.com/view/sigma1-agonists-offer-combination-approach-to-dementia-symptoms
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819237/
>general cognition enhancing effects of fluvoxamine
https://pubmed.ncbi.nlm.nih.gov/20373470/
>sigma-1 agonists raise acetylcholine in the frontal lobes and hippocampus but not the striatum and reverse memory impairment from muscarinic blockade
https://pubmed.ncbi.nlm.nih.gov/20060423/
>fluvoxamine dopamine in the frontal lobes
https://pubmed.ncbi.nlm.nih.gov/21487652/
>prazosin (a1 adrenergic antagonist) prevents memory deterioration in Alzheimer's
https://pubmed.ncbi.nlm.nih.gov/23063647/
>a1 blocker reduces risk of parkinson's
https://medicine.uiowa.edu/content/prostate-drug-associated-lower-risk-parkinsons-disease
>5ht1a agonism increases dopamine and acetylcholine in the PFC
https://www.sciencedirect.com/science/article/abs/pii/S0166432808002933?via%3Dihub
>5ht1a agonism raises striatal dopamine
https://pubmed.ncbi.nlm.nih.gov/15906386/
>cognitive benefits of a2c adrenergic antagonism
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558054/

Fluvoxamine, brexpiprazole, atomoxetine, nicotine, cannabis
>antiparkinson effects of fluvoxamine
https://pubmed.ncbi.nlm.nih.gov/32273939/
https://pubmed.ncbi.nlm.nih.gov/27338206/
>anti Alzheimer's effects of fluvoxamine
https://www.neurologylive.com/view/sigma1-agonists-offer-combination-approach-to-dementia-symptoms
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819237/
>general cognition enhancing effects of fluvoxamine
https://pubmed.ncbi.nlm.nih.gov/20373470/
>sigma-1 agonists raise acetylcholine in the frontal lobes and hippocampus but not the striatum and reverse memory impairment from muscarinic blockade
https://pubmed.ncbi.nlm.nih.gov/20060423/
>fluvoxamine dopamine in the frontal lobes
https://pubmed.ncbi.nlm.nih.gov/21487652/
>prazosin (a1 adrenergic antagonist) prevents memory deterioration in Alzheimer's
https://pubmed.ncbi.nlm.nih.gov/23063647/
>a1 blocker reduces risk of parkinson's
https://medicine.uiowa.edu/content/prostate-drug-associated-lower-risk-parkinsons-disease
>5ht1a agonism increases dopamine and acetylcholine in the PFC
https://www.sciencedirect.com/science/article/abs/pii/S0166432808002933?via%3Dihub
>5ht1a agonism raises striatal dopamine
https://pubmed.ncbi.nlm.nih.gov/15906386/
>cognitive benefits of a2c adrenergic antagonism
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558054/
>procognitive effects of atomoxetine
https://pubmed.ncbi.nlm.nih.gov/16231039/

>>14629186
>prazosin (a1 adrenergic antagonist) prevents memory deterioration in Alzheimer's
https://pubmed.ncbi.nlm.nih.gov/23063647/
>a1 blocker reduces risk of parkinson's
https://medicine.uiowa.edu/content/prostate-drug-associated-lower-risk-parkinsons-disease
>5ht1a agonism increases dopamine and acetylcholine in the PFC
https://www.sciencedirect.com/science/article/abs/pii/S0166432808002933?via%3Dihub
>5ht1a agonism raises striatal dopamine
https://pubmed.ncbi.nlm.nih.gov/15906386/
>cognitive benefits of a2c adrenergic antagonism
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558054/
kys filthy dumbass. schizophrenia is associated with HUGE cognition impairments so the newer antipsychotics are designed to improve cognition.

>>14612941
yes.

>prazosin (a1 adrenergic antagonist) prevents memory deterioration in Alzheimer's
https://pubmed.ncbi.nlm.nih.gov/23063647/
>a1 blocker reduces risk of parkinson's
https://medicine.uiowa.edu/content/prostate-drug-associated-lower-risk-parkinsons-disease
>5ht1a agonism increases dopamine and acetylcholine in the PFC
https://www.sciencedirect.com/science/article/abs/pii/S0166432808002933?via%3Dihub
>5ht1a agonism raises striatal dopamine
https://pubmed.ncbi.nlm.nih.gov/15906386/
>cognitive benefits of a2c adrenergic antagonism
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558054/

>>14593683
enjoy your liver damage.
get a real antipsychotic

My stack is
400mg luvox (sigma-1 agonist)
50mg atomoxetine (norepinephrine uptake inhibitor)
4mg brexpiprazole (pic related)
shiraz red wine
weed and tobacco (smoked)

>300mg luvox
>4mg brexpiprazole
>high dose ritalin
>cannabis (smoked)
>4mg nicotine gums

>>14502988
yes 4mg is the maximum dose

>>14489051
Brexpiprazole
>5ht1a agonist (increases hippocampal neurogenesis)
>a2c adrenergic antagonism improves cognition
>low intrinic activity at DA receptors alleviates psychosis without elevating prolactin or inducing compulsive disorders
>potent 5ht2a and a1b adrenergic antagonism contributes to the antipsychotic effect.

brexpiprazole is the best antipsychotic.