/sci/ - Science & Math

Fluvoxamine, the sigma-1 agonist improves cognition.
>antiparkinson effects of fluvoxamine
https://pubmed.ncbi.nlm.nih.gov/32273939/
https://pubmed.ncbi.nlm.nih.gov/27338206/
>anti Alzheimer's effects of fluvoxamine
https://www.neurologylive.com/view/sigma1-agonists-offer-combination-approach-to-dementia-symptoms
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819237/
>general cognition enhancing effects of fluvoxamine
https://pubmed.ncbi.nlm.nih.gov/20373470/
>sigma-1 agonists raise acetylcholine in the frontal lobes and hippocampus but not the striatum and reverse memory impairment from muscarinic blockade
https://pubmed.ncbi.nlm.nih.gov/20060423/
>fluvoxamine dopamine in the frontal lobes
https://pubmed.ncbi.nlm.nih.gov/21487652/

Brexpiprazole, the a1 blocker, dopamine partial agonist, a2c adrenergic antagonist, 5ht1a agonist, 5ht2a, 5ht7 and mild 5ht6 antagonist improves cognition (better than aripiprazole)
>prazosin (a1 blocker) prevents memory deterioration in Alzheimer's
https://pubmed.ncbi.nlm.nih.gov/23063647/
>a1 blocker reduces risk of parkinson's
https://medicine.uiowa.edu/content/prostate-drug-associated-lower-risk-parkinsons-disease
>5ht1a agonism increases dopamine and acetylcholine in the PFC
https://www.sciencedirect.com/science/article/abs/pii/S0166432808002933?via%3Dihub
>5ht1a agonism raises striatal dopamine
https://pubmed.ncbi.nlm.nih.gov/15906386/
>cognitive benefits of a2c adrenergic antagonism
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558054/
I take max dose of these plus use nicotine and cannabis vape and drink shiraz red wine

300mg luvox
>antiparkinson, antipsychotic, promnesic and frontal cortex enhancing effects via potent sigma-1 activation and SERT inhibition
100mg atomoxetine
>promnesic effects and raises catecholamine 3-fold in the PFC via norepinephrine uptake inhibition
>NMDA antagonist
>non abuseable ADHD drug
4mg brexpiprazole
>antiparkinson effects via a1b blockade
>boosts dopamine and acetylcholine in the PFC via 5ht1a activation and a2c adrenergic inhibition.
>antipsychotic
Nicotine gum
>anti-alzheimer's, promnesic effects
Cannabis
>promotes myelination

>300mg luvox (SSRI and potent sigma-1 agonist) (enhances neurogenesis, neurite-outgrowth and D1R signaling)
>100mg atomoxetine (non-abuseable ADHD drug) (Norepinephrine uptake inhibitor and NMDA antagonist) (increases PFC function)
>4mg brexpiprazole (5ht2a, 5ht7, a1 & a2c adrenergic antagonist. 5ht1a and d2/d3 partial agonist) (enhances effects of psychostimulants, nicotine, opioids and neurogenesis and neurite-outgrowth)
>multivitamins + minerals
>fish oil
>nicotine (tobacco and gum)
>occasional weed and red wine

>280mg ritalin (pro-social, nootropic, euphoriant drug)
>300mg luvox (sigma-1 agonist and serotonin uptake inhibitor)
>4mg brexpiprazole (partial agonist at 5ht1a, d2/d3 and 5ht2c and antagonist at 5ht7 and a2c & a1b adrenergic receptors)
>nicotine gum and alcohol to potentiate ritalin

>>14560476
Define "feminine"