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>> No.10249407 [View]
File: 129 KB, 1389x583, Helix Propensity.png [View same] [iqdb] [saucenao] [google]
10249407

>>10248912
>Helices observed in proteins can range from four to over forty residues long, but a typical helix contains about ten amino acids (about three turns).
This sentence in the Wikipedia article is relevant to creating a program that categorizes amino acid sequences into two categories 1. Alpha helix 2. Beta-pleated sheet. Unfortunately, there's no source for the quoted sentence. Also, I need more specific information that. I can figure out the search space based on the information provided by the quoted sentence (assuming it's accurate), but that's about it.

The paragraph on Amino-acid propensities is relevant, but doesn't get anywhere near the precision I'm looking for. At least there's a source cited. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1299714/
Pic related. The problem with this source though is that it only evaluates individual amino acids, rather than sequences of amino acids. Even then, only approximations are provided. The article is also twenty years old. It's hard to believe there hasn't been more detailed and precise data gathered since then.

>>10248903
>>10249149
What I'd like to do is create a perfect information program. Google Deep Mind and others only approximate.

Everyone tries to jump straight to proteins. It would be more logical to focus on the secondary structure first. Even focusing just on protein domains would be better than the current approach.

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