/sci/ - Science & Math

>>2838400
I don't study that topic much but one of the PIs at my school studies telomere regulation, but I'm not sure how much one would want active telomerase in cells as without some way of preventing DNA damage.

>>2838434
Don't listen to this person he's batshit insane

>>2838405
I don't know about it increasing or decreasing, but I can tell you that with all repair mechanisms and the fidelity of replication machinery there is only a mistake in DNA replication once per 10^9 bases added. But for mutation as say from the Sun or some other chemical mutagen when it comes to alleles it's extremely hard for a new "mutant" allele to gain a foothold in a relatively large population and often go to fixation at 0 relatively quickly.

Ask a genetics graduate student reading papers anything

>>2768394
we want to be able to generate them in the lab. well really first we'd like to be able to generate the progenitor cells cause you can culture and expand those, and hopefully we'll be able to inject them into brains and have them functionally myelinate. Then hopefully we could transfer that tech to iPS cells.

>>2768397
I don't go to Wisc, but I know the lab you are talking about (Zhang). We are one of their main competitors. There are a few labs around the country working on this and we're one of them, but going about it in a few different ways.
I went to Ohio State and my major was Molecular Genetics
I got accepted into an umbrella program and then went to the lab I'm in now

>>2768404
It's not really that fucked. Our lab has both public and private funding. Believe it or not the US spends more money on scientific research than any other country. It would be better though if there wasn't so much religious objection to the use of human ES cells. The court case that's trying to stop funding to human es work is actually being brought by a researcher who works on adult stem cells. I actually really hate her.

>>2768332
nope. That will probably never happen in the US, at least for a very long time. Maybe in some country like

>>2768341
Well it's kind of shitty, but ethics and standard practices were different back then so I don't really fault them too much. But without them lots of advances would never have come to be. And for those that say her family should get some money for the commercialization of the cells that's debatable as they didn't have the expertise or equipment to commercialize them so they would have just died and gone to waste.

>>2768275
They can be made lots of things from all of the germ layers. I work on glial tissues. Something that's really cool is recently they differentiated beating cardiomyocytes from ES cells

>>2768279
My degree is in Molecular Genetics

>>2768283
>What's your field of research here?
I work on directed differentiation of Human ES cells to glial cell types, specifically oligodendrocytes.
>Henriette Lacks
what about her specifically? that she was the source of HeLa cells? Idk what you're really asking or want to know.

>>2768259
It's fun and there's an overpopulation problem. but really I've never murdered any babies. The stem cells I use were derived long ago probably back when I was still in high school.

Ok I'm going to be up until the end of the Wisconsin game

So until then.


Ask someone who does research on/with stem cells anything.