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/jp/ - Otaku Culture

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8076529 No.8076529 [Reply] [Original]

Today's lucky item . . . frayed telomeres.

>> No.8076539

Don't pick on DNA ligase-tan! It's not her fault that she's a clumsy girl who cannot ligate the Okazaki fragments on telomeres and inadvertently causes their shortening.

>> No.8076540
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8076540

Thank you for your fortune-telling skills. Good night /jp/

>> No.8076548

>>8076540

We are, as always, your humble servant.

>> No.8076552

What happens if I have the lucky item?

>> No.8076562

>>8076552

Then you have to appear in Gundam Seed Destiny.

>> No.8076574
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8076574

>>8076562

>> No.8076577
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8076577

>>8076574

I can't deal with this.

>> No.8076593

>>8076539
Ever hear of telomerase? It kinda solves that problem flawlessly. The only reason tolemeres shorten is because they're programmed to so cells don't become cancerous. Telomere shortening itself has little if anything to do with aging, it just helps carry out cell death that is still required for a so-called immortal body. Aging is mostly due to the accumulation of waste that the body has no way of disposing and general damage from wear and tear.

They actually ran an experiment in which the lifespan of mice was increased by 10x by inactivating a gene that causes aging. Would be nice to see it used in humans soon.

>> No.8076624

>>8076593
I know about telomerase, but then it's only expressed when you're going to do a lot of dividing, as is the case for say, stem cells. Somatic cells don't normally express telomerase, it's often a sign of cancer when they start doing that. Also, if we're talking about the same experiment, that was on mice that had aging defects to begin with.

>Aging is mostly due to the accumulation of waste that the body has no way of disposing and general damage from wear and tear.

Nah, aging is fairly controlled. This is because it's not really useful from an evolutionary standpoint to live beyond reproductive age, so it's smooth sailing for stuff that tends to kill you after you're done and over with reproduction. Those accumulate over time and now no one gets to live long. Fucking evolution.

>>
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