/ck/ - Food & Cooking

>>18008388
>>18008248
>>18008389
I've already posted the studies regarding BCAA and insulin resistance. Let me post the highlights since you apparently can't read:
>BCAA catabolism is lost during the development and progression of multiple cancers
>BCAA catabolic enzyme expression predicts tumor aggressiveness and patient survival
>Tumors display increased BCAA content and enhanced mTORC1 activation
>Dietary BCAAs correlate with tumor burden in mice and cancer mortality in humans
>brain insulin controls BCAA metabolism in humans. Thus, brain insulin resistance could account at least in part for the elevated BCAA levels observed in the insulin-resistant state.
>increased circulating levels of BCAAs increase insulin-resistant obesity and T2DM, as well as the observations that these increases might predict future insulin resistance or T2DM
>a reduced BCAA diet promotes rapid fat mass loss without calorie restriction in obese mice.
>Selective reduction of dietary BCAAs also restores glucose tolerance and insulin sensitivity to obese mice, even as they continue to consume a high‐fat, high‐sugar diet.
>A low BCAA diet transiently induces FGF21 (fibroblast growth factor 21) and increases energy expenditure.
>dietary protein quality (i.e. the precise macronutrient composition of dietary protein) impact the effectiveness of weight-loss diets.
>a diet with reduced levels of branched-chain amino acids (BCAAs), which are associated with insulin resistance in both humans and rodents, modestly improves glucose tolerance and slows fat mass gain.
Now fuck off. All of this is mechanistic and has been proven over and over again. If you want to get Alzheimer's, then that's your choice. Just please keep your fucking mouth shut about things you know NOTHING about.

Earl Grey, obviously