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>>49615265
>A UK health worker caring for a monkey patient developed a skin rash 18 days later in the first case of hospital transmission of the infection outside of Africa.
Contrary to the classic description of monkey, the rash appeared without the health worker having had a fever, headache, or muscle aches in the preceding days. She also did not have swollen glands at any time, which is considered another classic symptom of the disease. She had 32 pustules on her face, trunk, hands and labia majora of the vulva. The one that made her suffer the most was one that grew under her thumbnail and broke the nail.
The health worker had received the Imvanex smallpox vaccine six days after caring for the monkey patient, who had just returned from Nigeria, but the vaccine did not protect her. She received the antiviral drug brincidofovir, but it was toxic to her liver and the doctors decided to stop the treatment. What is most surprising about her case is that although the rash lasted for two weeks, she still had detectable virus DNA in her blood 30 days after the onset of symptoms and in her upper respiratory tract up to day 41.
“In previous cases and outbreaks of monkey patients have been considered infectious until all skin lesions have crusted over,” write researchers from the UK National Health Service (NHS) in The Lancet Infectious journal. Diseases, where they present the case today. The finding that some patients continue to have detectable virus DNA when skin wounds have healed suggests that they may be contagious after symptoms end.