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>> No.1975071 [View]
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1975071

>data comes out
>it's good
>dips anyway
WEW
They just proved that their non-stimulant ADHD medication works in patients who have the gene mutation they were targeting. That's a big fucking deal. It might treat autism too.

>The recent analysis demonstrates that of the 42 patients with a mutation in one of nine genes (n=18 patients on treatment, n=24 patients on placebo), 89% of patients on treatment (n=16) had a clinically meaningful and statistically significant response to AEVI-001 in the SAGA trial (defined as a 30% or greater reduction in ADHD-RS score from baseline), vs 21% on placebo (p < .0001). Patients on treatment had a reduction in ADHD-RS of 17.6 versus 5.9 on placebo (p < .005). This subset of patients had mutations in the CNTN4 gene as well as certain GRM and neurodevelopmental genes.
Why is it down

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